Q96KU4 (Q96KU4_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Gephyrin EMBL CAC81240.1

Gene names

Name:

GPHRYN EMBL CAC81240.1

Organism

Homo sapiens (Human) EMBL CAC81240.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	736 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological process	Mo-molybdopterin cofactor biosynthetic process Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q96KU4 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: E53D245C07BCD4FD	FASTA	736	79,776
	10 20 30 40 50 60 MATEGMILTN HDHQIRVGVL TVSDSCFRNL AEDRSGINLK DLVQDPSLLG GTISAYKIVP 70 80 90 100 110 120 DEIEEIKETL IDWCDEKELN LILTTGGTGF APRDVTPEAT KEVIEREAPG MALAMLMGSL 130 140 150 160 170 180 NVTPLGMLSR PVCGIRGKTL IINLPGSKKG SQECFQFILP ALPHAIDLLR DAIVKVKEVH 190 200 210 220 230 240 DELEDLPSPP PPLSPPPTTS PHKQTEDKGV QCEEEEEEKK DSGVASTEDS SSSHITAAAI 250 260 270 280 290 300 AAKIPDSIIS RGVQVLPRDT VSLSTTPSES PRAQATSRLS TASCPTPKVQ SRCSSKENIL 310 320 330 340 350 360 RASHSAVDIT KVARRHRMSP FPLTSMDKAF ITVLEMTPVL GTEIINYRDG MGRVLAQDVY 370 380 390 400 410 420 AKDNLPPFPA SVKDGYAVRA ADGPGDRFII GESQAGEQPT QTVMPGQVMR VTTGAPIPCG 430 440 450 460 470 480 ADAVVQVEDT ELIRESDDGT EELEVRILVQ ARPGQDIRPI GHDIKRGECV LAKGTHMGPS 490 500 510 520 530 540 EIGLLATVGV TEVEVNKFPV VAVMSTGNEL LNPEDDLLPG KIRDSNRSTL LATIQEHGYP 550 560 570 580 590 600 TINLGIVGDN PDDLLNALNE GISRADVIIT SGGVSMGEKD YLKQVLDIDL HAQIHFGRVF 610 620 630 640 650 660 MKPGLPTTFA TLDIDGVRKI IFALPGNPVS AVVTCNLFVV PALRKMQGIL DPRPTIIKAR 670 680 690 700 710 720 LSCDVKLDPR PEYHRCILTW HHQEPLPWAQ STGNQMSSRL MSMRSANGLL MLPPKTEQYV 730 ELHKGEVVDV MVIGRL

References

[1]	"Autoimmunity to gephyrin in Stiff-Man syndrome." Butler M.H., Hayashi A., Okoshi N., Villmann C., Becker C.M., Feng G., De Camilli P., Solimena M. Neuron 26:307-312(2000) [PubMed: 10839351] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Hippocampus EMBL CAC81240.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ272033 mRNA. Translation: CAC81240.1.
IPI	IPI00016006.
UniGene	Hs.208765.
3D structure databases
HSSP	HSSP built from PDB template 1JLJ based on UniProtKB Q9NQX3.
ProteinModelPortal	Q96KU4.
SMR	Q96KU4. Positions 13-181, 318-736.
ModBase	Search...
Protein-protein interaction databases
STRING	Q96KU4.
Proteomic databases
PRIDE	Q96KU4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
eggNOG	prNOG05615.
HOVERGEN	HBG005828.
Gene expression databases
ArrayExpress	Q96KU4.
Family and domain databases
InterPro	IPR020817. Mo_cofactor_synthesis. IPR008284. MoCF_biosynth_CS. IPR005111. MoeA_C_domain_IV. IPR005110. MoeA_linker/N. IPR001453. Mopterin-bd. [Graphical view]
Gene3D	G3DSA:2.40.340.10. G3DSA:2.40.340.10. 1 hit. G3DSA:3.40.980.10. MPT_bd. 2 hits.
Pfam	PF00994. MoCF_biosynth. 2 hits. PF03454. MoeA_C. 1 hit. PF03453. MoeA_N. 1 hit. [Graphical view]
SMART	SM00852. MoCF_biosynth. 2 hits. [Graphical view]
SUPFAM	SSF53218. MoCF_biosynth. 2 hits. SSF63867. MoeA_C. 1 hit. SSF63882. MoeA_N. 1 hit.
TIGRFAMs	TIGR00177. Molyb_syn. 2 hits.
PROSITE	PS01078. MOCF_BIOSYNTHESIS_1. 1 hit. PS01079. MOCF_BIOSYNTHESIS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q96KU4_HUMAN

Accession

Primary (citable) accession number: Q96KU4

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	November 16, 2011
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.