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Protein

Uncharacterized protein C7orf34

Gene

C7orf34

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

BioCyciZFISH:ENSG00000165131-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C7orf34
Alternative name(s):
MSSP-binding protein CTM-1
Gene namesi
Name:C7orf34
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

HGNCiHGNC:21750. C7orf34.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134972511.

Polymorphism and mutation databases

BioMutaiC7orf34.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_000001954629 – 122Uncharacterized protein C7orf34Add BLAST94

Proteomic databases

PaxDbiQ96L11.
PRIDEiQ96L11.

Expressioni

Gene expression databases

BgeeiENSG00000165131.
CleanExiHS_C7orf34.
GenevisibleiQ96L11. HS.

Organism-specific databases

HPAiHPA040192.

Interactioni

Protein-protein interaction databases

BioGridi126438. 1 interactor.
IntActiQ96L11. 1 interactor.
MINTiMINT-1481746.
STRINGi9606.ENSP00000386450.

Structurei

3D structure databases

ProteinModelPortaliQ96L11.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410JE8V. Eukaryota.
ENOG411162G. LUCA.
HOGENOMiHOG000111591.
HOVERGENiHBG081126.
InParanoidiQ96L11.
OrthoDBiEOG091G0PSV.
PhylomeDBiQ96L11.
TreeFamiTF338373.

Family and domain databases

InterProiIPR031684. DUF4717.
[Graphical view]
PfamiPF15838. DUF4717. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q96L11-1) [UniParc]FASTAAdd to basket
Also known as: CTM-1beta

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MPPLAPQLCR AVFLVPILLL LQVKPLNGSP GPKDGSQTEK TPSADQNQEQ
60 70 80 90 100
FEEHFVASSV GEMWQVVDMA QQEEDQSSKT AAVHKHSFHL SFCFSLASVM
110 120
VFSGGPLRRT FPNIQLCFML TH
Length:122
Mass (Da):13,527
Last modified:December 1, 2001 - v1
Checksum:i460E99776D0F4C8F
GO
Isoform 2 (identifier: Q96L11-2) [UniParc]FASTAAdd to basket
Also known as: CTM-1alpha

The sequence of this isoform differs from the canonical sequence as follows:
     45-46: DQ → GS
     47-122: Missing.

Show »
Length:46
Mass (Da):4,768
Checksum:i930966E755314E7A
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_01474345 – 46DQ → GS in isoform 2. 1 Publication2
Alternative sequenceiVSP_01474447 – 122Missing in isoform 2. 1 PublicationAdd BLAST76

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB083483 mRNA. Translation: BAB88941.1.
AB083484 mRNA. Translation: BAB88942.1.
AC099652 Genomic DNA. No translation available.
CH236959 Genomic DNA. Translation: EAL23778.1.
BC014596 mRNA. Translation: AAH14596.1.
RefSeqiNP_849151.2. NM_178829.4.
UniGeneiHs.239676.

Genome annotation databases

EnsembliENST00000409607; ENSP00000386450; ENSG00000165131.
ENST00000458732; ENSP00000401055; ENSG00000165131.
GeneIDi135927.
KEGGihsa:135927.
UCSCiuc003wca.3. human. [Q96L11-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB083483 mRNA. Translation: BAB88941.1.
AB083484 mRNA. Translation: BAB88942.1.
AC099652 Genomic DNA. No translation available.
CH236959 Genomic DNA. Translation: EAL23778.1.
BC014596 mRNA. Translation: AAH14596.1.
RefSeqiNP_849151.2. NM_178829.4.
UniGeneiHs.239676.

3D structure databases

ProteinModelPortaliQ96L11.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi126438. 1 interactor.
IntActiQ96L11. 1 interactor.
MINTiMINT-1481746.
STRINGi9606.ENSP00000386450.

Polymorphism and mutation databases

BioMutaiC7orf34.

Proteomic databases

PaxDbiQ96L11.
PRIDEiQ96L11.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000409607; ENSP00000386450; ENSG00000165131.
ENST00000458732; ENSP00000401055; ENSG00000165131.
GeneIDi135927.
KEGGihsa:135927.
UCSCiuc003wca.3. human. [Q96L11-1]

Organism-specific databases

CTDi135927.
GeneCardsiC7orf34.
HGNCiHGNC:21750. C7orf34.
HPAiHPA040192.
neXtProtiNX_Q96L11.
PharmGKBiPA134972511.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410JE8V. Eukaryota.
ENOG411162G. LUCA.
HOGENOMiHOG000111591.
HOVERGENiHBG081126.
InParanoidiQ96L11.
OrthoDBiEOG091G0PSV.
PhylomeDBiQ96L11.
TreeFamiTF338373.

Enzyme and pathway databases

BioCyciZFISH:ENSG00000165131-MONOMER.

Miscellaneous databases

GenomeRNAii135927.
PROiQ96L11.

Gene expression databases

BgeeiENSG00000165131.
CleanExiHS_C7orf34.
GenevisibleiQ96L11. HS.

Family and domain databases

InterProiIPR031684. DUF4717.
[Graphical view]
PfamiPF15838. DUF4717. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCG034_HUMAN
AccessioniPrimary (citable) accession number: Q96L11
Secondary accession number(s): A4D2H8, C9JTW1, Q8TDV6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: December 1, 2001
Last modified: November 2, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.