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Q96LB8

- PGRP4_HUMAN

UniProt

Q96LB8 - PGRP4_HUMAN

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Protein

Peptidoglycan recognition protein 4

Gene

PGLYRP4

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.1 Publication

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei263 – 2631Murein
Binding sitei274 – 2741Murein

GO - Molecular functioni

  1. N-acetylmuramoyl-L-alanine amidase activity Source: InterPro
  2. peptidoglycan binding Source: UniProtKB
  3. peptidoglycan receptor activity Source: UniProtKB
  4. zinc ion binding Source: InterPro

GO - Biological processi

  1. defense response to Gram-positive bacterium Source: UniProtKB
  2. detection of bacterium Source: UniProtKB
  3. growth of symbiont in host Source: Ensembl
  4. innate immune response Source: UniProtKB
  5. negative regulation of interferon-gamma production Source: Ensembl
  6. negative regulation of natural killer cell differentiation involved in immune response Source: Ensembl
  7. pattern recognition receptor signaling pathway Source: GOC
  8. peptidoglycan catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Antibiotic, Antimicrobial

Keywords - Biological processi

Immunity, Innate immunity

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidoglycan recognition protein 4
Alternative name(s):
Peptidoglycan recognition protein I-beta
Short name:
PGLYRPIbeta
Short name:
PGRP-I-beta
Peptidoglycan recognition protein intermediate beta
Gene namesi
Name:PGLYRP4
Synonyms:PGRPIB
ORF Names:SBBI67
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 1

Organism-specific databases

HGNCiHGNC:30015. PGLYRP4.

Subcellular locationi

Secreted 1 Publication

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-KW
  2. intracellular Source: UniProtKB
  3. membrane Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134902492.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717Sequence AnalysisAdd
BLAST
Chaini18 – 373356Peptidoglycan recognition protein 4PRO_0000023924Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi22 – 221N-linked (GlcNAc...)Sequence Analysis
Glycosylationi39 – 391N-linked (GlcNAc...)Sequence Analysis
Glycosylationi109 – 1091N-linked (GlcNAc...)Sequence Analysis
Glycosylationi145 – 1451N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi210 ↔ 3321 Publication
Disulfide bondi226 ↔ 2701 Publication
Disulfide bondi246 ↔ 2521 Publication
Glycosylationi247 – 2471N-linked (GlcNAc...)Sequence Analysis

Post-translational modificationi

N-glycosylated.1 Publication

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ96LB8.
PRIDEiQ96LB8.

PTM databases

PhosphoSiteiQ96LB8.

Expressioni

Tissue specificityi

Detected in skin epidermis, eccrine sweat glands and ducts, mucous cells in the submandibular salivary gland, mucous cells in the throat, ciliary body epithelial cells of the eye, small intestine, colon, stomach and in mature epithelial cells of the tongue (at protein level). High expression in skin and esophagus. Expressed also to a much lesser extent in the tonsils and thymus.2 Publications

Inductioni

Up-regulated by exposure to Gram-positive and Gram-negative bacteria.1 Publication

Gene expression databases

BgeeiQ96LB8.
CleanExiHS_PGLYRP4.
GenevestigatoriQ96LB8.

Organism-specific databases

HPAiCAB025879.

Interactioni

Subunit structurei

Homodimer; disulfide-linked. Heterodimer with PGLYRP3; disulfide-linked.2 Publications

Protein-protein interaction databases

STRINGi9606.ENSP00000352672.

Structurei

Secondary structure

1
373
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi216 – 2194Combined sources
Beta strandi231 – 24010Combined sources
Helixi249 – 26517Combined sources
Beta strandi275 – 2784Combined sources
Beta strandi284 – 2885Combined sources
Beta strandi290 – 2923Combined sources
Turni298 – 3003Combined sources
Helixi301 – 3033Combined sources
Beta strandi304 – 3118Combined sources
Beta strandi314 – 3163Combined sources
Helixi320 – 33516Combined sources
Beta strandi338 – 34710Combined sources
Helixi348 – 3514Combined sources
Beta strandi352 – 3543Combined sources
Helixi359 – 3657Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2EAVX-ray2.20A/B214-373[»]
2EAXX-ray2.10A/B/C214-373[»]
ProteinModelPortaliQ96LB8.
SMRiQ96LB8. Positions 56-187, 210-373.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ96LB8.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni293 – 30210Interaction with murein
Regioni353 – 3542Interaction with murein

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG241935.
GeneTreeiENSGT00390000016833.
HOVERGENiHBG053579.
InParanoidiQ96LB8.
KOiK01446.
OMAiHTAGRTC.
OrthoDBiEOG757CZ5.
PhylomeDBiQ96LB8.
TreeFamiTF323898.

