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Protein

Putative ataxin-7-like protein 3B

Gene

ATXN7L3B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Putative ataxin-7-like protein 3B
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 12

Organism-specific databases

HGNCiHGNC:37931. ATXN7L3B.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA165512339.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 9797Putative ataxin-7-like protein 3BPRO_0000392529Add
BLAST

Proteomic databases

MaxQBiQ96GX2.
PRIDEiQ96GX2.

PTM databases

PhosphoSiteiQ96GX2.

Expressioni

Gene expression databases

BgeeiQ96GX2.
GenevisibleiQ96GX2. HS.

Interactioni

Protein-protein interaction databases

BioGridi139266. 2 interactions.
IntActiQ96GX2. 1 interaction.
STRINGi9606.ENSP00000430000.

Structurei

3D structure databases

ProteinModelPortaliQ96GX2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SGF11 family.Curated

Phylogenomic databases

GeneTreeiENSGT00390000012202.
InParanoidiQ96GX2.
OMAiVEEKGAC.
OrthoDBiEOG7BZVTK.
PhylomeDBiQ96GX2.
TreeFamiTF353123.

Sequencei

Sequence statusi: Complete.

Q96GX2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEISLANLD TNKLEAIAQE IYVDLIEDSC LGFCFEVHRA VKCGYFYLEF
60 70 80 90
AETGSVKDFG IQPVEDKGAC RLPLCSLPGE PGNGPDQQLQ RSPPEFQ
Length:97
Mass (Da):10,771
Last modified:March 23, 2010 - v2
Checksum:i722ADB410FCEFC9A
GO

Sequence cautioni

The sequence AAH09111.1 differs from that shown. Reason: Erroneous translation. Wrong choice of CDS.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025257 Genomic DNA. No translation available.
BC009111 mRNA. Translation: AAH09111.1. Sequence problems.
CCDSiCCDS53815.1.
RefSeqiNP_001129734.1. NM_001136262.1.
UniGeneiHs.744849.

Genome annotation databases

EnsembliENST00000519948; ENSP00000430000; ENSG00000253719.
GeneIDi552889.
KEGGihsa:552889.
UCSCiuc001sxd.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025257 Genomic DNA. No translation available.
BC009111 mRNA. Translation: AAH09111.1. Sequence problems.
CCDSiCCDS53815.1.
RefSeqiNP_001129734.1. NM_001136262.1.
UniGeneiHs.744849.

3D structure databases

ProteinModelPortaliQ96GX2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi139266. 2 interactions.
IntActiQ96GX2. 1 interaction.
STRINGi9606.ENSP00000430000.

PTM databases

PhosphoSiteiQ96GX2.

Proteomic databases

MaxQBiQ96GX2.
PRIDEiQ96GX2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000519948; ENSP00000430000; ENSG00000253719.
GeneIDi552889.
KEGGihsa:552889.
UCSCiuc001sxd.4. human.

Organism-specific databases

CTDi552889.
GeneCardsiGC12P074931.
HGNCiHGNC:37931. ATXN7L3B.
MIMi615579. gene.
neXtProtiNX_Q96GX2.
PharmGKBiPA165512339.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00390000012202.
InParanoidiQ96GX2.
OMAiVEEKGAC.
OrthoDBiEOG7BZVTK.
PhylomeDBiQ96GX2.
TreeFamiTF353123.

Miscellaneous databases

ChiTaRSiATXN7L3B. human.
GenomeRNAii552889.
NextBioi112362.
PROiQ96GX2.
SOURCEiSearch...

Gene expression databases

BgeeiQ96GX2.
GenevisibleiQ96GX2. HS.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The finished DNA sequence of human chromosome 12."
    Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
    , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A.
    Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Cervix.
  3. "Genome-wide survey for biologically functional pseudogenes."
    Svensson O., Arvestad L., Lagergren J.
    PLoS Comput. Biol. 2:E46-E46(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiA7L3B_HUMAN
AccessioniPrimary (citable) accession number: Q96GX2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 23, 2010
Last sequence update: March 23, 2010
Last modified: July 22, 2015
This is version 67 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Miscellaneous

Encoded by an expressed retrotransposed copy of the ATXN7L3 locus that emerged prior to the speciation event separating primates and rodents.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.