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Protein
Submitted name:

Chromaffin granule amine transporter

Gene

SLC18A1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Chromaffin granule amine transporterImported
Submitted name:
SLC18A1 proteinImported
Gene namesi
Name:SLC18A1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000036565.14
HGNCiHGNC:10934 SLC18A1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei21 – 45HelicalSequence analysisAdd BLAST25
Transmembranei164 – 186HelicalSequence analysisAdd BLAST23
Transmembranei198 – 220HelicalSequence analysisAdd BLAST23
Transmembranei232 – 253HelicalSequence analysisAdd BLAST22
Transmembranei260 – 281HelicalSequence analysisAdd BLAST22
Transmembranei301 – 326HelicalSequence analysisAdd BLAST26
Transmembranei338 – 357HelicalSequence analysisAdd BLAST20
Transmembranei363 – 383HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000036565
PharmGKBiPA324

Expressioni

Gene expression databases

BgeeiENSG00000036565

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 385MFSInterPro annotationAdd BLAST363

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3764 Eukaryota
ENOG410XW69 LUCA
GeneTreeiENSGT00390000003851
HOGENOMiHOG000018545
HOVERGENiHBG055082
KOiK08155

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
IPR004734 Multidrug-R
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
SUPFAMiSSF103473 SSF103473, 2 hits
TIGRFAMsiTIGR00880 2_A_01_02, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit

Sequencei

Sequence statusi: Complete.

Q96GL6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRTILDAPQ RLLKEGRASR QLVLVVVFVA LLLDNMLFTV VVPIVPTFLY
60 70 80 90 100
DMEFKEVNSS LHLGHAGSSP HALASPAFST IFSFFNNNTV AVEESVPSGI
110 120 130 140 150
AWMNDTASTI PPPATEAISA HKNNCLQGTG FLEEEITRVG VLFASKAVMQ
160 170 180 190 200
LLVNPFVGPL TNRIGYHIPM FAGFVIMFLS TVMFAFSGTY TLLFVARTLQ
210 220 230 240 250
GIGSSFSSVA GLGMLASVYT DDHERGRAMG TALGGLALGL LVGAPFGSVM
260 270 280 290 300
YEFVGKSAPF LILAFLALLD GALQLCILQP SKVSPESAKG TPLFMLLKDP
310 320 330 340 350
YILVAAGSIC FANMGVAILE PTLPIWMMQT MCSPKWQLGL AFLPASVSYL
360 370 380
IGTNLFGVLA NKMGRWLCSL IGMLVVGTSL LCLPS
Length:385
Mass (Da):41,172
Last modified:December 1, 2001 - v1
Checksum:iDF4240D7F4CBC2BA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025853 Genomic DNA No translation available.
BC009387 mRNA Translation: AAH09387.1
RefSeqiNP_001129163.1, NM_001135691.2
NP_001135796.1, NM_001142324.1
NP_001135797.1, NM_001142325.1
NP_003044.1, NM_003053.3
UniGeneiHs.158322

Genome annotation databases

EnsembliENST00000517776; ENSP00000428001; ENSG00000036565
GeneIDi6570
KEGGihsa:6570
UCSCiuc064ktt.1 human

Similar proteinsi

Entry informationi

Entry nameiQ96GL6_HUMAN
AccessioniPrimary (citable) accession number: Q96GL6
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: March 28, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health