Q96G01 (BICD1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein bicaudal D homolog 1
Short name=Bic-D 1

Gene names

Name:

BICD1

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	975 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex.
Subunit structure	Interacts with RAB6A. Interacts (via C-terminus) with RAB6B (GTP-bound); the interaction is direct. Interacts with CLIP-115 and KIFC2 By similarity. Interacts with human cytomegalovirus/HHV-5 protein UL32. Ref.7 Ref.8
Subcellular location	Golgi apparatus.
Tissue specificity	Expressed in the brain, heart and skeletal muscle.
Post-translational modification	Isoform 3 is phosphorylated on Ser-865 and Thr-866.
Sequence similarities	Belongs to the BicD family.

Ontologies

Keywords
Biological process	Host-virus interaction
Cellular component	Golgi apparatus
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Coiled coil
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	RNA processing Traceable author statement Ref.1. Source: ProtInc anatomical structure morphogenesis Traceable author statement Ref.1. Source: ProtInc intracellular mRNA localization Non-traceable author statement Ref.1. Source: UniProtKB microtubule anchoring at microtubule organizing center Inferred from sequence or structural similarity PubMed 19825938. Source: BHF-UCL minus-end-directed organelle transport along microtubule Inferred from mutant phenotype Ref.6. Source: BHF-UCL negative regulation of phospholipase C activity Inferred from sequence or structural similarity. Source: BHF-UCL negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway Inferred from sequence or structural similarity. Source: BHF-UCL positive regulation of receptor-mediated endocytosis Inferred from mutant phenotype PubMed 20164183. Source: BHF-UCL protein localization to organelle Inferred from direct assay Ref.6Ref.8. Source: BHF-UCL regulation of proteinase activated receptor activity Inferred from sequence or structural similarity. Source: BHF-UCL stress granule assembly Inferred from sequence or structural similarity. Source: BHF-UCL viral reproduction Inferred from mutant phenotype Ref.8. Source: BHF-UCL virus-host interaction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	Golgi apparatus Inferred from electronic annotation. Source: UniProtKB-SubCell cytoplasmic vesicle Inferred from direct assay Ref.6Ref.8. Source: BHF-UCL cytoskeleton Non-traceable author statement Ref.1. Source: UniProtKB cytosol Inferred from direct assay Ref.6. Source: BHF-UCL host cell viral assembly compartment Inferred from direct assay Ref.8. Source: BHF-UCL membrane Inferred from direct assay Ref.6. Source: BHF-UCL perinuclear region of cytoplasm Inferred from direct assay Ref.8. Source: BHF-UCL trans-Golgi network Inferred from direct assay Ref.6Ref.8. Source: BHF-UCL
Molecular_function	cytoskeletal adaptor activity Inferred from direct assay Ref.6. Source: BHF-UCL dynactin binding Inferred from direct assay Ref.6. Source: BHF-UCL dynein binding Inferred from direct assay Ref.6. Source: BHF-UCL proteinase activated receptor binding Inferred from sequence or structural similarity PubMed 20164183. Source: BHF-UCL structural constituent of cytoskeleton Traceable author statement Ref.1. Source: ProtInc
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
STAT3	P40763	2	EBI-1104509,EBI-518675

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q96G01-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q96G01-2)

The sequence of this isoform differs from the canonical sequence as follows:
     72-93: AFGQSFSIHRKVAEDGETREET → VSCLSPLPFLALTPPTRKAHSS
     94-975: Missing.

Note: Due to intron retention. No experimental confirmation available.

Isoform 3 (identifier: Q96G01-3)

The sequence of this isoform differs from the canonical sequence as follows:
     858-873: QFSPSLCDQSRPRTSG → YACSDLHSTVQWPDFS
     874-975: Missing.

Note: Due to intron retention.

Isoform 4 (identifier: Q96G01-4)

