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Protein
Submitted name:

Homeobox-containing protein PKNOX1

Gene

PKNOX1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi259 – 321HomeoboxPROSITE-ProRule annotationAdd BLAST63

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotationImported

Names & Taxonomyi

Protein namesi
Submitted name:
Homeobox-containing protein PKNOX1Imported
Submitted name:
PBX/knotted 1 homeobox 1Imported
Submitted name:
PBX/knotted 1 homeobox 1, isoform CRA_bImported
Gene namesi
Name:PKNOX1Imported
ORF Names:hCG_2043122Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000160199.14.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA33354.

PTM / Processingi

Proteomic databases

MaxQBiQ96I87.

Expressioni

Gene expression databases

BgeeiENSG00000160199.
ExpressionAtlasiQ96I87. baseline and differential.

Interactioni

Binary interactionsi

Show more details

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ96I87. 2 interactors.

Structurei

3D structure databases

SMRiQ96I87.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini257 – 320HomeoboxInterPro annotationAdd BLAST64

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotationImported

Phylogenomic databases

eggNOGiKOG0773. Eukaryota.
ENOG410XPMQ. LUCA.
HOVERGENiHBG055193.
OMAiMMAEQSE.
OrthoDBiEOG091G09WJ.

Family and domain databases

CDDicd00086. homeodomain. 1 hit.
InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR001356. Homeobox_dom.
IPR008422. Homeobox_KN_domain.
IPR032453. PKNOX/Meis_N.
PfamiView protein in Pfam
PF05920. Homeobox_KN. 1 hit.
PF16493. Meis_PKNOX_N. 1 hit.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS50071. HOMEOBOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q96I87-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMATQTLSID SYQDGQQMQV VTELKTEQDP NCSEPDAEGV SPPPVESQTP
60 70 80 90 100
MDVDKQAIYR HPLFPLLALL FEKCEQSTQG SEGTTSASFD VDIENFVRKQ
110 120 130 140 150
EKEGKPFFCE DPETDNLMVK AIQVLRIHLL ELEKVNELCK DFCSRYIACL
160 170 180 190 200
KTKMNSETLL SGEPGSPYSP VQSQQIQSAI TGTISPQGIV VPASALQQGN
210 220 230 240 250
VAMATVAGGT VYQPVTVVTP QGQVVTQTLS PGTIRIQNSQ LQLQLNQDLS
260 270 280 290 300
ILHQDDGSSK NKRGVLPKHA TNVMRSWLFQ HIGHPYPTED EKKQIAAQTN
310 320 330 340 350
LTLLQVNNWF INARRRILQP MLDSSCSETP KTKKKTAQNR PVQRFWPDSI
360 370 380 390 400
ASGVAQPPPS ELTMSEGAVV TITTPVNMNV DSLQSLSSDG ATLAVQQVMM
410 420 430
AGQSEDESVD STEEDAGALA PAHISGLVLE NSDSLQ
Length:436
Mass (Da):47,607
Last modified:December 1, 2001 - v1
Checksum:i381E901F435AC5F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC007746 mRNA. Translation: AAH07746.1.
AY196965 mRNA. Translation: AAO45825.1.
CH471079 Genomic DNA. Translation: EAX09518.1.
RefSeqiNP_001273187.1. NM_001286258.1.
NP_001307623.1. NM_001320694.1.
NP_004562.2. NM_004571.4.
UniGeneiHs.431043.

Genome annotation databases

GeneIDi5316.
KEGGihsa:5316.
UCSCiuc002zcq.3. human.

Similar proteinsi

Entry informationi

Entry nameiQ96I87_HUMAN
AccessioniPrimary (citable) accession number: Q96I87
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: September 27, 2017
This is version 140 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.