Family and domain databases

Gene3Di3.40.80.10. 2 hits.
InterProiIPR002502. Amidase_domain.
IPR015510. PGRP.
IPR006619. PGRP_domain_met/bac.
[Graphical view]
PANTHERiPTHR11022. PTHR11022. 1 hit.
PfamiPF01510. Amidase_2. 2 hits.
[Graphical view]
SMARTiSM00644. Ami_2. 2 hits.
SM00701. PGRP. 2 hits.
[Graphical view]
SUPFAMiSSF55846. SSF55846. 2 hits.

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q96LB8-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MLPWLLVFSA LGIQAWGDSS WNKTQAKQVS EGLQYLFENI SQLTEKGLPT
60 70 80 90 100
DVSTTVSRKA WGAEAVGCSI QLTTPVNVLV IHHVPGLECH DQTVCSQRLR
110 120 130 140 150
ELQAHHVHNN SGCDVAYNFL VGDDGRVYEG VGWNIQGVHT QGYNNISLGF
160 170 180 190 200
AFFGTKKGHS PSPAALSAME NLITYAVQKG HLSSSYVQPL LGKGENCLAP
210 220 230 240 250
RQKTSLKKAC PGVVPRSVWG ARETHCPRMT LPAKYGIIIH TAGRTCNISD
260 270 280 290 300
ECRLLVRDIQ SFYIDRLKSC DIGYNFLVGQ DGAIYEGVGW NVQGSSTPGY
310 320 330 340 350
DDIALGITFM GTFTGIPPNA AALEAAQDLI QCAMVKGYLT PNYLLVGHSD
360 370
VARTLSPGQA LYNIISTWPH FKH
Length:373
Mass (Da):40,620
Last modified:April 3, 2007 - v2
Checksum:i8E882E1FF608F6F3
GO
Isoform 2 (identifier: Q96LB8-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     47-50: Missing.

Show »
Length:369
Mass (Da):40,252
Checksum:i1D03920B70BDE735
GO

Sequence cautioni

The sequence AAF99599.1 differs from that shown. Reason: Frameshift at positions 209, 224 and 227. Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti3 – 31P → L.2 Publications
Corresponds to variant rs12096209 [ dbSNP | Ensembl ].
VAR_050503
Natural varianti13 – 131I → L.3 Publications
Corresponds to variant rs3006458 [ dbSNP | Ensembl ].
VAR_033283
Natural varianti92 – 921Q → R.
Corresponds to variant rs3006453 [ dbSNP | Ensembl ].
VAR_031586
Natural varianti192 – 1921G → V.3 Publications
Corresponds to variant rs3006448 [ dbSNP | Ensembl ].
VAR_031587
Natural varianti213 – 2131V → I.2 Publications
Corresponds to variant rs12063091 [ dbSNP | Ensembl ].
VAR_031588
Natural varianti301 – 3011D → N.
Corresponds to variant rs35347202 [ dbSNP | Ensembl ].
VAR_031589

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei47 – 504Missing in isoform 2. 1 PublicationVSP_024388

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY035377 mRNA. Translation: AAK72485.1.
AF242518 mRNA. Translation: AAF99599.1. Frameshift.
AK292203 mRNA. Translation: BAF84892.1.
AL591704 Genomic DNA. Translation: CAI19492.1.
AL591704 Genomic DNA. Translation: CAI19493.1.
BC142636 mRNA. Translation: AAI42637.1.
BC107157 mRNA. Translation: AAI07158.1.
BC107158 mRNA. Translation: AAI07159.1.
CCDSiCCDS30871.1. [Q96LB8-1]
RefSeqiNP_065126.2. NM_020393.2. [Q96LB8-1]
UniGeneiHs.58356.

