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Protein

MORF4 family-associated protein 1-like 1

Gene

MRFAP1L1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • identical protein binding Source: IntAct

Names & Taxonomyi

Protein namesi
Recommended name:
MORF4 family-associated protein 1-like 1
Gene namesi
ORF Names:PP784
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiHostDB:ENSG00000178988.10.
HGNCiHGNC:28796. MRFAP1L1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000178988.
PharmGKBiPA142671333.

Polymorphism and mutation databases

BioMutaiMRFAP1L1.
DMDMi74731978.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003187181 – 127MORF4 family-associated protein 1-like 1Add BLAST127

Proteomic databases

EPDiQ96HT8.
MaxQBiQ96HT8.
PaxDbiQ96HT8.
PeptideAtlasiQ96HT8.
PRIDEiQ96HT8.

PTM databases

iPTMnetiQ96HT8.
PhosphoSitePlusiQ96HT8.

Expressioni

Gene expression databases

BgeeiENSG00000178988.
CleanExiHS_MRFAP1L1.
ExpressionAtlasiQ96HT8. baseline and differential.
GenevisibleiQ96HT8. HS.

Interactioni

Binary interactionsi

Show more details

GO - Molecular functioni

  • identical protein binding Source: IntAct

Protein-protein interaction databases

BioGridi125400. 38 interactors.
DIPiDIP-29019N.
IntActiQ96HT8. 48 interactors.
MINTiMINT-1472696.
STRINGi9606.ENSP00000318154.

Structurei

3D structure databases

ProteinModelPortaliQ96HT8.
SMRiQ96HT8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili87 – 118Sequence analysisAdd BLAST32

Sequence similaritiesi

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410JCRB. Eukaryota.
ENOG41114ZF. LUCA.
GeneTreeiENSGT00510000048749.
HOGENOMiHOG000070216.
HOVERGENiHBG104090.
InParanoidiQ96HT8.
OMAiVWRIEKS.
OrthoDBiEOG091G10XY.
PhylomeDBiQ96HT8.
TreeFamiTF338232.

Family and domain databases

InterProiView protein in InterPro
IPR029254. MRFAP1.
PANTHERiPTHR31324. PTHR31324. 1 hit.
PfamiView protein in Pfam
PF15155. MRFAP1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q96HT8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPLDIDEVE APEEVEVLEP EEDFEQFLLP VINEMREDIA SLIREHGRAY
60 70 80 90 100
LRTRSKLWEM DNMLIQIKTQ VEASEESALN HVQHPSGEAD ERVSELCEKA
110 120
EEKAKEIAKM AEMLVELVWR IERSESS
Length:127
Mass (Da):14,808
Last modified:December 1, 2001 - v1
Checksum:i6C914B0B4BEECAE5
GO

Sequence cautioni

The sequence AAF67011 differs from that shown. Reason: Frameshift at position 89.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti33N → H in AAH66897 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF155654 mRNA. Translation: AAF67011.1. Frameshift.
AF258591 mRNA. Translation: AAG23794.1.
AK312676 mRNA. Translation: BAG35557.1.
CH471131 Genomic DNA. Translation: EAW82383.1.
BC008087 mRNA. Translation: AAH08087.1.
BC066897 mRNA. Translation: AAH66897.1.
CCDSiCCDS3392.1.
RefSeqiNP_982287.1. NM_203462.2.
XP_005247989.1. XM_005247932.1.
UniGeneiHs.593159.

Genome annotation databases

EnsembliENST00000320848; ENSP00000318154; ENSG00000178988.
GeneIDi114932.
KEGGihsa:114932.
UCSCiuc003gjo.5. human.

Similar proteinsi

Entry informationi

Entry nameiMR1L1_HUMAN
AccessioniPrimary (citable) accession number: Q96HT8
Secondary accession number(s): B2R6R0, Q6NXT8, Q9P0J5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: December 1, 2001
Last modified: November 22, 2017
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families