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Unreviewed, UniProtKB/TrEMBL Q96LA2 (Q96LA2_HUMAN)

Last modified January 19, 2010. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

Names and origin

Protein namesSubmitted name:
    Interferon gamma EMBL AAK95388.1
OrganismHomo sapiens (Human) EMBL AAK95388.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length143 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level.

Ontologies

Gene Ontology (GO)
   Biological processantigen processing and presentation

Inferred from electronic annotation. Source: Compara

defense response to bacterium

Inferred from electronic annotation. Source: Compara

endoplasmic reticulum unfolded protein response

Inferred from electronic annotation. Source: Compara

immune response

Inferred from electronic annotation. Source: InterPro

inflammatory cell apoptosis

Inferred from electronic annotation. Source: Compara

negative regulation of cell proliferation

Inferred from electronic annotation. Source: Compara

negative regulation of myelination

Inferred from electronic annotation. Source: Compara

neutrophil apoptosis

Inferred from electronic annotation. Source: Compara

neutrophil chemotaxis

Inferred from electronic annotation. Source: Compara

positive regulation of MHC class II biosynthetic process

Inferred from electronic annotation. Source: Compara

positive regulation of T cell proliferation

Inferred from electronic annotation. Source: Compara

positive regulation of chemokine biosynthetic process

Inferred from electronic annotation. Source: Compara

positive regulation of interleukin-1 beta secretion

Inferred from electronic annotation. Source: Compara

positive regulation of interleukin-12 biosynthetic process

Inferred from electronic annotation. Source: Compara

positive regulation of interleukin-6 biosynthetic process

Inferred from electronic annotation. Source: Compara

positive regulation of isotype switching to IgG isotypes

Inferred from electronic annotation. Source: Compara

positive regulation of transcription, DNA-dependent

Inferred from electronic annotation. Source: Compara

   Cellular componentextracellular space

Inferred from electronic annotation. Source: Compara

   Molecular functioncytokine activity

Inferred from electronic annotation. Source: Compara

interferon-gamma receptor binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAK95388.1

Sequences

Sequence LengthMass (Da)Tools
Q96LA2-1 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 5BC92B1B8B0E03DD

FASTA14316,787
        10         20         30         40         50         60 
QDPYVKEAEN LKKYFNAGHS DVADNGTLFL GILKNWKEES DRKIMQSQIV SFYFKLFKNF 

        70         80         90        100        110        120 
KDDQSIQKSV ETIKEDMNVK FFNSNKKKRD DFEKLTNYSV TDLNVQRKAI HELIQVMAEL 

       130        140 
PPAAETGKRK RSQMLFRGRR ASQ 

« Hide

References

[1]"Variant of Human Interferon Gamma."
Mukherjee K.J., Pandey G., Bhattacharya P.III.
Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY044154 mRNA. Translation: AAK95388.1.
IPIIPI00307209.
UniGeneHs.856

3D structure databases

HSSPHSSP built from PDB template 1FYH based on UniProtKB P01579.
SMRQ96LA2. Positions 1-132.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ96LA2.

Genome annotation databases

EnsemblENST00000229135; ENSP00000229135; ENSG00000111537; Homo sapiens. [Genome view]

Organism-specific databases

HGNCHGNC:5438. IFNG.

Phylogenomic databases

HOVERGENQ96LA2.

Gene expression databases

ArrayExpressQ96LA2.
BgeeQ96LA2.

Family and domain databases

InterProIPR009079. 4_helix_cytokine-like_core.
IPR002069. Interferon_gamma.
[Graphical view]
PANTHERPTHR11419. IFN-gamma. 1 hit.
PfamPF00714. IFN-gamma. 1 hit.
[Graphical view]
PIRSFPIRSF001936. IFN-gamma. 1 hit.
ProDomPD002435. Interferon_gamma. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Entry information

Entry nameQ96LA2_HUMAN
AccessionPrimary (citable) accession number: Q96LA2
Entry history
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: January 19, 2010
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information