Genome annotation databases

EnsembliENST00000359650; ENSP00000352672; ENSG00000163218. [Q96LB8-1]
ENST00000368739; ENSP00000357728; ENSG00000163218. [Q96LB8-2]
GeneIDi57115.
KEGGihsa:57115.
UCSCiuc001fbo.3. human. [Q96LB8-1]
uc001fbp.3. human. [Q96LB8-2]

Polymorphism databases

DMDMi143811439.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY035377 mRNA. Translation: AAK72485.1 .
AF242518 mRNA. Translation: AAF99599.1 . Frameshift.
AK292203 mRNA. Translation: BAF84892.1 .
AL591704 Genomic DNA. Translation: CAI19492.1 .
AL591704 Genomic DNA. Translation: CAI19493.1 .
BC142636 mRNA. Translation: AAI42637.1 .
BC107157 mRNA. Translation: AAI07158.1 .
BC107158 mRNA. Translation: AAI07159.1 .
CCDSi CCDS30871.1. [Q96LB8-1 ]
RefSeqi NP_065126.2. NM_020393.2. [Q96LB8-1 ]
UniGenei Hs.58356.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2EAV X-ray 2.20 A/B 214-373 [» ]
2EAX X-ray 2.10 A/B/C 214-373 [» ]
ProteinModelPortali Q96LB8.
SMRi Q96LB8. Positions 56-187, 210-373.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9606.ENSP00000352672.

PTM databases

PhosphoSitei Q96LB8.

Polymorphism databases

DMDMi 143811439.

Proteomic databases

PaxDbi Q96LB8.
PRIDEi Q96LB8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000359650 ; ENSP00000352672 ; ENSG00000163218 . [Q96LB8-1 ]
ENST00000368739 ; ENSP00000357728 ; ENSG00000163218 . [Q96LB8-2 ]
GeneIDi 57115.
KEGGi hsa:57115.
UCSCi uc001fbo.3. human. [Q96LB8-1 ]
uc001fbp.3. human. [Q96LB8-2 ]

Organism-specific databases

CTDi 57115.
GeneCardsi GC01M153302.
H-InvDB HIX0028539.
HGNCi HGNC:30015. PGLYRP4.
HPAi CAB025879.
MIMi 608198. gene.
neXtProti NX_Q96LB8.
PharmGKBi PA134902492.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG241935.
GeneTreei ENSGT00390000016833.
HOVERGENi HBG053579.
InParanoidi Q96LB8.
KOi K01446.
OMAi HTAGRTC.
OrthoDBi EOG757CZ5.
PhylomeDBi Q96LB8.
TreeFami TF323898.

Miscellaneous databases

EvolutionaryTracei Q96LB8.
GenomeRNAii 57115.
NextBioi 62975.
PROi Q96LB8.
SOURCEi Search...

Gene expression databases

Bgeei Q96LB8.
CleanExi HS_PGLYRP4.
Genevestigatori Q96LB8.

Family and domain databases

Gene3Di 3.40.80.10. 2 hits.
InterProi IPR002502. Amidase_domain.
IPR015510. PGRP.
IPR006619. PGRP_domain_met/bac.
[Graphical view ]
PANTHERi PTHR11022. PTHR11022. 1 hit.
Pfami PF01510. Amidase_2. 2 hits.
[Graphical view ]
SMARTi SM00644. Ami_2. 2 hits.
SM00701. PGRP. 2 hits.
[Graphical view ]
SUPFAMi SSF55846. SSF55846. 2 hits.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Peptidoglycan recognition proteins: a novel family of four human innate immunity pattern recognition molecules."
    Liu C., Xu Z., Gupta D., Dziarski R.
    J. Biol. Chem. 276:34686-34694(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY, VARIANTS LEU-13 AND VAL-192.
  2. Zhang W., Wan T., Cao X.
    Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), VARIANTS LEU-3 AND ILE-213.
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS LEU-13 AND VAL-192.
    Tissue: Esophagus.
  4. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANTS LEU-3; LEU-13; VAL-192 AND ILE-213.
  6. "Peptidoglycan recognition proteins are a new class of human bactericidal proteins."
    Lu X., Wang M., Qi J., Wang H., Li X., Gupta D., Dziarski R.
    J. Biol. Chem. 281:5895-5907(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBUNIT, GLYCOSYLATION, INDUCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
  7. "Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins."
    Cho S., Wang Q., Swaminathan C.P., Hesek D., Lee M., Boons G.-J., Mobashery S., Mariuzza R.A.
    Proc. Natl. Acad. Sci. U.S.A. 104:8761-8766(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 210-373 IN COMPLEX WITH PEPTIDOGLYCAN-PEPTIDE, SUBUNIT, DISULFIDE BONDS.

Entry informationi

Entry nameiPGRP4_HUMAN
AccessioniPrimary (citable) accession number: Q96LB8
Secondary accession number(s): A8K838
, Q3B822, Q3B823, Q5SY63, Q5SY64, Q9HD75
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: April 3, 2007
Last modified: November 26, 2014
This is version 112 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3