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Protein
Submitted name:

HSPA8 protein

Gene

HSPA8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
HSPA8 proteinImported
Gene namesi
Name:HSPA8Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiQ96IS6.
PeptideAtlasiQ96IS6.
PRIDEiQ96IS6.

Expressioni

Gene expression databases

BgeeiENSG00000109971.

Interactioni

Protein-protein interaction databases

IntActiQ96IS6. 5 interactors.
MINTiMINT-4933849.
STRINGi9606.ENSP00000227378.

Structurei

3D structure databases

ProteinModelPortaliQ96IS6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili453 – 476Sequence analysisAdd BLAST24

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0101. Eukaryota.
COG0443. LUCA.
HOVERGENiHBG051845.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
InterProiIPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
PROSITEiPS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q96IS6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
AMNPTNTVFD AKRLIGRRFD DAVVQSDMKH WPFMVVNDAG RPKVQVEYKG
60 70 80 90 100
ETKSFYPEEV SSMVLTKMKE IAEAYLGKTV TNAVVTVPAY FNDSQRQATK
110 120 130 140 150
DAGTIAGLNV LRIINEPTAA AIAYGLDKKV GAERNVLIFD LGGGTFDVSI
160 170 180 190 200
LTIEDGIFEV KSTAGDTHLG GEDFDNRMVN HFIAEFKRKH KKDISENKRA
210 220 230 240 250
VRRLRTACER AKRTLSSSTQ ASIEIDSLYE GIDFYTSITR ARFEELNADL
260 270 280 290 300
FRGTLDPVEK ALRDAKLDKS QIHDIVLVGG STRIPKIQKL LQDFFNGKEL
310 320 330 340 350
NKSINPDEAV AYGAAVQAAI LSGDKSENVQ DLLLLDVTPL SLGIETAGGV
360 370 380 390 400
MTVLIKRNTT IPTKQTQTFT TYSDNQPGVL IQVYEGERAM TKDNNLLGKF
410 420 430 440 450
ELTGIPPAPR GVPQIEVTFD IDANGILNVS AVDKSTGKEN KITITNDKGR
460 470 480 490 500
LSKEDIERMV QEAEKYKAED EKQRDKVSSK NSLESYAFNM KATVEDEKLQ
510 520 530 540 550
GKINDEDKQK ILDKCNEIIN WLDKNQTAEK EEFEHQQKEL EKVCNPIITK
560 570 580
LYQSAGGMPG GMPGGFPGGG APPSGGASSG PTIEEVD
Length:587
Mass (Da):64,673
Last modified:March 29, 2005 - v2
Checksum:iB215DB666384A7DC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC007276 mRNA. Translation: AAH07276.2.
UniGeneiHs.180414.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC007276 mRNA. Translation: AAH07276.2.
UniGeneiHs.180414.

3D structure databases

ProteinModelPortaliQ96IS6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ96IS6. 5 interactors.
MINTiMINT-4933849.
STRINGi9606.ENSP00000227378.

Proteomic databases

PaxDbiQ96IS6.
PeptideAtlasiQ96IS6.
PRIDEiQ96IS6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0101. Eukaryota.
COG0443. LUCA.
HOVERGENiHBG051845.

Miscellaneous databases

ChiTaRSiHSPA8. human.

Gene expression databases

BgeeiENSG00000109971.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
InterProiIPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
PROSITEiPS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ96IS6_HUMAN
AccessioniPrimary (citable) accession number: Q96IS6
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: March 29, 2005
Last modified: November 2, 2016
This is version 94 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.