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Protein
Submitted name:

MTF2 protein

Gene

MTF2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
MTF2 proteinImported
Submitted name:
Metal-response element-binding transcription factor 2Imported
Gene namesi
Name:MTF2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:29535. MTF2.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000143033.
PharmGKBiPA128394586.

Expressioni

Gene expression databases

ExpressionAtlasiQ96G26. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini102 – 157PHD-typeInterPro annotationAdd BLAST56

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00390000009222.
HOVERGENiHBG004755.

Family and domain databases

Gene3Di3.30.40.10. 2 hits.
InterProiView protein in InterPro
IPR025894. Mtf2_C_dom.
IPR002999. Tudor.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
PfamiView protein in Pfam
PF14061. Mtf2_C. 1 hit.
PF00628. PHD. 1 hit.
SMARTiView protein in SMART
SM00249. PHD. 2 hits.
SM00333. TUDOR. 1 hit.
SUPFAMiSSF57903. SSF57903. 2 hits.
PROSITEiView protein in PROSITE
PS01359. ZF_PHD_1. 1 hit.
PS50016. ZF_PHD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q96G26-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRDSTGAGNS LVHKRSPLRR NQKTPTSLTK LSLQDGHKAK KPACKFEEGQ
60 70 80 90 100
DVLARWSDGL FYLGTIKKIN ILKQSCFIIF EDSSKSWVLW KDIQTGATGS
110 120 130 140 150
GEMVCTICQE EYSEAPNEMV ICDKCGQGYH QLCHTPHIDS SVIDSDEKWL
160 170 180 190 200
CRQCVFATTT KRGGALKKGP NAKALQVMKQ TLPYSVADLE WDAGHKTNVQ
210 220 230 240 250
QCYCYCGGPG DWYLKMLQCC KCKQWFHEAC VQCLQKPMLF GDRFYTFICS
260 270 280 290 300
VCSSGPEYLK RLPLQWVDIA HLCLYNLSVI HKKKYFDSEL ELMTYINENW
310 320 330 340 350
DRLHPGELAD TPKSERYEHV LEALNDYKTM EVSNGIEKKG KKKSVGRPPG
360 370 380 390 400
PYTRKMIQKT AEPLLDKESI SENPTLDLPC SIGRTEGTAH SSNTSDVDFT
410 420 430 440 450
GASSAKETTS SSISRHYGLS DSRKRTRTGR SWPAAIPHLR RRRGRLPRRA
460 470 480 490 500
LQTQNSEIVK DDEGKEDYQF DELNTEILNN LADQELQLNH LKNSITSYFG
510 520 530
AAGRIACGEK YRVLARRVTL DGKVQYLVEW EGATAS
Length:536
Mass (Da):60,649
Last modified:December 1, 2001 - v1
Checksum:iD8ED11FC52648AF9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093577 Genomic DNA. No translation available.
AL117354 Genomic DNA. No translation available.
KF459519 Genomic DNA. No translation available.
BC010013 mRNA. Translation: AAH10013.1.
RefSeqiNP_001157864.1. NM_001164392.1.
UniGeneiHs.31016.

Genome annotation databases

EnsembliENST00000370303; ENSP00000359326; ENSG00000143033.
GeneIDi22823.
UCSCiuc009wdk.4. human.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ96G26_HUMAN
AccessioniPrimary (citable) accession number: Q96G26
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: July 5, 2017
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported