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Q96L34

- MARK4_HUMAN

UniProt

Q96L34 - MARK4_HUMAN

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Protein
MAP/microtubule affinity-regulating kinase 4
Gene
MARK4, KIAA1860, MARKL1
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Enzyme regulationi

Activated by phosphorylation on Thr-214.1 Publication

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei88 – 881ATP By similarity
Active sitei181 – 1811Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi65 – 739ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB
  2. gamma-tubulin binding Source: UniProtKB
  3. microtubule binding Source: UniProtKB
  4. protein binding Source: IntAct
  5. protein serine/threonine kinase activity Source: UniProtKB
  6. tau-protein kinase activity Source: UniProtKB
  7. ubiquitin binding Source: UniProtKB

GO - Biological processi

  1. microtubule bundle formation Source: UniProtKB
  2. microtubule cytoskeleton organization Source: UniProtKB
  3. nervous system development Source: UniProtKB
  4. positive regulation of programmed cell death Source: UniProtKB
  5. protein phosphorylation Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiQ96L34.

Names & Taxonomyi

Protein namesi
Recommended name:
MAP/microtubule affinity-regulating kinase 4 (EC:2.7.11.1)
Alternative name(s):
MAP/microtubule affinity-regulating kinase-like 1
Gene namesi
Name:MARK4
Synonyms:KIAA1860, MARKL1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 19

Organism-specific databases

HGNCiHGNC:13538. MARK4.

Subcellular locationi

GO - Cellular componenti

  1. centrosome Source: UniProtKB
  2. microtubule cytoskeleton Source: UniProtKB
  3. microtubule organizing center Source: UniProtKB
  4. neuron projection Source: UniProtKB
Complete GO annotation...

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi214 – 2141T → A: Prevents phosphorylation and activation by STK11/LKB1 complex. 1 Publication
Mutagenesisi214 – 2141T → E: Mimicks phosphorylation state, leading to increased activity. 1 Publication

Organism-specific databases

PharmGKBiPA30641.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 752752MAP/microtubule affinity-regulating kinase 4
PRO_0000086307Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei214 – 2141Phosphothreonine; by LKB11 Publication

Post-translational modificationi

Ubiquitinated with 'Lys-29'- and 'Lys-33'-linked polyubiquitins which appear to impede LKB1-mediated phosphorylation. Deubiquitinated by USP9X.1 Publication
Phosphorylated at Thr-214 by STK11/LKB1 in complex with STE20-related adapter-alpha (STRADA) pseudo kinase and CAB39.1 Publication

Keywords - PTMi

Phosphoprotein, Ubl conjugation

Proteomic databases

MaxQBiQ96L34.
PaxDbiQ96L34.
PRIDEiQ96L34.

PTM databases

PhosphoSiteiQ96L34.

Expressioni

Tissue specificityi

Ubiquitous. Isoform 2 is brain-specific.1 Publication

Gene expression databases

ArrayExpressiQ96L34.
BgeeiQ96L34.
CleanExiHS_MARK4.
GenevestigatoriQ96L34.

Organism-specific databases

HPAiHPA039186.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CDC42P609532EBI-302319,EBI-81752
PARD6GQ9BYG42EBI-302319,EBI-295417
PNMA1Q8ND902EBI-302319,EBI-302345
PRKCIP417432EBI-302319,EBI-286199
STK11Q158312EBI-302319,EBI-306838
TUBG1P232584EBI-302319,EBI-302589
YWHAHQ049176EBI-302319,EBI-306940

Protein-protein interaction databases

BioGridi121760. 40 interactions.
IntActiQ96L34. 28 interactions.
MINTiMINT-6425023.
STRINGi9606.ENSP00000300843.

Structurei

3D structure databases

ProteinModelPortaliQ96L34.
SMRiQ96L34. Positions 53-369, 653-752.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini59 – 310252Protein kinase
Add
BLAST
Domaini324 – 36845UBA
Add
BLAST
Domaini703 – 75250KA1
Add
BLAST

Sequence similaritiesi

Contains 1 UBA domain.