The sequence of this isoform differs from the canonical sequence as follows:
     821-835: VSGEASVTVPTIDTY → IVSSLLPPYRHSAHN
     836-975: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 975	975	Protein bicaudal D homolog 1		PRO_0000205357
Regions
	Region	663 – 803	141	Interacts with RAB6A
	Coiled coil	1 – 265	265	Potential
	Coiled coil	319 – 496	178	Potential
	Coiled coil	663 – 803	141	Potential
Natural variations
	Alternative sequence	72 – 93	22	AFGQS…TREET → VSCLSPLPFLALTPPTRKAH SS in isoform 2.		VSP_007961
	Alternative sequence	94 – 975	882	Missing in isoform 2.		VSP_007962
	Alternative sequence	821 – 835	15	VSGEA…TIDTY → IVSSLLPPYRHSAHN in isoform 4.		VSP_045637
	Alternative sequence	836 – 975	140	Missing in isoform 4.		VSP_045638
	Alternative sequence	858 – 873	16	QFSPS…PRTSG → YACSDLHSTVQWPDFS in isoform 3.		VSP_007963
	Alternative sequence	874 – 975	102	Missing in isoform 3.		VSP_007964
	Natural variant	778	1	T → A. Ref.2 Corresponds to variant rs200845476 [ dbSNP | Ensembl ].		VAR_069060
Experimental info
	Sequence conflict	588	1	A → P in AAB94805. Ref.1
	Sequence conflict	746	1	A → T in AAB94805. Ref.1
	Sequence conflict	796	1	D → G in AAB94806. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified October 14, 2008. Version 3. Checksum: CCF0FB12013AA294	FASTA	975	110,750
	10 20 30 40 50 60 MAAEEVLQTV DHYKTEIERL TKELTETTHE KIQAAEYGLV VLEEKLTLKQ QYDELEAEYD 70 80 90 100 110 120 SLKQELEQLK EAFGQSFSIH RKVAEDGETR EETLLQESAS KEAYYLGKIL EMQNELKQSR 130 140 150 160 170 180 AVVTNVQAEN ERLTAVVQDL KENNEMVELQ RIRMKDEIRE YKFREARLLQ DYTELEEENI 190 200 210 220 230 240 TLQKLVSTLK QNQVEYEGLK HEIKRFEEET VLLNSQLEDA IRLKEIAEHQ LEEALETLKN 250 260 270 280 290 300 EREQKNNLRK ELSQYISLND NHISISVDGL KFAEDGSEPN NDDKMNGHIH GPLVKLNGDY 310 320 330 340 350 360 RTPTLRKGES LNPVSDLFSE LNISEIQKLK QQLMQVEREK AILLANLQES QTQLEHTKGA 370 380 390 400 410 420 LTEQHERVHR LTEHVNAMRG LQSSKELKAE LDGEKGRDSG EEAHDYEVDI NGLEILECKY 430 440 450 460 470 480 RVAVTEVIDL KAEIKALKEK YNKSVENYTD EKAKYESKIQ MYDEQVTSLE KTTKESGEKM 490 500 510 520 530 540 AHMEKELQKM TSIANENHST LNTAQDELVT FSEELAQLYH HVCLCNNETP NRVMLDYYRQ 550 560 570 580 590 600 SRVTRSGSLK GPDDPRGLLS PRLARRGVSS PVETRTSSEP VAKESTEASK EPSPTKTPTI 610 620 630 640 650 660 SPVITAPPSS PVLDTSDIRK EPMNIYNLNA IIRDQIKHLQ KAVDRSLQLS RQRAAARELA 670 680 690 700 710 720 PMIDKDKEAL MEEILKLKSL LSTKREQIAT LRAVLKANKQ TAEVALANLK NKYENEKAMV 730 740 750 760 770 780 TETMTKLRNE LKALKEDAAT FSSLRAMFAT RCDEYVTQLD EMQRQLAAAE DEKKTLNTLL 790 800 810 820 830 840 RMAIQQKLAL TQRLEDLEFD HEQSRRSKGK LGKSKIGSPK VSGEASVTVP TIDTYLLHSQ 850 860 870 880 890 900 GPQTPNIRVS SGTQRKRQFS PSLCDQSRPR TSGASYLQNL LRVPPDPTST ESFLLKGPPS 910 920 930 940 950 960 MSEFIQGHRL SKEKRLTVAP PDCQQPAASV PPQCSQLAGR QDCPTVSPDT ALPEEQPHSS 970 SQCAPLHCLS KPPHP
	Isoform 2 [UniParc]. Checksum: 2D3BAD41EA5BF9F1	FASTA	93	10,689
	10 20 30 40 50 60 MAAEEVLQTV DHYKTEIERL TKELTETTHE KIQAAEYGLV VLEEKLTLKQ QYDELEAEYD 70 80 90 SLKQELEQLK EVSCLSPLPF LALTPPTRKA HSS
	Isoform 3 [UniParc]. Checksum: 71F286342CB246F9	FASTA	873	99,868
	10 20 30 40 50 60 MAAEEVLQTV DHYKTEIERL TKELTETTHE KIQAAEYGLV VLEEKLTLKQ QYDELEAEYD 70 80 90 100 110 120 SLKQELEQLK EAFGQSFSIH RKVAEDGETR EETLLQESAS KEAYYLGKIL EMQNELKQSR 130 140 150 160 170 180 AVVTNVQAEN ERLTAVVQDL KENNEMVELQ RIRMKDEIRE YKFREARLLQ DYTELEEENI 190 200 210 220 230 240 TLQKLVSTLK QNQVEYEGLK HEIKRFEEET VLLNSQLEDA IRLKEIAEHQ LEEALETLKN 250 260 270 280 290 300 EREQKNNLRK ELSQYISLND NHISISVDGL KFAEDGSEPN NDDKMNGHIH GPLVKLNGDY 310 320 330 340 350 360 RTPTLRKGES LNPVSDLFSE LNISEIQKLK QQLMQVEREK AILLANLQES QTQLEHTKGA 370 380 390 400 410 420 LTEQHERVHR LTEHVNAMRG LQSSKELKAE LDGEKGRDSG EEAHDYEVDI NGLEILECKY 430 440 450 460 470 480 RVAVTEVIDL KAEIKALKEK YNKSVENYTD EKAKYESKIQ MYDEQVTSLE KTTKESGEKM 490 500 510 520 530 540 AHMEKELQKM TSIANENHST LNTAQDELVT FSEELAQLYH HVCLCNNETP NRVMLDYYRQ 550 560 570 580 590 600 SRVTRSGSLK GPDDPRGLLS PRLARRGVSS PVETRTSSEP VAKESTEASK EPSPTKTPTI 610 620 630 640 650 660 SPVITAPPSS PVLDTSDIRK EPMNIYNLNA IIRDQIKHLQ KAVDRSLQLS RQRAAARELA 670 680 690 700 710 720 PMIDKDKEAL MEEILKLKSL LSTKREQIAT LRAVLKANKQ TAEVALANLK NKYENEKAMV 730 740 750 760 770 780 TETMTKLRNE LKALKEDAAT FSSLRAMFAT RCDEYVTQLD EMQRQLAAAE DEKKTLNTLL 790 800 810 820 830 840 RMAIQQKLAL TQRLEDLEFD HEQSRRSKGK LGKSKIGSPK VSGEASVTVP TIDTYLLHSQ 850 860 870 GPQTPNIRVS SGTQRKRYAC SDLHSTVQWP DFS
	Isoform 4 [UniParc]. Checksum: 81A4A7FCCB1D7613	FASTA	835	95,739
	10 20 30 40 50 60 MAAEEVLQTV DHYKTEIERL TKELTETTHE KIQAAEYGLV VLEEKLTLKQ QYDELEAEYD 70 80 90 100 110 120 SLKQELEQLK EAFGQSFSIH RKVAEDGETR EETLLQESAS KEAYYLGKIL EMQNELKQSR 130 140 150 160 170 180 AVVTNVQAEN ERLTAVVQDL KENNEMVELQ RIRMKDEIRE YKFREARLLQ DYTELEEENI 190 200 210 220 230 240 TLQKLVSTLK QNQVEYEGLK HEIKRFEEET VLLNSQLEDA IRLKEIAEHQ LEEALETLKN 250 260 270 280 290 300 EREQKNNLRK ELSQYISLND NHISISVDGL KFAEDGSEPN NDDKMNGHIH GPLVKLNGDY 310 320 330 340 350 360 RTPTLRKGES LNPVSDLFSE LNISEIQKLK QQLMQVEREK AILLANLQES QTQLEHTKGA 370 380 390 400 410 420 LTEQHERVHR LTEHVNAMRG LQSSKELKAE LDGEKGRDSG EEAHDYEVDI NGLEILECKY 430 440 450 460 470 480 RVAVTEVIDL KAEIKALKEK YNKSVENYTD EKAKYESKIQ MYDEQVTSLE KTTKESGEKM 490 500 510 520 530 540 AHMEKELQKM TSIANENHST LNTAQDELVT FSEELAQLYH HVCLCNNETP NRVMLDYYRQ 550 560 570 580 590 600 SRVTRSGSLK GPDDPRGLLS PRLARRGVSS PVETRTSSEP VAKESTEASK EPSPTKTPTI 610 620 630 640 650 660 SPVITAPPSS PVLDTSDIRK EPMNIYNLNA IIRDQIKHLQ KAVDRSLQLS RQRAAARELA 670 680 690 700 710 720 PMIDKDKEAL MEEILKLKSL LSTKREQIAT LRAVLKANKQ TAEVALANLK NKYENEKAMV 730 740 750 760 770 780 TETMTKLRNE LKALKEDAAT FSSLRAMFAT RCDEYVTQLD EMQRQLAAAE DEKKTLNTLL 790 800 810 820 830 RMAIQQKLAL TQRLEDLEFD HEQSRRSKGK LGKSKIGSPK IVSSLLPPYR HSAHN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A human homologue (BICD1) of the Drosophila bicaudal-D gene." Baens M., Marynen P. Genomics 45:601-606(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), NUCLEOTIDE SEQUENCE [MRNA] OF 702-975 (ISOFORM 3).
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 4), VARIANT ALA-778. Tissue: Cerebellum and Thalamus.
[3]	"The finished DNA sequence of human chromosome 12." Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R. , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A. Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2). Tissue: Skin.
