Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Chromaffin granule amine transporter

Gene

SLC18A1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Chromaffin granule amine transporterImported
Submitted name:
SLC18A1 proteinImported
Gene namesi
Name:SLC18A1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

HGNCiHGNC:10934. SLC18A1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei21 – 45HelicalSequence analysisAdd BLAST25
Transmembranei164 – 186HelicalSequence analysisAdd BLAST23
Transmembranei198 – 220HelicalSequence analysisAdd BLAST23
Transmembranei232 – 253HelicalSequence analysisAdd BLAST22
Transmembranei260 – 281HelicalSequence analysisAdd BLAST22
Transmembranei301 – 326HelicalSequence analysisAdd BLAST26
Transmembranei338 – 357HelicalSequence analysisAdd BLAST20
Transmembranei363 – 383HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000036565.
PharmGKBiPA324.

Expressioni

Gene expression databases

BgeeiENSG00000036565.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000276373.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 385MFSInterPro annotationAdd BLAST363

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3764. Eukaryota.
ENOG410XW69. LUCA.
GeneTreeiENSGT00390000003851.
HOGENOMiHOG000018545.
HOVERGENiHBG055082.
KOiK08155.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR004734. Multidrug-R.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 2 hits.
TIGRFAMsiTIGR00880. 2_A_01_02. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q96GL6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRTILDAPQ RLLKEGRASR QLVLVVVFVA LLLDNMLFTV VVPIVPTFLY
60 70 80 90 100
DMEFKEVNSS LHLGHAGSSP HALASPAFST IFSFFNNNTV AVEESVPSGI
110 120 130 140 150
AWMNDTASTI PPPATEAISA HKNNCLQGTG FLEEEITRVG VLFASKAVMQ
160 170 180 190 200
LLVNPFVGPL TNRIGYHIPM FAGFVIMFLS TVMFAFSGTY TLLFVARTLQ
210 220 230 240 250
GIGSSFSSVA GLGMLASVYT DDHERGRAMG TALGGLALGL LVGAPFGSVM
260 270 280 290 300
YEFVGKSAPF LILAFLALLD GALQLCILQP SKVSPESAKG TPLFMLLKDP
310 320 330 340 350
YILVAAGSIC FANMGVAILE PTLPIWMMQT MCSPKWQLGL AFLPASVSYL
360 370 380
IGTNLFGVLA NKMGRWLCSL IGMLVVGTSL LCLPS
Length:385
Mass (Da):41,172
Last modified:December 1, 2001 - v1
Checksum:iDF4240D7F4CBC2BA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025853 Genomic DNA. No translation available.
BC009387 mRNA. Translation: AAH09387.1.
RefSeqiNP_001129163.1. NM_001135691.2.
NP_001135796.1. NM_001142324.1.
NP_001135797.1. NM_001142325.1.
NP_003044.1. NM_003053.3.
UniGeneiHs.158322.

Genome annotation databases

EnsembliENST00000517776; ENSP00000428001; ENSG00000036565.
GeneIDi6570.
KEGGihsa:6570.
UCSCiuc064ktt.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025853 Genomic DNA. No translation available.
BC009387 mRNA. Translation: AAH09387.1.
RefSeqiNP_001129163.1. NM_001135691.2.
NP_001135796.1. NM_001142324.1.
NP_001135797.1. NM_001142325.1.
NP_003044.1. NM_003053.3.
UniGeneiHs.158322.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000276373.

Protocols and materials databases

DNASUi6570.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000517776; ENSP00000428001; ENSG00000036565.
GeneIDi6570.
KEGGihsa:6570.
UCSCiuc064ktt.1. human.

Organism-specific databases

CTDi6570.
HGNCiHGNC:10934. SLC18A1.
OpenTargetsiENSG00000036565.
PharmGKBiPA324.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3764. Eukaryota.
ENOG410XW69. LUCA.
GeneTreeiENSGT00390000003851.
HOGENOMiHOG000018545.
HOVERGENiHBG055082.
KOiK08155.

Miscellaneous databases

GenomeRNAii6570.

Gene expression databases

BgeeiENSG00000036565.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR004734. Multidrug-R.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 2 hits.
TIGRFAMsiTIGR00880. 2_A_01_02. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ96GL6_HUMAN
AccessioniPrimary (citable) accession number: Q96GL6
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: November 30, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.