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Protein

UPF0562 protein C7orf55

Gene

C7orf55

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0562 protein C7orf55
Gene namesi
Name:C7orf55
ORF Names:HSPC268
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

HGNCiHGNC:26946. C7orf55.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA164717374.

Polymorphism and mutation databases

DMDMi182627648.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 113113UPF0562 protein C7orf55PRO_0000328780Add
BLAST

Proteomic databases

EPDiQ96HJ9.
MaxQBiQ96HJ9.
PaxDbiQ96HJ9.
PeptideAtlasiQ96HJ9.
PRIDEiQ96HJ9.

PTM databases

iPTMnetiQ96HJ9.
PhosphoSiteiQ96HJ9.

Expressioni

Gene expression databases

BgeeiENSG00000164898.
GenevisibleiQ96HJ9. HS.

Organism-specific databases

HPAiHPA045663.
HPA050553.
HPA051631.

Interactioni

Protein-protein interaction databases

BioGridi127556. 10 interactions.
STRINGi9606.ENSP00000297534.

Structurei

3D structure databases

ProteinModelPortaliQ96HJ9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0562 family.Curated

Phylogenomic databases

eggNOGiENOG410J415. Eukaryota.
ENOG4111SA8. LUCA.
GeneTreeiENSGT00390000012258.
ENSGT00730000110670.
HOGENOMiHOG000215956.
HOVERGENiHBG106720.
InParanoidiQ96HJ9.
KOiK13212.
OMAiPAHTFRG.
OrthoDBiEOG091G11LV.
PhylomeDBiQ96HJ9.
TreeFamiTF321497.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q96HJ9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAALGSPSHT FRGLLRELRY LSAATGRPYR DTAAYRYLVK AFRAHRVTSE
60 70 80 90 100
KLCRAQHELH FQAATYLCLL RSIRKHVALH QEFHGKGERS VEESAGLVGL
110
KLPHQPGGKG WEP
Length:113
Mass (Da):12,749
Last modified:April 8, 2008 - v2
Checksum:i98233A93133877C9
GO
Isoform 2 (identifier: Q96HJ9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     88-113: ERSVEESAGLVGLKLPHQPGGKGWEP → DTTRQRIKFS...SSEEREAGEI

Note: No experimental confirmation available.
Show »
Length:458
Mass (Da):54,224
Checksum:i79850BF28BEF3C13
GO

Sequence cautioni

The sequence AAF28946 differs from that shown. Reason: Frameshift at position 64. Curated
The sequence AAF28946 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti8 – 81S → A.1 Publication
Corresponds to variant rs10265 [ dbSNP | Ensembl ].
VAR_042520

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei88 – 11326ERSVE…KGWEP → DTTRQRIKFSDDRVCKSHLL NCCPHDVLSGTRMDLGECLK VHDLALRADYEIASKEQDFF FELDAMDHLQSFIADCDRRT EVAKKRLAETQEEISAEVAA KAERVHELNEEIGKLLAKVE QLGAEGNVEESQKVMDEVEK ARAKKREAEEVYRNSMPASS FQQQKLRVCEVCSAYLGLHD NDRRLADHFGGKLHLGFIEI REKLEELKRVVAEKQEKRNQ ERLKRREEREREEREKLRRS RSHSKNPKRSRSREHRRHRS RSMSRERKRRTRSKSREKRH RHRSRSSSRSRSRSHQRSRH SSRDRSRERSKRRSSKERFR DQDLASCDRDRSSRDRSPRD RDRKDKKRSYESANGRSEDR RSSEEREAGEI in isoform 2. 1 PublicationVSP_047244Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK297642 mRNA. Translation: BAH12639.1.
AF161386 mRNA. Translation: AAF28946.1. Sequence problems.
AC083880 Genomic DNA. Translation: AAS07478.1.
AC083883 Genomic DNA. No translation available.
CH471070 Genomic DNA. Translation: EAW83915.1.
BC008467 mRNA. Translation: AAH08467.1.
CCDSiCCDS5853.1. [Q96HJ9-1]
RefSeqiNP_001231513.1. NM_001244584.2. [Q96HJ9-2]
NP_932068.2. NM_197964.4. [Q96HJ9-1]
UniGeneiHs.718441.
Hs.731488.

Genome annotation databases

EnsembliENST00000297534; ENSP00000297534; ENSG00000164898. [Q96HJ9-1]
GeneIDi100996928.
154791.
KEGGihsa:100996928.
hsa:154791.
UCSCiuc003vuw.5. human. [Q96HJ9-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK297642 mRNA. Translation: BAH12639.1.
AF161386 mRNA. Translation: AAF28946.1. Sequence problems.
AC083880 Genomic DNA. Translation: AAS07478.1.
AC083883 Genomic DNA. No translation available.
CH471070 Genomic DNA. Translation: EAW83915.1.
BC008467 mRNA. Translation: AAH08467.1.
CCDSiCCDS5853.1. [Q96HJ9-1]
RefSeqiNP_001231513.1. NM_001244584.2. [Q96HJ9-2]
NP_932068.2. NM_197964.4. [Q96HJ9-1]
UniGeneiHs.718441.
Hs.731488.

3D structure databases

ProteinModelPortaliQ96HJ9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi127556. 10 interactions.
STRINGi9606.ENSP00000297534.

PTM databases

iPTMnetiQ96HJ9.
PhosphoSiteiQ96HJ9.

Polymorphism and mutation databases

DMDMi182627648.

Proteomic databases

EPDiQ96HJ9.
MaxQBiQ96HJ9.
PaxDbiQ96HJ9.
PeptideAtlasiQ96HJ9.
PRIDEiQ96HJ9.

Protocols and materials databases

DNASUi154791.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000297534; ENSP00000297534; ENSG00000164898. [Q96HJ9-1]
GeneIDi100996928.
154791.
KEGGihsa:100996928.
hsa:154791.
UCSCiuc003vuw.5. human. [Q96HJ9-1]

Organism-specific databases

CTDi100996928.
154791.
GeneCardsiC7orf55.
HGNCiHGNC:26946. C7orf55.
HPAiHPA045663.
HPA050553.
HPA051631.
neXtProtiNX_Q96HJ9.
PharmGKBiPA164717374.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410J415. Eukaryota.
ENOG4111SA8. LUCA.
GeneTreeiENSGT00390000012258.
ENSGT00730000110670.
HOGENOMiHOG000215956.
HOVERGENiHBG106720.
InParanoidiQ96HJ9.
KOiK13212.
OMAiPAHTFRG.
OrthoDBiEOG091G11LV.
PhylomeDBiQ96HJ9.
TreeFamiTF321497.

Miscellaneous databases

PROiQ96HJ9.

Gene expression databases

BgeeiENSG00000164898.
GenevisibleiQ96HJ9. HS.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiCG055_HUMAN
AccessioniPrimary (citable) accession number: Q96HJ9
Secondary accession number(s): B7Z4Q3, Q75M90, Q9P0B3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: April 8, 2008
Last modified: September 7, 2016
This is version 101 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families
  5. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.