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000233025.
HOVERGENiHBG052453.
InParanoidiQ96L34.
KOiK08798.
OMAiDSMSTPN.
OrthoDBiEOG79CXXX.
PhylomeDBiQ96L34.
TreeFamiTF315213.

Family and domain databases

Gene3Di3.30.310.80. 1 hit.
InterProiIPR028375. KA1/Ssp2_C.
IPR001772. KA1_dom.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR015940. UBA/transl_elong_EF1B_N_euk.
IPR000449. UBA/Ts_N.
[Graphical view]
PfamiPF02149. KA1. 1 hit.
PF00069. Pkinase. 1 hit.
PF00627. UBA. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
SM00165. UBA. 1 hit.
[Graphical view]
SUPFAMiSSF103243. SSF103243. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50032. KA1. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
PS50030. UBA. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q96L34-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MSSRTVLAPG NDRNSDTHGT LGSGRSSDKG PSWSSRSLGA RCRNSIASCP    50
EEQPHVGNYR LLRTIGKGNF AKVKLARHIL TGREVAIKII DKTQLNPSSL 100
QKLFREVRIM KGLNHPNIVK LFEVIETEKT LYLVMEYASA GEVFDYLVSH 150
GRMKEKEARA KFRQIVSAVH YCHQKNIVHR DLKAENLLLD AEANIKIADF 200
GFSNEFTLGS KLDTFCGSPP YAAPELFQGK KYDGPEVDIW SLGVILYTLV 250
SGSLPFDGHN LKELRERVLR GKYRVPFYMS TDCESILRRF LVLNPAKRCT 300
LEQIMKDKWI NIGYEGEELK PYTEPEEDFG DTKRIEVMVG MGYTREEIKE 350
SLTSQKYNEV TATYLLLGRK TEEGGDRGAP GLALARVRAP SDTTNGTSSS 400
KGTSHSKGQR SSSSTYHRQR RHSDFCGPSP APLHPKRSPT STGEAELKEE 450
RLPGRKASCS TAGSGSRGLP PSSPMVSSAH NPNKAEIPER RKDSTSTPNN 500
LPPSMMTRRN TYVCTERPGA ERPSLLPNGK ENSSGTPRVP PASPSSHSLA 550
PPSGERSRLA RGSTIRSTFH GGQVRDRRAG GGGGGGVQNG PPASPTLAHE 600
AAPLPAGRPR PTTNLFTKLT SKLTRRVADE PERIGGPEVT SCHLPWDQTE 650
TAPRLLRFPW SVKLTSSRPP EALMAALRQA TAAARCRCRQ PQPFLLACLH 700
GGAGGPEPLS HFEVEVCQLP RPGLRGVLFR RVAGTALAFR TLVTRISNDL 750
EL 752
Length:752
Mass (Da):82,520
Last modified:December 1, 2001 - v1
Checksum:i4B430FFD2B150E7A
GO
Isoform 2 (identifier: Q96L34-2) [UniParc]FASTAAdd to Basket

Also known as: MARKL1S

The sequence of this isoform differs from the canonical sequence as follows:
     628-752: ADEPERIGGP...VTRISNDLEL → TLDPSKRQNS...PPGCSDSPGV

Show »
Length:688
Mass (Da):75,321
Checksum:iA49143B34FDDD086
GO

Sequence cautioni

The sequence BAB47489.1 differs from that shown. Reason: Erroneous initiation.
The sequence BAB55238.1 differs from that shown. Reason: Erroneous initiation.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti377 – 3771R → Q.1 Publication
Corresponds to variant rs35070611 [ dbSNP | Ensembl ].
VAR_040766
Natural varianti418 – 4181R → C in a colorectal adenocarcinoma sample; somatic mutation. 1 Publication
VAR_040767

