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Protein

X antigen family member 2

Gene

XAGE2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
X antigen family member 2
Short name:
XAGE-2
Alternative name(s):
Cancer/testis antigen 12.2
Short name:
CT12.2
G antigen family D member 3
Gene namesi
Name:XAGE2
Synonyms:GAGED3, XAGE2B
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000155622.6
HGNCiHGNC:4112 XAGE2
MIMi300416 gene
neXtProtiNX_Q96GT9

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000155622
PharmGKBiPA28527

Polymorphism and mutation databases

DMDMi21759127

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001483501 – 111X antigen family member 2Add BLAST111

Proteomic databases

MaxQBiQ96GT9
PaxDbiQ96GT9
PeptideAtlasiQ96GT9
PRIDEiQ96GT9

PTM databases

iPTMnetiQ96GT9
PhosphoSitePlusiQ96GT9

Expressioni

Gene expression databases

BgeeiENSG00000155622
CleanExiHS_XAGE2
ExpressionAtlasiQ96GT9 baseline and differential
GenevisibleiQ96GT9 HS

Organism-specific databases

HPAiHPA052507
HPA060900

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi114881, 12 interactors
IntActiQ96GT9, 7 interactors
STRINGi9606.ENSP00000333775

Structurei

3D structure databases

ProteinModelPortaliQ96GT9
SMRiQ96GT9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GAGE family.Curated

Phylogenomic databases

eggNOGiENOG410JJIA Eukaryota
ENOG4111B57 LUCA
GeneTreeiENSGT00900000141201
HOGENOMiHOG000237345
HOVERGENiHBG056227
InParanoidiQ96GT9
OMAiGDECEDG
OrthoDBiEOG091G14WQ
PhylomeDBiQ96GT9
TreeFamiTF340669

Family and domain databases

InterProiView protein in InterPro
IPR031320 GAGE
IPR008625 GAGE_fam
PANTHERiPTHR14047 PTHR14047, 1 hit
PfamiView protein in Pfam
PF05831 GAGE, 1 hit
SMARTiView protein in SMART
SM01379 GAGE, 1 hit

Sequencei

Sequence statusi: Complete.

Q96GT9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSWRGRSTYR PRPRRSLQPP ELIGAMLEPT DEEPKEEKPP TKSRNPTPDQ
60 70 80 90 100
KREDDQGAAE IQVPDLEADL QELCQTKTGD GCEGGTDVKG KILPKAEHFK
110
MPEAGEGKSQ V
Length:111
Mass (Da):12,354
Last modified:December 1, 2001 - v1
Checksum:i38C93332C5BA0E14
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ318891, AJ318892 Genomic DNA Translation: CAC88125.1
AJ318880 mRNA Translation: CAC83007.1
BX293536 Genomic DNA No translation available.
AL953874 Genomic DNA Translation: CAI41681.1
BC009232 mRNA Translation: AAH09232.1
BC066311 mRNA Translation: AAH66311.1
CCDSiCCDS59525.1
RefSeqiNP_570133.1, NM_130777.2
XP_011529138.1, XM_011530836.2
UniGeneiHs.409726
Hs.522654

Genome annotation databases

EnsembliENST00000286049; ENSP00000286049; ENSG00000155622
GeneIDi9502
KEGGihsa:9502
UCSCiuc004dqe.4 human

Similar proteinsi

Entry informationi

Entry nameiXAGE2_HUMAN
AccessioniPrimary (citable) accession number: Q96GT9
Secondary accession number(s): Q5HYR4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: December 1, 2001
Last modified: May 23, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health