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Q96K80 (ZC3HA_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Zinc finger CCCH domain-containing protein 10
Gene names
Name:ZC3H10
Synonyms:ZC3HDC10
OrganismHomo sapiens (Human)
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Contains 3 C3H1-type zinc fingers.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

ATXN1P542533EBI-742550,EBI-930964

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 434434Zinc finger CCCH domain-containing protein 10
PRO_0000281145

Regions

Zinc finger36 – 6328C3H1-type 1
Zinc finger73 – 9927C3H1-type 2
Zinc finger134 – 16128C3H1-type 3
Coiled coil234 – 28047 Potential
Compositional bias10 – 3526Gly-rich
Compositional bias169 – 1768Poly-Gly
Compositional bias323 – 39674Pro-rich

Amino acid modifications

Modified residue1261Phosphoserine Ref.3

Sequences

Sequence LengthMass (Da)Tools
Q96K80 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: E4B24A526F3A573B

FASTA43446,052
        10         20         30         40         50         60 
MPDRDSYANG TGSSGGGPGG GGSEEASGAG VGSGGASSDA ICRDFLRNVC KRGKRCRYRH 

        70         80         90        100        110        120 
PDMSEVSNLG VSKNEFIFCH DFQNKECSRP NCRFIHGSKE DEDGYKKTGE LPPRLRQKVA 

       130        140        150        160        170        180 
AGLGLSPADL PNGKEEVPIC RDFLKGDCQR GAKCKFRHLQ RDFEFDARGG GGTGGGSTGS 

       190        200        210        220        230        240 
VLPGRRHDLY DIYDLPDRGF EDHEPGPKRR RGGCCPPDGP HFESYEYSLA PPRGVECRLL 

       250        260        270        280        290        300 
EEENAMLRKR VEELKKQVSN LLATNEVLLE QNAQFRNQAK VITLSSTAPA TEQTLAPTVG 

       310        320        330        340        350        360 
TVATFNHGIA QTHTTLSSQA LQPRPVSQQE LVAPAGAPAA PPTNAAPPAA PPPPPPHLTP 

       370        380        390        400        410        420 
EITPLSAALA QTIAQGMAPP PVSMAPVAVS VAPVAPVAVS MAQPLAGITM SHTTTPMVTY 

       430 
PIASQSMRIT AMPH

« Hide

References

[1]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Muscle.
[3]"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
Anal. Chem. 81:4493-4501(2009) [PubMed: 19413330] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-126, MASS SPECTROMETRY.
Tissue: Embryonic kidney.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AK027357 mRNA. Translation: BAB55059.1.
BC018708 mRNA. Translation: AAH18708.1.
IPIIPI00064474.
RefSeqNP_116175.1. NM_032786.1.
UniGeneHs.632706.

3D structure databases

ProteinModelPortalQ96K80.
SMRQ96K80. Positions 39-163.
ModBaseSearch...

Protein-protein interaction databases

IntActQ96K80. 5 interactions.
MINTMINT-1446979.
STRINGQ96K80.

Polymorphism databases

DMDM74760908.

Proteomic databases

PRIDEQ96K80.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000257940; ENSP00000257940; ENSG00000135482.
GeneID84872.
KEGGhsa:84872.
UCSCuc001sjp.1. human.

Organism-specific databases

CTD84872.
GeneCardsGC12P056512.
HGNCHGNC:25893. ZC3H10.
HPAHPA039236.
neXtProtNX_Q96K80.
PharmGKBPA142670534.
GenAtlasSearch...

Phylogenomic databases

eggNOGprNOG19671.
GeneTreeENSGT00390000005669.
HOGENOMHBG315696.
HOVERGENHBG060393.
InParanoidQ96K80.
OMAMPDRDSY.
OrthoDBEOG4V1716.
PhylomeDBQ96K80.

Gene expression databases

ArrayExpressQ96K80.
BgeeQ96K80.
CleanExHS_ZC3H10.
GenevestigatorQ96K80.

Family and domain databases

InterProIPR000571. Znf_CCCH.
[Graphical view]
PfamPF00642. zf-CCCH. 1 hit.
[Graphical view]
SMARTSM00356. ZnF_C3H1. 3 hits.
[Graphical view]
PROSITEPS50103. ZF_C3H1. 3 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio75163.

Entry information

Entry nameZC3HA_HUMAN
AccessionPrimary (citable) accession number: Q96K80
Entry history
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: December 1, 2001
Last modified: January 25, 2012
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 12

Human chromosome 12: entries, gene names and cross-references to MIM

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents