Q96IH1 (Q96IH1_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Fascin PIRNR PIRNR005682

Gene names

Name:

FSCN1 EMBL AAH07539.1

Organism

Homo sapiens (Human) EMBL AAH07539.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	500 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Cytoplasm › cytoskeleton By similarity PIRNR PIRNR005682.
Sequence similarities	Belongs to the fascin family. PIRNR PIRNR005682

Ontologies

Keywords
Cellular component	Cytoplasm Cytoskeleton PIRNR PIRNR005682
Ligand	Actin-binding PIRNR PIRNR005682
Gene Ontology (GO)
Biological_process	actin filament bundle assembly Inferred from electronic annotation. Source: Compara cell migration Inferred from electronic annotation. Source: Compara
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW cytoskeleton Inferred from electronic annotation. Source: UniProtKB-SubCell filopodium Inferred from electronic annotation. Source: Compara
Molecular_function	drug binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAH07539.1

Sequences

	Sequence		Length	Mass (Da)
	Q96IH1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 80B06895E8A6DD74	FASTA	500	55,136
	10 20 30 40 50 60 SASSTATMTA NGTAEAVQIQ FGLINCGNKY LTAEAFGFKV NASASSLKKK QIWTLEQPPD 70 80 90 100 110 120 EAGSAAVCLR SHLGRYLAAD KDGNVTCERE VPGPDCRFLI VAHDDGRWSL QSEAHRRYFG 130 140 150 160 170 180 GTEDRLSCFA QTVSPAEKWS VHIAMHPQVN IYSVTRKRYA HLSARPADEI AVDRDVPWGV 190 200 210 220 230 240 DSLITLAFQD QRYSVQTADH RFLRHDGRLV ARPEPATGYT LEFRSGKVAF RDCEGRYLAP 250 260 270 280 290 300 SGPSGTLKAG KATKVGKDEL FALEQSCAQV VLQAANERNV STRQGMDLSA NQDEETDQET 310 320 330 340 350 360 FQLEIDRDTK KCAFRTHTGK YWTLTATGGV QSTASSKNAS CYFDIEWRDR RITLRASNGK 370 380 390 400 410 420 FVTSKKNGQL AASVETAGDS ELFLMKLINR PIIVFRGEHG FIGCRKVTGT LDANRSSYDV 430 440 450 460 470 480 FQLEFNDGAY NIKDSTGKYW TVGSDSAVTS SGDTPVDFFF EFCDYNKVAI KVGGRYLKGD 490 500 HAGVLKASAE TVDPASLWEY

References

[1]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Muscle EMBL AAH07539.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC007539 mRNA. Translation: AAH07539.1.
IPI	IPI00163187.
UniGene	Hs.118400.
3D structure databases
HSSP	HSSP built from PDB template 1DFC based on UniProtKB Q16658.
ModBase	Search...
Protein-protein interaction databases
MINT	MINT-1375527.
STRING	Q96IH1.
Proteomic databases
PRIDE	Q96IH1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOGENOM	HOG000267034.
HOVERGEN	HBG000968.
Gene expression databases
ArrayExpress	Q96IH1.
Bgee	Q96IH1.
Family and domain databases
InterPro	IPR008999. Actin_cross-linking. IPR010431. Fascin. IPR022768. Fascin-domain. IPR024703. Fascin_metazoans. [Graphical view]
PANTHER	PTHR10551. PTHR10551. 1 hit.
Pfam	PF06268. Fascin. 4 hits. [Graphical view]
PIRSF	PIRSF005682. Fascin. 1 hit.
SUPFAM	SSF50405. Actin_crosslink. 4 hits.
ProtoNet	Search...
Other
ChiTaRS	FSCN1. human.

Entry information

Entry name

Q96IH1_HUMAN

Accession

Primary (citable) accession number: Q96IH1

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	May 1, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.