[6]	"Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex." Matanis T., Akhmanova A., Wulf P., Del Nery E., Weide T., Stepanova T., Galjart N., Grosveld F., Goud B., De Zeeuw C.I., Barnekow A., Hoogenraad C.C. Nat. Cell Biol. 4:986-992(2002) [PubMed] [Europe PMC] [Abstract] Cited for: CHARACTERIZATION.
[7]	"A role for the Rab6B Bicaudal-D1 interaction in retrograde transport in neuronal cells." Wanschers B.F.J.F., van de Vorstenbosch R., Schlager M.A., Splinter D., Akhmanova A., Hoogenraad C.C., Wieringa B., Fransen J.A. Exp. Cell Res. 313:3408-3420(2007) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH RAB6B.
[8]	"Bicaudal D1-dependent trafficking of human cytomegalovirus tegument protein pp150 in virus-infected cells." Indran S.V., Ballestas M.E., Britt W.J. J. Virol. 84:3162-3177(2010) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH HHV-5 PROTEIN UL32.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U90028 mRNA. Translation: AAB94805.1. U90030 mRNA. Translation: AAB94806.1. AK290188 mRNA. Translation: BAF82877.1. AK313430 mRNA. No translation available. AC016954 Genomic DNA. No translation available. AC026356 Genomic DNA. No translation available. AC048344 Genomic DNA. No translation available. AC087245 Genomic DNA. No translation available. AC087316 Genomic DNA. No translation available. CH471116 Genomic DNA. Translation: EAW88534.1. BC010091 mRNA. No translation available.
IPI	IPI00018368. IPI00062115. IPI00337563. IPI00794021.
RefSeq	NP_001003398.1. NM_001003398.1. NP_001705.2. NM_001714.2.
UniGene	Hs.505202.
3D structure databases
ProteinModelPortal	Q96G01.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q96G01. 5 interactions.
MINT	MINT-206187.
STRING	9606.ENSP00000281474.
PTM databases
PhosphoSite	Q96G01.
Polymorphism databases
DMDM	209572759.
Proteomic databases
PaxDb	Q96G01.
PRIDE	Q96G01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000281474; ENSP00000281474; ENSG00000151746. ENST00000548411; ENSP00000446793; ENSG00000151746. ENST00000551848; ENSP00000448933; ENSG00000151746.
GeneID	636.
KEGG	hsa:636.
UCSC	uc001rku.3. human.
Organism-specific databases
CTD	636.
GeneCards	GC12P032259.
H-InvDB	HIX0010532.
HGNC	HGNC:1049. BICD1.
HPA	HPA041309.
MIM	602204. gene.
neXtProt	NX_Q96G01.
PharmGKB	PA25352.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG291306.
HOGENOM	HOG000261658.
HOVERGEN	HBG050686.
InParanoid	Q96G01.
OMA	QIKHLQR.
PhylomeDB	Q96G01.
Gene expression databases
ArrayExpress	Q96G01.
Bgee	Q96G01.
CleanEx	HS_BICD1.
Genevestigator	Q96G01.
GermOnline	ENSG00000151746. Homo sapiens.
Family and domain databases
InterPro	IPR018477. Bicaudal-D_microtubule-assoc. [Graphical view]
PANTHER	PTHR31233. PTHR31233. 1 hit.
Pfam	PF09730. BicD. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	BICD1. human.
GenomeRNAi	636.
NextBio	2572.
SOURCE	Search...

Entry information

Entry name

BICD1_HUMAN

Accession

Primary (citable) accession number: Q96G01
Secondary accession number(s): A8K2C3 , F8W113, O43892, O43893

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 15, 2003
Last sequence update:	October 14, 2008
Last modified:	May 1, 2013
This is version 94 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.