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Protein

Protein FAM163A

Gene

FAM163A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM163A
Alternative name(s):
Cebelin
Neuroblastoma-derived secretory protein
Gene namesi
Name:FAM163A
Synonyms:C1orf76, NDSP
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000143340.6.
HGNCiHGNC:28274. FAM163A.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 26HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

DisGeNETi148753.
OpenTargetsiENSG00000143340.
PharmGKBiPA162386944.

Polymorphism and mutation databases

BioMutaiFAM163A.
DMDMi74751887.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002802561 – 167Protein FAM163AAdd BLAST167

Proteomic databases

EPDiQ96GL9.
PaxDbiQ96GL9.
PRIDEiQ96GL9.
TopDownProteomicsiQ96GL9.

PTM databases

iPTMnetiQ96GL9.
PhosphoSitePlusiQ96GL9.

Expressioni

Tissue specificityi

Highly expressed in neuroblastoma compared to other tissues, suggesting that it may be used as a marker for metastasis in bone marrow.1 Publication

Gene expression databases

BgeeiENSG00000143340.
CleanExiHS_FAM163A.
GenevisibleiQ96GL9. HS.

Organism-specific databases

HPAiHPA010778.

Interactioni

Protein-protein interaction databases

BioGridi127166. 9 interactors.
IntActiQ96GL9. 1 interactor.
STRINGi9606.ENSP00000354891.

Structurei

3D structure databases

ProteinModelPortaliQ96GL9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM163 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IWXQ. Eukaryota.
ENOG41120YS. LUCA.
GeneTreeiENSGT00390000002397.
HOGENOMiHOG000013172.
HOVERGENiHBG100700.
InParanoidiQ96GL9.
OMAiSPFYIRT.
OrthoDBiEOG091G0QQ1.
PhylomeDBiQ96GL9.
TreeFamiTF333084.

Family and domain databases

InterProiView protein in InterPro
IPR029379. FAM163.
PfamiView protein in Pfam
PF15069. FAM163. 1 hit.

Sequencei

Sequence statusi: Complete.

Q96GL9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAGTVVITG GILATVILLC IIAVLCYCRL QYYCCKKSGT EVADEEEERE
60 70 80 90 100
HDLPTHPRGP TCNACSSQAL DGRGSLAPLT SEPCSQPCGV AASHCTTCSP
110 120 130 140 150
YSSPFYIRTA DMVPNGGGGE RLSFAPTYYK EGGPPSLKLA APQSYPVTWP
160
GSGREAFTNP RAISTDV
Length:167
Mass (Da):17,641
Last modified:December 1, 2001 - v1
Checksum:i8BF4D4A6C59046F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY902195 mRNA. Translation: AAX07133.1.
AB299025 mRNA. Translation: BAF96730.1.
AK292432 mRNA. Translation: BAF85121.1.
AK313887 mRNA. Translation: BAG36612.1.
AL359853 Genomic DNA. No translation available.
CH471067 Genomic DNA. Translation: EAW91055.1.
BC009382 mRNA. Translation: AAH09382.1.
CCDSiCCDS1333.1.
RefSeqiNP_001316641.1. NM_001329712.1.
NP_001316642.1. NM_001329713.1.
NP_001316643.1. NM_001329714.1.
NP_001316644.1. NM_001329715.1.
NP_001316645.1. NM_001329716.1.
NP_001316646.1. NM_001329717.1.
NP_001316647.1. NM_001329718.1.
NP_001316648.1. NM_001329719.1.
NP_775780.1. NM_173509.2.
XP_006711237.1. XM_006711174.2.
XP_006711238.1. XM_006711175.2.
XP_006711240.1. XM_006711177.1.
XP_011507519.1. XM_011509217.1.
XP_016855875.1. XM_017000386.1.
XP_016855876.1. XM_017000387.1.
XP_016855877.1. XM_017000388.1.
XP_016855878.1. XM_017000389.1.
XP_016855879.1. XM_017000390.1.
XP_016855880.1. XM_017000391.1.
XP_016855881.1. XM_017000392.1.
XP_016855882.1. XM_017000393.1.
UniGeneiHs.400696.
Hs.729631.

Genome annotation databases

EnsembliENST00000341785; ENSP00000354891; ENSG00000143340.
GeneIDi148753.
KEGGihsa:148753.
UCSCiuc001gnj.3. human.

Similar proteinsi

Entry informationi

Entry nameiF163A_HUMAN
AccessioniPrimary (citable) accession number: Q96GL9
Secondary accession number(s): A8K8R7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: December 1, 2001
Last modified: September 27, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
  4. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries