Q96KY6 (Q96KY6_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
ADCY4 protein EMBL AAH15982.2

Gene names

Name:

ADCY4 EMBL AAH15982.2

Organism

Homo sapiens (Human) EMBL AAH15982.2

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	130 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. RuleBase RU000405

Ontologies

Keywords
Ligand	Nucleotide-binding SAAS SAAS001054
Molecular function	Lyase RuleBase RU000405 SAAS SAAS001054
Gene Ontology (GO)
Biological_process	adenylate cyclase-modulating G-protein coupled receptor signaling pathway Inferred from electronic annotation. Source: Compara cyclic nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro intracellular signal transduction Inferred from electronic annotation. Source: InterPro
Cellular_component	dendrite Inferred from electronic annotation. Source: Compara intracellular Inferred from electronic annotation. Source: Compara
Molecular_function	nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW phosphorus-oxygen lyase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAH15982.2

Sequences

	Sequence		Length	Mass (Da)
	Q96KY6 [UniParc]. Last modified March 1, 2004. Version 2. Checksum: 9858BAA5B45FC896	FASTA	130	13,987
	10 20 30 40 50 60 DAERSCSHLG TMVEFAVALG SKLDVINKHS FNNFRLRVGL NHGPVVAGVI GAQKPQYDIW 70 80 90 100 110 120 GNTVNVASRM ESTGVLGKIQ VTEETAWALQ SLGYTCYSRG VIKVKGKGQL CTYFLNTDLT 130 RTGPPSATLG

References

[1]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Lung EMBL AAH15982.2.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC015982 mRNA. Translation: AAH15982.2.
IPI	IPI00465156.
UniGene	Hs.443428.
3D structure databases
HSSP	HSSP built from PDB template 1AB8 based on UniProtKB P26769.
ProteinModelPortal	Q96KY6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q96KY6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
PharmGKB	PA24562.
Gene expression databases
ArrayExpress	Q96KY6.
Bgee	Q96KY6.
Family and domain databases
Gene3D	3.30.70.1230. 1 hit.
InterPro	IPR001054. A/G_cyclase. IPR018297. A/G_cyclase_CS. [Graphical view]
Pfam	PF00211. Guanylate_cyc. 1 hit. [Graphical view]
SMART	SM00044. CYCc. 1 hit. [Graphical view]
SUPFAM	SSF55073. A/G_cyclase. 1 hit.
PROSITE	PS00452. GUANYLATE_CYCLASE_1. 1 hit. PS50125. GUANYLATE_CYCLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	13646206.

Entry information

Entry name

Q96KY6_HUMAN

Accession

Primary (citable) accession number: Q96KY6

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	March 1, 2004
Last modified:	April 3, 2013
This is version 69 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.