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Protein

Spermatogenesis-associated protein 17

Gene

SPATA17

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionCalmodulin-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Spermatogenesis-associated protein 17
Gene namesi
Name:SPATA17
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000162814.10
HGNCiHGNC:25184 SPATA17
MIMi611032 gene
neXtProtiNX_Q96L03

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Organism-specific databases

DisGeNETi128153
OpenTargetsiENSG00000162814
PharmGKBiPA144596270

Polymorphism and mutation databases

BioMutaiSPATA17
DMDMi74751996

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002659331 – 361Spermatogenesis-associated protein 17Add BLAST361

Proteomic databases

MaxQBiQ96L03
PaxDbiQ96L03
PeptideAtlasiQ96L03
PRIDEiQ96L03

PTM databases

iPTMnetiQ96L03
PhosphoSitePlusiQ96L03

Expressioni

Gene expression databases

BgeeiENSG00000162814
CleanExiHS_SPATA17
ExpressionAtlasiQ96L03 baseline and differential
GenevisibleiQ96L03 HS

Organism-specific databases

HPAiHPA030099

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CALM3P0DP254EBI-13322423,EBI-397435

GO - Molecular functioni

Protein-protein interaction databases

BioGridi126095, 2 interactors
IntActiQ96L03, 1 interactor
STRINGi9606.ENSP00000355900

Structurei

3D structure databases

ProteinModelPortaliQ96L03
SMRiQ96L03
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 61IQ 1PROSITE-ProRule annotationAdd BLAST30
Domaini55 – 84IQ 2PROSITE-ProRule annotationAdd BLAST30
Domaini91 – 120IQ 3PROSITE-ProRule annotationAdd BLAST30

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG410IKZ3 Eukaryota
ENOG41100C4 LUCA
GeneTreeiENSGT00390000011270
HOGENOMiHOG000273860
HOVERGENiHBG093989
InParanoidiQ96L03
OMAiDNMFLPF
OrthoDBiEOG091G12SS
PhylomeDBiQ96L03
TreeFamiTF329213

Family and domain databases

InterProiView protein in InterPro
IPR000048 IQ_motif_EF-hand-BS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00612 IQ, 3 hits
SMARTiView protein in SMART
SM00015 IQ, 3 hits
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50096 IQ, 3 hits

Sequencei

Sequence statusi: Complete.

Q96L03-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATLARLQAR SSTVGNQYYF RNSVVDPFRK KENDAAVKIQ SWFRGCQVRA
60 70 80 90 100
YIRHLNRIVT IIQKWWRSFL GRKQYQLTVQ VAYYTMMMNL YNAMAVRIQR
110 120 130 140 150
RWRGYRVRKY LFNYYYLKEY LKVVSETNDA IRKALEEFAE MKEREEKKAN
160 170 180 190 200
LEREEKKRDY QARKMHYLLS TKQIPGIYNS PFRKEPDPWE LQLQKAKPLT
210 220 230 240 250
HRRPKVKQKD STSLTDWLAC TSARSFPRSE ILPPINRKQC QGPFRDITEV
260 270 280 290 300
LEQRYRPLEP TLRVAEPIDE LKLAREELRR EEWLQNVNDN MFLPFSSYHK
310 320 330 340 350
NEKYIPSMHL SSKYGPISYK EQFRSENPKK WICDKDFQTV LPSFELFSKY
360
GKLYSKAGQI V
Length:361
Mass (Da):43,499
Last modified:December 1, 2001 - v1
Checksum:i31575B9E51AFF8A5
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_05138216N → S. Corresponds to variant dbSNP:rs34652544Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY963797 mRNA Translation: AAY33662.1
AK098591 mRNA Translation: BAC05343.1
AC097061 Genomic DNA No translation available.
AL354659 Genomic DNA No translation available.
AL445428 Genomic DNA No translation available.
CH471100 Genomic DNA Translation: EAW93332.1
BC014608 mRNA Translation: AAH14608.1
CCDSiCCDS1519.1
RefSeqiNP_620151.1, NM_138796.3
XP_005273109.1, XM_005273052.1
UniGeneiHs.171130
Hs.665237

Genome annotation databases

EnsembliENST00000366933; ENSP00000355900; ENSG00000162814
GeneIDi128153
KEGGihsa:128153
UCSCiuc001hlh.2 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiSPT17_HUMAN
AccessioniPrimary (citable) accession number: Q96L03
Secondary accession number(s): A5D6N2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: December 1, 2001
Last modified: May 23, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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Main funding by: National Institutes of Health