Unreviewed, UniProtKB/TrEMBL Q96LA2 (Q96LA2_HUMAN)

Names and origin

Protein names	Submitted name:     Interferon gamma EMBL AAK95388.1
Organism	Homo sapiens (Human) EMBL AAK95388.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	143 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Biological process	antigen processing and presentation Inferred from electronic annotation. Source: Compara defense response to bacterium Inferred from electronic annotation. Source: Compara endoplasmic reticulum unfolded protein response Inferred from electronic annotation. Source: Compara immune response Inferred from electronic annotation. Source: InterPro inflammatory cell apoptosis Inferred from electronic annotation. Source: Compara negative regulation of cell proliferation Inferred from electronic annotation. Source: Compara negative regulation of myelination Inferred from electronic annotation. Source: Compara neutrophil apoptosis Inferred from electronic annotation. Source: Compara neutrophil chemotaxis Inferred from electronic annotation. Source: Compara positive regulation of MHC class II biosynthetic process Inferred from electronic annotation. Source: Compara positive regulation of T cell proliferation Inferred from electronic annotation. Source: Compara positive regulation of chemokine biosynthetic process Inferred from electronic annotation. Source: Compara positive regulation of interleukin-1 beta secretion Inferred from electronic annotation. Source: Compara positive regulation of interleukin-12 biosynthetic process Inferred from electronic annotation. Source: Compara positive regulation of interleukin-6 biosynthetic process Inferred from electronic annotation. Source: Compara positive regulation of isotype switching to IgG isotypes Inferred from electronic annotation. Source: Compara positive regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: Compara
Cellular component	extracellular space Inferred from electronic annotation. Source: Compara
Molecular function	cytokine activity Inferred from electronic annotation. Source: Compara interferon-gamma receptor binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAK95388.1

Sequences

	Sequence		Length	Mass (Da)
	Q96LA2-1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 5BC92B1B8B0E03DD	FASTA	143	16,787
	10 20 30 40 50 60 QDPYVKEAEN LKKYFNAGHS DVADNGTLFL GILKNWKEES DRKIMQSQIV SFYFKLFKNF 70 80 90 100 110 120 KDDQSIQKSV ETIKEDMNVK FFNSNKKKRD DFEKLTNYSV TDLNVQRKAI HELIQVMAEL 130 140 PPAAETGKRK RSQMLFRGRR ASQ

References

[1]	"Variant of Human Interferon Gamma." Mukherjee K.J., Pandey G., Bhattacharya P.III. Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY044154 mRNA. Translation: AAK95388.1.
IPI	IPI00307209.
UniGene	Hs.856
3D structure databases
HSSP	HSSP built from PDB template 1FYH based on UniProtKB P01579.
SMR	Q96LA2. Positions 1-132.
ModBase	Search...
Protein-protein interaction databases
STRING	Q96LA2.
Genome annotation databases
Ensembl	ENST00000229135; ENSP00000229135; ENSG00000111537; Homo sapiens. [Genome view]
Organism-specific databases
HGNC	HGNC:5438. IFNG.
Phylogenomic databases
HOVERGEN	Q96LA2.
Gene expression databases
ArrayExpress	Q96LA2.
Bgee	Q96LA2.
Family and domain databases
InterPro	IPR009079. 4_helix_cytokine-like_core. IPR002069. Interferon_gamma. [Graphical view]
PANTHER	PTHR11419. IFN-gamma. 1 hit.
Pfam	PF00714. IFN-gamma. 1 hit. [Graphical view]
PIRSF	PIRSF001936. IFN-gamma. 1 hit.
ProDom	PD002435. Interferon_gamma. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

Q96LA2_HUMAN

Accession

Primary (citable) accession number: Q96LA2

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	January 19, 2010
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.