Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

LLLL and CFNLAS motif-containing protein 1

Gene

LLCFC1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
LLLL and CFNLAS motif-containing protein 1Imported
Alternative name(s):
MSSP-binding protein CTM-11 Publication
Gene namesi
Name:LLCFC1Imported
Synonyms:C7orf34
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000165131.6
HGNCiHGNC:21750 LLCFC1
neXtProtiNX_Q96L11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134972511

Polymorphism and mutation databases

BioMutaiC7orf34

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_000001954629 – 122LLLL and CFNLAS motif-containing protein 1Add BLAST94

Proteomic databases

PaxDbiQ96L11
PeptideAtlasiQ96L11
PRIDEiQ96L11

Expressioni

Gene expression databases

BgeeiENSG00000165131
CleanExiHS_C7orf34
GenevisibleiQ96L11 HS

Interactioni

Protein-protein interaction databases

BioGridi1264381 interactor.
IntActiQ96L11 1 interactor.
STRINGi9606.ENSP00000386450

Structurei

3D structure databases

ProteinModelPortaliQ96L11
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410JE8V Eukaryota
ENOG411162G LUCA
HOGENOMiHOG000111591
HOVERGENiHBG081126
InParanoidiQ96L11
OrthoDBiEOG091G0PSV
PhylomeDBiQ96L11
TreeFamiTF338373

Family and domain databases

InterProiView protein in InterPro
IPR031684 DUF4717
PANTHERiPTHR37348 PTHR37348, 1 hit
PfamiView protein in Pfam
PF15838 DUF4717, 1 hit

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q96L11-1) [UniParc]FASTAAdd to basket
Also known as: CTM-1beta

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MPPLAPQLCR AVFLVPILLL LQVKPLNGSP GPKDGSQTEK TPSADQNQEQ
60 70 80 90 100
FEEHFVASSV GEMWQVVDMA QQEEDQSSKT AAVHKHSFHL SFCFSLASVM
110 120
VFSGGPLRRT FPNIQLCFML TH
Length:122
Mass (Da):13,527
Last modified:December 1, 2001 - v1
Checksum:i460E99776D0F4C8F
GO
Isoform 2 (identifier: Q96L11-2) [UniParc]FASTAAdd to basket
Also known as: CTM-1alpha

The sequence of this isoform differs from the canonical sequence as follows:
     45-46: DQ → GS
     47-122: Missing.

Show »
Length:46
Mass (Da):4,768
Checksum:i930966E755314E7A
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_01474345 – 46DQ → GS in isoform 2. 1 Publication2
Alternative sequenceiVSP_01474447 – 122Missing in isoform 2. 1 PublicationAdd BLAST76

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB083483 mRNA Translation: BAB88941.1
AB083484 mRNA Translation: BAB88942.1
AC099652 Genomic DNA No translation available.
CH236959 Genomic DNA Translation: EAL23778.1
BC014596 mRNA Translation: AAH14596.1
RefSeqiNP_849151.2, NM_178829.4
UniGeneiHs.239676

Genome annotation databases

EnsembliENST00000409607; ENSP00000386450; ENSG00000165131
ENST00000458732; ENSP00000401055; ENSG00000165131
GeneIDi135927
KEGGihsa:135927
UCSCiuc003wca.3 human [Q96L11-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiLCFC1_HUMAN
AccessioniPrimary (citable) accession number: Q96L11
Secondary accession number(s): A4D2H8, C9JTW1, Q8TDV6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: December 1, 2001
Last modified: February 28, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome