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Q96L21 (RL10L_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 99. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
60S ribosomal protein L10-like
Gene names
Name:RPL10L
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length214 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

May play a role in compensating for the inactivated X-linked gene during spermatogenesis. Ref.1

Tissue specificity

Testis specific. Ref.1

Miscellaneous

This gene has no introns in its coding regions, and therefore was most likely produced by retrotransposition of the original X-linked gene during evolution.

Sequence similarities

Belongs to the ribosomal protein L10e family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 21421460S ribosomal protein L10-like
PRO_0000147106

Sequences

Sequence LengthMass (Da)Tools
Q96L21 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 9119E2F8C40C2E37

FASTA21424,519
        10         20         30         40         50         60 
MGRRPARCYR YCKNKPYPKS RFCRGVPDAK IRIFDLGRKK AKVDEFPLGG HMVSDEYEQL 

        70         80         90        100        110        120 
SSEALEAARI CANKYMVKSC GRDGFHMRVR LHPFHVIRIN KMLSCAGADR LQTGMRGAFG 

       130        140        150        160        170        180 
KPQGTVARVH IGQVIMSIRT KLQNEEHVIE ALRRAKFKFP GRQKIHISKK WGFTKFNADE 

       190        200        210 
FEDMVAKKCL IPDGCGVKYV PSHGPLDKWR VLHS 

« Hide

References

« Hide 'large scale' references
[1]"Functional second genes generated by retrotransposition of the X-linked ribosomal protein genes."
Uechi T., Maeda N., Tanaka T., Kenmochi N.
Nucleic Acids Res. 30:5369-5375(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Testis.
[3]"Structures of the human and Drosophila 80S ribosome."
Anger A.M., Armache J.P., Berninghausen O., Habeck M., Subklewe M., Wilson D.N., Beckmann R.
Nature 497:80-85(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: STRUCTURE BY ELECTRON MICROSCOPY (5.0 ANGSTROMS) OF 80S RIBOSOME.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB063605 Genomic DNA. Translation: BAC19833.1.
AB063608 mRNA. Translation: BAC19835.1.
BC014310 mRNA. Translation: AAH14310.1.
BC066312 mRNA. Translation: AAH66312.1.
RefSeqNP_542784.1. NM_080746.2.
UniGeneHs.308332.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3J3Belectron microscopy5.00I1-214[»]
ProteinModelPortalQ96L21.
SMRQ96L21. Positions 2-214.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid126711. 72 interactions.
IntActQ96L21. 3 interactions.
MINTMINT-1140193.
STRING9606.ENSP00000298283.

PTM databases

PhosphoSiteQ96L21.

Polymorphism databases

DMDM57013008.

Proteomic databases

PaxDbQ96L21.
PeptideAtlasQ96L21.
PRIDEQ96L21.

Protocols and materials databases

DNASU140801.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000298283; ENSP00000298283; ENSG00000165496.
GeneID140801.
KEGGhsa:140801.
UCSCuc001wwg.3. human.

Organism-specific databases

CTD140801.
GeneCardsGC14M047120.
HGNCHGNC:17976. RPL10L.
HPAHPA011311.
neXtProtNX_Q96L21.
PharmGKBPA34662.
GenAtlasSearch...

Phylogenomic databases

eggNOGCOG0197.
HOGENOMHOG000223754.
HOVERGENHBG002287.
InParanoidQ96L21.
KOK02866.
OMAAGRMGYH.
OrthoDBEOG76MK97.
PhylomeDBQ96L21.
TreeFamTF300082.

Gene expression databases

BgeeQ96L21.
CleanExHS_RPL10L.
GenevestigatorQ96L21.

Family and domain databases

Gene3D3.90.1170.10. 1 hit.
InterProIPR001197. Ribosomal_L10e.
IPR016180. Ribosomal_L10e/L16.
IPR018255. Ribosomal_L10e_CS.
[Graphical view]
PfamPF00252. Ribosomal_L16. 1 hit.
[Graphical view]
PIRSFPIRSF005590. Ribosomal_L10. 1 hit.
SUPFAMSSF54686. SSF54686. 1 hit.
TIGRFAMsTIGR00279. L10e. 1 hit.
PROSITEPS01257. RIBOSOMAL_L10E. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GeneWikiRPL10L.
GenomeRNAi140801.
NextBio84401.
PROQ96L21.

Entry information

Entry nameRL10L_HUMAN
AccessionPrimary (citable) accession number: Q96L21
Secondary accession number(s): Q8IUD1
Entry history
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: January 23, 2007
Last modified: February 19, 2014
This is version 99 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Human chromosome 14

Human chromosome 14: entries, gene names and cross-references to MIM