Reviewed, UniProtKB/Swiss-Prot Q96KW9 (CM028_HUMAN)

Names and origin

Protein names

Recommended name:
    Putative uncharacterized protein C13orf28

Gene names

Name:

C13orf28

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	195 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location

Secreted Potential.

Ontologies

Keywords
Cellular component	Secreted
Coding sequence diversity	Polymorphism
Domain	Signal
PTM	Glycoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 24	24	Potential
	Chain	25 – 195	171	Putative uncharacterized protein C13orf28		PRO_0000274330
Amino acid modifications
	Glycosylation	62	1	N-linked (GlcNAc...) Potential
	Glycosylation	159	1	N-linked (GlcNAc...) Potential
Natural variations
	Natural variant	25	1	R → W in a colorectal cancer sample; somatic mutation. Ref.3		VAR_035675
	Natural variant	111	1	V → D: dbSNP rs10816. Ref.2		VAR_030260

Sequences

	Sequence		Length	Mass (Da)
	Q96KW9-1 [UniParc]. Last modified February 6, 2007. Version 2. Checksum: 09E285617F560FD8	FASTA	195	21,466
	10 20 30 40 50 60 MAVSQGDGTL CFVLLLCCWQ ETELRPRTVI PGSPTEIPFS SKQEDMSELL DEILVQEILD 70 80 90 100 110 120 LNKTTPSEMP STASTLSTPL HAGIDENYQA GGSENYHELL ENLQFSPGIE VKISNDEANA 130 140 150 160 170 180 NANLHGDPSE NYRGPQVSPG SEKSVSSKEK NSKNTQYENL SILDQILQNI GRSSGNIFHK 190 EQQRTSAQRR SQGSQ

References

[1]	"The DNA sequence and analysis of human chromosome 13." Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L., Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S., Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P., Ambrose K.D., Andrews D.T. , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P., Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C., Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P., Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L., Frankish A.G., Frankland J., French L., Garner P., Garnett J., Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M., Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D., Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D., Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S., Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S., Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Beck S., Bentley D.R., Rogers J., Ross M.T. Nature 428:522-528(2004) [PubMed: 15057823] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ASP-111. Tissue: Testis.
[3]	"The consensus coding sequences of human breast and colorectal cancers." Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., Dawson D., Willson J.K.V. , Gazdar A.F., Hartigan J., Wu L., Liu C., Parmigiani G., Park B.H., Bachman K.E., Papadopoulos N., Vogelstein B., Kinzler K.W., Velculescu V.E. Science 314:268-274(2006) [PubMed: 16959974] [Abstract] Cited for: VARIANT [LARGE SCALE ANALYSIS] TRP-25.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL160033 Genomic DNA. Translation: CAI14451.1. BC016750 mRNA. Translation: AAH16750.1.
IPI	IPI00747019.
RefSeq	NP_660291.1.
UniGene	Hs.97592
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	Q96KW9.
Genome annotation databases
Ensembl	ENST00000283550; ENSP00000283550; ENSG00000153498; Homo sapiens. [Genome view]
GeneID	122258.
KEGG	hsa:122258.
NMPDR	fig|9606.3.peg.9100.
UCSC	uc001vsd.1. human.
Organism-specific databases
CTD	122258.
GeneCards	GC13P112079.
HGNC	HGNC:29575. C13orf28.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q96KW9.
OrthoDB	EOG9XH2JZ
Gene expression databases
ArrayExpress	Q96KW9.
Bgee	Q96KW9.
CleanEx	HS_C13orf28.
Genevestigator	Q96KW9.
Family and domain databases
ProtoNet	Search...
Other Resources
NextBio	80869.

Entry information

Entry name

CM028_HUMAN

Accession

Primary (citable) accession number: Q96KW9
Secondary accession number(s): Q5T8L1

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	November 24, 2009
This is version 45 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.