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Protein

MORF4 family-associated protein 1-like 1

Gene

MRFAP1L1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • identical protein binding Source: IntAct

Names & Taxonomyi

Protein namesi
Recommended name:
MORF4 family-associated protein 1-like 1
Gene namesi
ORF Names:PP784
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi

Organism-specific databases

EuPathDBiHostDB:ENSG00000178988.10
HGNCiHGNC:28796 MRFAP1L1
neXtProtiNX_Q96HT8

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000178988
PharmGKBiPA142671333

Polymorphism and mutation databases

BioMutaiMRFAP1L1
DMDMi74731978

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003187181 – 127MORF4 family-associated protein 1-like 1Add BLAST127

Proteomic databases

EPDiQ96HT8
MaxQBiQ96HT8
PaxDbiQ96HT8
PeptideAtlasiQ96HT8
PRIDEiQ96HT8

PTM databases

iPTMnetiQ96HT8
PhosphoSitePlusiQ96HT8

Expressioni

Gene expression databases

BgeeiENSG00000178988
CleanExiHS_MRFAP1L1
ExpressionAtlasiQ96HT8 baseline and differential
GenevisibleiQ96HT8 HS

Interactioni

Binary interactionsi

Show more details

GO - Molecular functioni

  • identical protein binding Source: IntAct

Protein-protein interaction databases

BioGridi125400, 38 interactors
DIPiDIP-29019N
IntActiQ96HT8, 47 interactors
MINTiQ96HT8
STRINGi9606.ENSP00000318154

Structurei

3D structure databases

ProteinModelPortaliQ96HT8
SMRiQ96HT8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili87 – 118Sequence analysisAdd BLAST32

Sequence similaritiesi

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410JCRB Eukaryota
ENOG41114ZF LUCA
GeneTreeiENSGT00510000048749
HOGENOMiHOG000070216
HOVERGENiHBG104090
InParanoidiQ96HT8
OMAiVWRIEKS
OrthoDBiEOG091G10XY
PhylomeDBiQ96HT8
TreeFamiTF338232

Family and domain databases

InterProiView protein in InterPro
IPR029254 MRFAP1
PANTHERiPTHR31324 PTHR31324, 1 hit
PfamiView protein in Pfam
PF15155 MRFAP1, 1 hit

Sequencei

Sequence statusi: Complete.

Q96HT8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPLDIDEVE APEEVEVLEP EEDFEQFLLP VINEMREDIA SLIREHGRAY
60 70 80 90 100
LRTRSKLWEM DNMLIQIKTQ VEASEESALN HVQHPSGEAD ERVSELCEKA
110 120
EEKAKEIAKM AEMLVELVWR IERSESS
Length:127
Mass (Da):14,808
Last modified:December 1, 2001 - v1
Checksum:i6C914B0B4BEECAE5
GO

Sequence cautioni

The sequence AAF67011 differs from that shown. Reason: Frameshift at position 89.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti33N → H in AAH66897 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF155654 mRNA Translation: AAF67011.1 Frameshift.
AF258591 mRNA Translation: AAG23794.1
AK312676 mRNA Translation: BAG35557.1
CH471131 Genomic DNA Translation: EAW82383.1
BC008087 mRNA Translation: AAH08087.1
BC066897 mRNA Translation: AAH66897.1
CCDSiCCDS3392.1
RefSeqiNP_982287.1, NM_203462.2
XP_005247989.1, XM_005247932.1
UniGeneiHs.593159

Genome annotation databases

EnsembliENST00000320848; ENSP00000318154; ENSG00000178988
GeneIDi114932
KEGGihsa:114932
UCSCiuc003gjo.5 human

Similar proteinsi

Entry informationi

Entry nameiMR1L1_HUMAN
AccessioniPrimary (citable) accession number: Q96HT8
Secondary accession number(s): B2R6R0, Q6NXT8, Q9P0J5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: December 1, 2001
Last modified: May 23, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

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