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Protein

Uncharacterized protein C16orf74

Gene

C16orf74

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C16orf74
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

HGNCiHGNC:23362. C16orf74.

Pathology & Biotechi

Polymorphism and mutation databases

BioMutaiC16orf74.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7676Uncharacterized protein C16orf74PRO_0000264621Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei44 – 441PhosphothreonineCombined sources
Modified residuei46 – 461PhosphothreonineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ96GX8.
PaxDbiQ96GX8.
PeptideAtlasiQ96GX8.
PRIDEiQ96GX8.

PTM databases

iPTMnetiQ96GX8.
PhosphoSiteiQ96GX8.

Expressioni

Gene expression databases

BgeeiQ96GX8.
CleanExiHS_C16orf74.
ExpressionAtlasiQ96GX8. baseline and differential.
GenevisibleiQ96GX8. HS.

Organism-specific databases

HPAiHPA049367.

Interactioni

Protein-protein interaction databases

BioGridi135663. 2 interactions.
IntActiQ96GX8. 2 interactions.
MINTiMINT-1456677.
STRINGi9606.ENSP00000284245.

Structurei

3D structure databases

ProteinModelPortaliQ96GX8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410J40B. Eukaryota.
ENOG41118KG. LUCA.
GeneTreeiENSGT00390000015933.
HOGENOMiHOG000111902.
HOVERGENiHBG081317.
InParanoidiQ96GX8.
OMAiKMCGSSS.
OrthoDBiEOG7JT706.
PhylomeDBiQ96GX8.
TreeFamiTF338382.

Family and domain databases

InterProiIPR027864. DUF4597.
[Graphical view]
PfamiPF15366. DUF4597. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q96GX8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLKMSCLKG FQMCVSSSSS SHDEAPVLND KHLDVPDIII TPPTPTGMML
60 70
PRDLGSTVWL DETGSCPDDG EIDPEA
Length:76
Mass (Da):8,118
Last modified:April 5, 2011 - v2
Checksum:i525DD517D5EA9F12
GO

Sequence cautioni

The sequence BC009078 differs from that shown.Intron retention.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018695 Genomic DNA. No translation available.
BC009078 mRNA. No translation available.
BQ672221 mRNA. No translation available.
CCDSiCCDS45540.1.
RefSeqiNP_996850.1. NM_206967.2.
XP_006721254.2. XM_006721191.2.
UniGeneiHs.461655.

Genome annotation databases

EnsembliENST00000284245; ENSP00000284245; ENSG00000154102.
GeneIDi404550.
KEGGihsa:404550.
UCSCiuc002fjc.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018695 Genomic DNA. No translation available.
BC009078 mRNA. No translation available.
BQ672221 mRNA. No translation available.
CCDSiCCDS45540.1.
RefSeqiNP_996850.1. NM_206967.2.
XP_006721254.2. XM_006721191.2.
UniGeneiHs.461655.

3D structure databases

ProteinModelPortaliQ96GX8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi135663. 2 interactions.
IntActiQ96GX8. 2 interactions.
MINTiMINT-1456677.
STRINGi9606.ENSP00000284245.

PTM databases

iPTMnetiQ96GX8.
PhosphoSiteiQ96GX8.

Polymorphism and mutation databases

BioMutaiC16orf74.

Proteomic databases

MaxQBiQ96GX8.
PaxDbiQ96GX8.
PeptideAtlasiQ96GX8.
PRIDEiQ96GX8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000284245; ENSP00000284245; ENSG00000154102.
GeneIDi404550.
KEGGihsa:404550.
UCSCiuc002fjc.5. human.

Organism-specific databases

CTDi404550.
GeneCardsiC16orf74.
H-InvDBHIX0202300.
HGNCiHGNC:23362. C16orf74.
HPAiHPA049367.
neXtProtiNX_Q96GX8.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410J40B. Eukaryota.
ENOG41118KG. LUCA.
GeneTreeiENSGT00390000015933.
HOGENOMiHOG000111902.
HOVERGENiHBG081317.
InParanoidiQ96GX8.
OMAiKMCGSSS.
OrthoDBiEOG7JT706.
PhylomeDBiQ96GX8.
TreeFamiTF338382.

Miscellaneous databases

ChiTaRSiC16orf74. human.
GenomeRNAii404550.
PROiQ96GX8.

Gene expression databases

BgeeiQ96GX8.
CleanExiHS_C16orf74.
ExpressionAtlasiQ96GX8. baseline and differential.
GenevisibleiQ96GX8. HS.

Family and domain databases

InterProiIPR027864. DUF4597.
[Graphical view]
PfamiPF15366. DUF4597. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The sequence and analysis of duplication-rich human chromosome 16."
    Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.
    , Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J., Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D., Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M., Rubin E.M., Pennacchio L.A.
    Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Colon.
  3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-44 AND THR-46, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  4. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.

Entry informationi

Entry nameiCP074_HUMAN
AccessioniPrimary (citable) accession number: Q96GX8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: April 5, 2011
Last modified: July 6, 2016
This is version 83 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.