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Protein
Submitted name:

cDNA FLJ14389 fis, clone HEMBA1002876

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • ADP-sugar diphosphatase activity Source: UniProtKB
  • calcium activated cation channel activity Source: UniProtKB

GO - Biological processi

  • cation transport Source: UniProtKB

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ14389 fis, clone HEMBA1002876Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  • intracellular Source: UniProtKB

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31842.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500432191721 – 350Sequence analysisAdd BLAST330

Proteomic databases

PaxDbiQ96KB3.
PeptideAtlasiQ96KB3.
PRIDEiQ96KB3.

Expressioni

Gene expression databases

GenevisibleiQ96KB3. HS.

Structurei

3D structure databases

ProteinModelPortaliQ96KB3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini178 – 334Nudix hydrolaseInterPro annotationAdd BLAST157

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili232 – 259Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG4195. Eukaryota.
ENOG410XPYY. LUCA.
HOVERGENiHBG052693.
KOiK13988.

Family and domain databases

InterProiView protein in InterPro
IPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
PfamiView protein in Pfam
PF00293. NUDIX. 1 hit.
SUPFAMiSSF55811. SSF55811. 1 hit.
PROSITEiView protein in PROSITE
PS51462. NUDIX. 1 hit.

Sequencei

Sequence statusi: Complete.

Q96KB3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGRLLGKAL AAVSLSLALA SVTIRSSRCR GIQAFRNSFS SSWFHLNTNV
60 70 80 90 100
MSGSNGSKEN SHNKARTSPY PGSKVERSQV PNEKVGWLVE WQDYKPVEYT
110 120 130 140 150
AVSVLAGPRW ADPQISESNF SPKFNEKDGH VERKSKNGLY EIENGRPRNP
160 170 180 190 200
AGRTGLVGRG LLGRWGPNHA ADPIITRWKR DSSGNKIMHP VSGKHILQFV
210 220 230 240 250
AIKRKDCGEW AIPGGMVDPG EKISATLKRE FGEEALNSLQ KTSAEKREIE
260 270 280 290 300
EKLHKLFSQD HLVIYKGYVD DPRNTDNACM ETEAVNYHDE TGEIMDNLML
310 320 330 340 350
EAGDDAGKVK WVDINDKLKL YASHSQFIKL VAEKRDAHWS EDSEADCHAL
Length:350
Mass (Da):39,042
Last modified:December 1, 2001 - v1
Checksum:i8BE1A31ECCFB343D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK027295 mRNA. Translation: BAB55021.1.
RefSeqiNP_001234940.1. NM_001248011.1.
NP_076952.1. NM_024047.4.
UniGeneiHs.149500.

Genome annotation databases

GeneIDi53343.
KEGGihsa:53343.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ96KB3_HUMAN
AccessioniPrimary (citable) accession number: Q96KB3
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: July 5, 2017
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.