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei628 – 752125ADEPE…NDLEL → TLDPSKRQNSNRCVSGASLP QGSKIRSQTNLRESGDLRSQ VAIYLGIKRKPPPGCSDSPG V in isoform 2.
VSP_004946Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti70 – 701F → S in BAB39380. 1 Publication
Sequence conflicti70 – 701F → S in BAC03375. 1 Publication
Sequence conflicti518 – 5181P → L in BAB55238. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY057448 mRNA. Translation: AAL23683.1.
AB049127 mRNA. Translation: BAB39380.1.
AB088047 mRNA. Translation: BAC03375.1.
AY120867 mRNA. Translation: AAM55491.1.
AB058763 mRNA. Translation: BAB47489.1. Different initiation.
AK027619 mRNA. Translation: BAB55238.1. Different initiation.
AK075272 mRNA. Translation: BAC11510.1.
CCDSiCCDS12658.1. [Q96L34-2]
CCDS56097.1. [Q96L34-1]
RefSeqiNP_001186796.1. NM_001199867.1. [Q96L34-1]
NP_113605.2. NM_031417.3. [Q96L34-2]
UniGeneiHs.34314.

Genome annotation databases

EnsembliENST00000262891; ENSP00000262891; ENSG00000007047. [Q96L34-1]
ENST00000300843; ENSP00000300843; ENSG00000007047. [Q96L34-2]
GeneIDi57787.
KEGGihsa:57787.
UCSCiuc002pba.2. human. [Q96L34-2]
uc002pbb.2. human. [Q96L34-1]

Polymorphism databases

DMDMi29840797.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY057448 mRNA. Translation: AAL23683.1 .
AB049127 mRNA. Translation: BAB39380.1 .
AB088047 mRNA. Translation: BAC03375.1 .
AY120867 mRNA. Translation: AAM55491.1 .
AB058763 mRNA. Translation: BAB47489.1 . Different initiation.
AK027619 mRNA. Translation: BAB55238.1 . Different initiation.
AK075272 mRNA. Translation: BAC11510.1 .
CCDSi CCDS12658.1. [Q96L34-2 ]
CCDS56097.1. [Q96L34-1 ]
RefSeqi NP_001186796.1. NM_001199867.1. [Q96L34-1 ]
NP_113605.2. NM_031417.3. [Q96L34-2 ]
UniGenei Hs.34314.

3D structure databases

ProteinModelPortali Q96L34.
SMRi Q96L34. Positions 53-369, 653-752.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 121760. 40 interactions.
IntActi Q96L34. 28 interactions.
MINTi MINT-6425023.
STRINGi 9606.ENSP00000300843.

Chemistry

BindingDBi Q96L34.
ChEMBLi CHEMBL5754.
GuidetoPHARMACOLOGYi 2100.

PTM databases

PhosphoSitei Q96L34.

Polymorphism databases

DMDMi 29840797.

Proteomic databases

MaxQBi Q96L34.
PaxDbi Q96L34.
PRIDEi Q96L34.

Protocols and materials databases

DNASUi 57787.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000262891 ; ENSP00000262891 ; ENSG00000007047 . [Q96L34-1 ]
ENST00000300843 ; ENSP00000300843 ; ENSG00000007047 . [Q96L34-2 ]
GeneIDi 57787.
KEGGi hsa:57787.
UCSCi uc002pba.2. human. [Q96L34-2 ]
uc002pbb.2. human. [Q96L34-1 ]

Organism-specific databases

CTDi 57787.
GeneCardsi GC19P045583.
HGNCi HGNC:13538. MARK4.
HPAi HPA039186.
MIMi 606495. gene.
neXtProti NX_Q96L34.
PharmGKBi PA30641.
HUGEi Search...
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000233025.
HOVERGENi HBG052453.
InParanoidi Q96L34.
KOi K08798.
OMAi DSMSTPN.
OrthoDBi EOG79CXXX.
PhylomeDBi Q96L34.
TreeFami TF315213.

Enzyme and pathway databases

SignaLinki Q96L34.

Miscellaneous databases

GeneWikii MARK4.
GenomeRNAii 57787.
NextBioi 64721.
PROi Q96L34.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q96L34.
Bgeei Q96L34.
CleanExi HS_MARK4.
Genevestigatori Q96L34.

