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Protein

Spermatogenesis-associated protein 17

Gene

SPATA17

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Keywords - Ligandi

Calmodulin-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Spermatogenesis-associated protein 17
Gene namesi
Name:SPATA17
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:25184. SPATA17.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA144596270.

Polymorphism and mutation databases

BioMutaiSPATA17.
DMDMi74751996.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 361361Spermatogenesis-associated protein 17PRO_0000265933Add
BLAST

Proteomic databases

PaxDbiQ96L03.
PeptideAtlasiQ96L03.
PRIDEiQ96L03.

PTM databases

iPTMnetiQ96L03.
PhosphoSiteiQ96L03.

Expressioni

Gene expression databases

BgeeiENSG00000162814.
CleanExiHS_SPATA17.
ExpressionAtlasiQ96L03. baseline and differential.
GenevisibleiQ96L03. HS.

Organism-specific databases

HPAiHPA030099.

Interactioni

Protein-protein interaction databases

BioGridi126095. 2 interactions.
STRINGi9606.ENSP00000355900.

Structurei

3D structure databases

ProteinModelPortaliQ96L03.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini32 – 6130IQ 1PROSITE-ProRule annotationAdd
BLAST
Domaini55 – 8430IQ 2PROSITE-ProRule annotationAdd
BLAST
Domaini91 – 12030IQ 3PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 3 IQ domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG410IKZ3. Eukaryota.
ENOG41100C4. LUCA.
GeneTreeiENSGT00390000011270.
HOGENOMiHOG000273860.
HOVERGENiHBG093989.
InParanoidiQ96L03.
OMAiNDNMFLP.
OrthoDBiEOG091G12SS.
PhylomeDBiQ96L03.
TreeFamiTF329213.

Family and domain databases

InterProiIPR000048. IQ_motif_EF-hand-BS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00612. IQ. 3 hits.
[Graphical view]
SMARTiSM00015. IQ. 3 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS50096. IQ. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q96L03-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATLARLQAR SSTVGNQYYF RNSVVDPFRK KENDAAVKIQ SWFRGCQVRA
60 70 80 90 100
YIRHLNRIVT IIQKWWRSFL GRKQYQLTVQ VAYYTMMMNL YNAMAVRIQR
110 120 130 140 150
RWRGYRVRKY LFNYYYLKEY LKVVSETNDA IRKALEEFAE MKEREEKKAN
160 170 180 190 200
LEREEKKRDY QARKMHYLLS TKQIPGIYNS PFRKEPDPWE LQLQKAKPLT
210 220 230 240 250
HRRPKVKQKD STSLTDWLAC TSARSFPRSE ILPPINRKQC QGPFRDITEV
260 270 280 290 300
LEQRYRPLEP TLRVAEPIDE LKLAREELRR EEWLQNVNDN MFLPFSSYHK
310 320 330 340 350
NEKYIPSMHL SSKYGPISYK EQFRSENPKK WICDKDFQTV LPSFELFSKY
360
GKLYSKAGQI V
Length:361
Mass (Da):43,499
Last modified:December 1, 2001 - v1
Checksum:i31575B9E51AFF8A5
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti16 – 161N → S.
Corresponds to variant rs34652544 [ dbSNP | Ensembl ].
VAR_051382

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY963797 mRNA. Translation: AAY33662.1.
AK098591 mRNA. Translation: BAC05343.1.
AL445428, AC097061, AL354659 Genomic DNA. Translation: CAH70554.1.
AL354659, AC097061, AL445428 Genomic DNA. Translation: CAH70665.1.
CH471100 Genomic DNA. Translation: EAW93332.1.
BC014608 mRNA. Translation: AAH14608.1.
CCDSiCCDS1519.1.
RefSeqiNP_620151.1. NM_138796.3.
XP_005273109.1. XM_005273052.1.
UniGeneiHs.171130.
Hs.665237.

Genome annotation databases

EnsembliENST00000366933; ENSP00000355900; ENSG00000162814.
GeneIDi128153.
KEGGihsa:128153.
UCSCiuc001hlh.2. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY963797 mRNA. Translation: AAY33662.1.
AK098591 mRNA. Translation: BAC05343.1.
AL445428, AC097061, AL354659 Genomic DNA. Translation: CAH70554.1.
AL354659, AC097061, AL445428 Genomic DNA. Translation: CAH70665.1.
CH471100 Genomic DNA. Translation: EAW93332.1.
BC014608 mRNA. Translation: AAH14608.1.
CCDSiCCDS1519.1.
RefSeqiNP_620151.1. NM_138796.3.
XP_005273109.1. XM_005273052.1.
UniGeneiHs.171130.
Hs.665237.

3D structure databases

ProteinModelPortaliQ96L03.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi126095. 2 interactions.
STRINGi9606.ENSP00000355900.

PTM databases

iPTMnetiQ96L03.
PhosphoSiteiQ96L03.

Polymorphism and mutation databases

BioMutaiSPATA17.
DMDMi74751996.

Proteomic databases

PaxDbiQ96L03.
PeptideAtlasiQ96L03.
PRIDEiQ96L03.

Protocols and materials databases

DNASUi128153.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000366933; ENSP00000355900; ENSG00000162814.
GeneIDi128153.
KEGGihsa:128153.
UCSCiuc001hlh.2. human.

Organism-specific databases

CTDi128153.
GeneCardsiSPATA17.
HGNCiHGNC:25184. SPATA17.
HPAiHPA030099.
MIMi611032. gene.
neXtProtiNX_Q96L03.
PharmGKBiPA144596270.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IKZ3. Eukaryota.
ENOG41100C4. LUCA.
GeneTreeiENSGT00390000011270.
HOGENOMiHOG000273860.
HOVERGENiHBG093989.
InParanoidiQ96L03.
OMAiNDNMFLP.
OrthoDBiEOG091G12SS.
PhylomeDBiQ96L03.
TreeFamiTF329213.

Miscellaneous databases

ChiTaRSiSPATA17. human.
GenomeRNAii128153.
PROiQ96L03.
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000162814.
CleanExiHS_SPATA17.
ExpressionAtlasiQ96L03. baseline and differential.
GenevisibleiQ96L03. HS.

Family and domain databases

InterProiIPR000048. IQ_motif_EF-hand-BS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00612. IQ. 3 hits.
[Graphical view]
SMARTiSM00015. IQ. 3 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS50096. IQ. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSPT17_HUMAN
AccessioniPrimary (citable) accession number: Q96L03
Secondary accession number(s): A5D6N2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: December 1, 2001
Last modified: September 7, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.