Unreviewed, UniProtKB/TrEMBL Q96KU4 (Q96KU4_HUMAN)

Names and origin

Protein names

Submitted name:
    Gephyrin EMBL CAC81240.1

Gene names

Name:

GPHRYN EMBL CAC81240.1

Organism

Homo sapiens (Human) EMBL CAC81240.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	736 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Biological process	Mo-molybdopterin cofactor biosynthetic process Inferred from electronic annotation. Source: InterPro establishment of synaptic specificity at neuromuscular junction Inferred from electronic annotation. Source: Compara
Cellular component	intracellular Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q96KU4-1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: E53D245C07BCD4FD	FASTA	736	79,776
	10 20 30 40 50 60 MATEGMILTN HDHQIRVGVL TVSDSCFRNL AEDRSGINLK DLVQDPSLLG GTISAYKIVP 70 80 90 100 110 120 DEIEEIKETL IDWCDEKELN LILTTGGTGF APRDVTPEAT KEVIEREAPG MALAMLMGSL 130 140 150 160 170 180 NVTPLGMLSR PVCGIRGKTL IINLPGSKKG SQECFQFILP ALPHAIDLLR DAIVKVKEVH 190 200 210 220 230 240 DELEDLPSPP PPLSPPPTTS PHKQTEDKGV QCEEEEEEKK DSGVASTEDS SSSHITAAAI 250 260 270 280 290 300 AAKIPDSIIS RGVQVLPRDT VSLSTTPSES PRAQATSRLS TASCPTPKVQ SRCSSKENIL 310 320 330 340 350 360 RASHSAVDIT KVARRHRMSP FPLTSMDKAF ITVLEMTPVL GTEIINYRDG MGRVLAQDVY 370 380 390 400 410 420 AKDNLPPFPA SVKDGYAVRA ADGPGDRFII GESQAGEQPT QTVMPGQVMR VTTGAPIPCG 430 440 450 460 470 480 ADAVVQVEDT ELIRESDDGT EELEVRILVQ ARPGQDIRPI GHDIKRGECV LAKGTHMGPS 490 500 510 520 530 540 EIGLLATVGV TEVEVNKFPV VAVMSTGNEL LNPEDDLLPG KIRDSNRSTL LATIQEHGYP 550 560 570 580 590 600 TINLGIVGDN PDDLLNALNE GISRADVIIT SGGVSMGEKD YLKQVLDIDL HAQIHFGRVF 610 620 630 640 650 660 MKPGLPTTFA TLDIDGVRKI IFALPGNPVS AVVTCNLFVV PALRKMQGIL DPRPTIIKAR 670 680 690 700 710 720 LSCDVKLDPR PEYHRCILTW HHQEPLPWAQ STGNQMSSRL MSMRSANGLL MLPPKTEQYV 730 ELHKGEVVDV MVIGRL

References

[1]	"Autoimmunity to gephyrin in Stiff-Man syndrome." Butler M.H., Hayashi A., Okoshi N., Villmann C., Becker C.M., Feng G., De Camilli P., Solimena M. Neuron 26:307-312(2000) [PubMed: 10839351] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Hippocampus EMBL CAC81240.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ272033 mRNA. Translation: CAC81240.1.
IPI	IPI00016006.
UniGene	Hs.208765
3D structure databases
HSSP	HSSP built from PDB template 1JLJ based on UniProtKB Q9NQX3.
SMR	Q96KU4. Positions 13-181, 318-736.
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000171723. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:15465. GPHN.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q96KU4.
Gene expression databases
ArrayExpress	Q96KU4.
Bgee	Q96KU4.
Family and domain databases
InterPro	IPR008284. MoCF_biosynth_CS. IPR005111. MoeA_C_domain_IV. IPR005110. MoeA_N. IPR001453. Mopterin_bd. [Graphical view]
Gene3D	G3DSA:3.40.980.10. MPT_bd. 2 hits.
Pfam	PF00994. MoCF_biosynth. 2 hits. PF03454. MoeA_C. 1 hit. PF03453. MoeA_N. 1 hit. [Graphical view]
ProDom	PD002460. MoCF_biosynth. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00177. molyb_syn. 2 hits.
PROSITE	PS01078. MOCF_BIOSYNTHESIS_1. 1 hit. PS01079. MOCF_BIOSYNTHESIS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q96KU4_HUMAN

Accession

Primary (citable) accession number: Q96KU4

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	March 3, 2009
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)