Family and domain databases

Gene3Di 3.30.310.80. 1 hit.
InterProi IPR028375. KA1/Ssp2_C.
IPR001772. KA1_dom.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR015940. UBA/transl_elong_EF1B_N_euk.
IPR000449. UBA/Ts_N.
[Graphical view ]
Pfami PF02149. KA1. 1 hit.
PF00069. Pkinase. 1 hit.
PF00627. UBA. 1 hit.
[Graphical view ]
SMARTi SM00220. S_TKc. 1 hit.
SM00165. UBA. 1 hit.
[Graphical view ]
SUPFAMi SSF103243. SSF103243. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEi PS50032. KA1. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
PS50030. UBA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "MARK4, homologue of MARK1, MARK2 and MARK3."
    Drewes G., Mandelkow E.M.
    Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Tissue: Brain.
  2. "Isolation of a novel human gene, MARKL1, homologous to MARK3 and its involvement in hepatocellular carcinogenesis."
    Kato T., Satoh S., Okabe H., Kitahara O., Ono K., Kihara C., Tanaka T., Tsunoda T., Yamaoka Y., Nakamura Y., Furukawa Y.
    Neoplasia 3:4-9(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), TISSUE SPECIFICITY.
    Tissue: Brain.
  3. "Neural progenitor-restricted isoform of MARKL1 gene is upregulated by 19q13 amplification in human glioblastoma."
    Beghini A., Magnani I., Roversi G., Piepoli T., DiTerlizzi S., Pollo B., Conti A.M.F., Cowell J.K., Finocchiaro G., Larizza L.
    Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Tissue: Brain.
  4. "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
    Nagase T., Nakayama M., Nakajima D., Kikuno R., Ohara O.
    DNA Res. 8:85-95(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Brain.
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Thyroid.
  6. "LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1."
    Lizcano J.M., Goeransson O., Toth R., Deak M., Morrice N.A., Boudeau J., Hawley S.A., Udd L., Maekelae T.P., Hardie D.G., Alessi D.R.
    EMBO J. 23:833-843(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: ENZYME REGULATION, PHOSPHORYLATION AT THR-214, MUTAGENESIS OF THR-214.
  7. "Control of AMPK-related kinases by USP9X and atypical Lys(29)/Lys(33)-linked polyubiquitin chains."
    Al-Hakim A.K., Zagorska A., Chapman L., Deak M., Peggie M., Alessi D.R.
    Biochem. J. 411:249-260(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: UBIQUITINATION, DEUBIQUITINATION BY USP9X.
  8. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  9. "Patterns of somatic mutation in human cancer genomes."
    Greenman C., Stephens P., Smith R., Dalgliesh G.L., Hunter C., Bignell G., Davies H., Teague J., Butler A., Stevens C., Edkins S., O'Meara S., Vastrik I., Schmidt E.E., Avis T., Barthorpe S., Bhamra G., Buck G.
    , Choudhury B., Clements J., Cole J., Dicks E., Forbes S., Gray K., Halliday K., Harrison R., Hills K., Hinton J., Jenkinson A., Jones D., Menzies A., Mironenko T., Perry J., Raine K., Richardson D., Shepherd R., Small A., Tofts C., Varian J., Webb T., West S., Widaa S., Yates A., Cahill D.P., Louis D.N., Goldstraw P., Nicholson A.G., Brasseur F., Looijenga L., Weber B.L., Chiew Y.-E., DeFazio A., Greaves M.F., Green A.R., Campbell P., Birney E., Easton D.F., Chenevix-Trench G., Tan M.-H., Khoo S.K., Teh B.T., Yuen S.T., Leung S.Y., Wooster R., Futreal P.A., Stratton M.R.
    Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANTS [LARGE SCALE ANALYSIS] GLN-377 AND CYS-418.

Entry informationi

Entry nameiMARK4_HUMAN
AccessioniPrimary (citable) accession number: Q96L34
Secondary accession number(s): Q8NG37
, Q96JG7, Q96SQ2, Q9BYD8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 28, 2003
Last sequence update: December 1, 2001
Last modified: July 9, 2014
This is version 134 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human and mouse protein kinases
    Human and mouse protein kinases: classification and index
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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