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Protein
Submitted name:

VCP protein

Gene

VCP

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
VCP proteinImported
Gene namesi
Name:VCPImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA37289.

PTM / Processingi

Proteomic databases

PaxDbiQ96IF9.
PeptideAtlasiQ96IF9.
PRIDEiQ96IF9.

Expressioni

Gene expression databases

BgeeiENSG00000165280.
GenevisibleiQ96IF9. HS.

Interactioni

Protein-protein interaction databases

IntActiQ96IF9. 1 interaction.
STRINGi9606.ENSP00000351777.

Structurei

3D structure databases

ProteinModelPortaliQ96IF9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini75 – 211137AAAInterPro annotationAdd
BLAST
Domaini348 – 487140AAAInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the AAA ATPase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0730. Eukaryota.
COG0464. LUCA.
HOVERGENiHBG108504.
KOiK13525.

Family and domain databases

Gene3Di3.10.330.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR005938. AAA_ATPase_CDC48.
IPR003959. ATPase_AAA_core.
IPR003960. ATPase_AAA_CS.
IPR029067. CDC48_domain_2-like.
IPR027417. P-loop_NTPase.
IPR015415. Vps4_C.
[Graphical view]
PfamiPF00004. AAA. 2 hits.
PF09336. Vps4_C. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF54585. SSF54585. 1 hit.
TIGRFAMsiTIGR01243. CDC48. 1 hit.
PROSITEiPS00674. AAA. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q96IF9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
FKVVETDPSP YCIVAPDTVI HCEGEPIKRE DEEESLNEVG YDDIGGCRKQ
60 70 80 90 100
LAQIKEMVEL PLRHPALFKA IGVKPPRGIL LYGPPGTGKT LIARAVANET
110 120 130 140 150
GAFFFLINGP EIMSKLAGES ESNLRKAFEE AEKNAPAIIF IDELDAIAPK
160 170 180 190 200
REKTHGEVER RIVSQLLTLM DGLKQRAHVI VMAATNRPNS IDPALRRFGR
210 220 230 240 250
FDREVDIGIP DATGRLEILQ IHTKNMKLAD DVDLEQVANE THGHVGADLA
260 270 280 290 300
ALCSEAALQA IRKKMDLIDL EDETIDAEVM NSLAVTMDDF RWALSQSNPS
310 320 330 340 350
ALRETVVEVP QVTWEDIGGL EDVKRELQEL VQYPVEHPDK FLKFGMTPSK
360 370 380 390 400
GVLFYGPPGC GKTLLAKAIA NECQANFISI KGPELLTMWF GESEANVREI
410 420 430 440 450
FDKARQAAPC VLFFDELDSI AKARGGNIGD GGGAADRVIN QILTEMDGMS
460 470 480 490 500
TKKNVFIIGA TNRPDIIDPA ILRPGRLDQL IYIPLPDEKS RVAILKANLR
510 520 530 540 550
KSPVAKDVDL EFLAKMTNGF SGADLTEICQ RACKLAIRES IESEIRRERE
560 570 580 590 600
RQTNPSAMEV EEDDPVPEIR RDHFEEAMRF ARRSVSDNDI RKYEMFAQTL
610 620 630 640
QQSRGFGSFR FPSGNQGGAG PSQGSGGGTG GSVYTEDNDD DLYG
Length:644
Mass (Da):71,066
Last modified:March 29, 2005 - v2
Checksum:i028EB4C879131578
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC007562 mRNA. Translation: AAH07562.2.
RefSeqiNP_009057.1. NM_007126.3.
UniGeneiHs.529782.

Genome annotation databases

GeneIDi7415.
KEGGihsa:7415.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC007562 mRNA. Translation: AAH07562.2.
RefSeqiNP_009057.1. NM_007126.3.
UniGeneiHs.529782.

3D structure databases

ProteinModelPortaliQ96IF9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ96IF9. 1 interaction.
STRINGi9606.ENSP00000351777.

Proteomic databases

PaxDbiQ96IF9.
PeptideAtlasiQ96IF9.
PRIDEiQ96IF9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7415.
KEGGihsa:7415.

Organism-specific databases

CTDi7415.
PharmGKBiPA37289.

Phylogenomic databases

eggNOGiKOG0730. Eukaryota.
COG0464. LUCA.
HOVERGENiHBG108504.
KOiK13525.

Miscellaneous databases

ChiTaRSiVCP. human.
GenomeRNAii7415.

Gene expression databases

BgeeiENSG00000165280.
GenevisibleiQ96IF9. HS.

Family and domain databases

Gene3Di3.10.330.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR005938. AAA_ATPase_CDC48.
IPR003959. ATPase_AAA_core.
IPR003960. ATPase_AAA_CS.
IPR029067. CDC48_domain_2-like.
IPR027417. P-loop_NTPase.
IPR015415. Vps4_C.
[Graphical view]
PfamiPF00004. AAA. 2 hits.
PF09336. Vps4_C. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF54585. SSF54585. 1 hit.
TIGRFAMsiTIGR01243. CDC48. 1 hit.
PROSITEiPS00674. AAA. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ96IF9_HUMAN
AccessioniPrimary (citable) accession number: Q96IF9
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: March 29, 2005
Last modified: September 7, 2016
This is version 89 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.