Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative D-tyrosyl-tRNA(Tyr) deacylase 2

Gene

DTD2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (Potential).Curated

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative D-tyrosyl-tRNA(Tyr) deacylase 2 (EC:3.1.-.-)
Alternative name(s):
Putative D-tyrosyl-tRNA deacylase 2
Gene namesi
Name:DTD2
Synonyms:C14orf126
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000129480.12.
HGNCiHGNC:20277. DTD2.
neXtProtiNX_Q96FN9.

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000129480.
PharmGKBiPA134963117.

Polymorphism and mutation databases

BioMutaiDTD2.
DMDMi74731729.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002540491 – 168Putative D-tyrosyl-tRNA(Tyr) deacylase 2Add BLAST168

Proteomic databases

EPDiQ96FN9.
MaxQBiQ96FN9.
PaxDbiQ96FN9.
PeptideAtlasiQ96FN9.
PRIDEiQ96FN9.

PTM databases

iPTMnetiQ96FN9.
PhosphoSitePlusiQ96FN9.

Expressioni

Gene expression databases

BgeeiENSG00000129480.
CleanExiHS_C14orf126.
ExpressionAtlasiQ96FN9. baseline and differential.
GenevisibleiQ96FN9. HS.

Organism-specific databases

HPAiHPA001117.

Interactioni

Protein-protein interaction databases

BioGridi125191. 3 interactors.
IntActiQ96FN9. 1 interactor.
STRINGi9606.ENSP00000312224.

Structurei

3D structure databases

ProteinModelPortaliQ96FN9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DTD family.Curated

Phylogenomic databases

eggNOGiKOG3323. Eukaryota.
COG1490. LUCA.
GeneTreeiENSGT00390000003234.
HOGENOMiHOG000113983.
HOVERGENiHBG081465.
InParanoidiQ96FN9.
OMAiIYICFFK.
OrthoDBiEOG091G0WKW.
PhylomeDBiQ96FN9.
TreeFamiTF329119.

Family and domain databases

Gene3Di3.50.80.10. 1 hit.
InterProiView protein in InterPro
IPR003732. Daa-tRNA_deacyls_DTD.
IPR023509. DTD-like_sf.
PANTHERiPTHR10472. PTHR10472. 1 hit.
PfamiView protein in Pfam
PF02580. Tyr_Deacylase. 1 hit.
SUPFAMiSSF69500. SSF69500. 1 hit.

Sequencei

Sequence statusi: Complete.

Q96FN9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEGSRIPQA RALLQQCLHA RLQIRPADGD VAAQWVEVQR GLVIYVCFFK
60 70 80 90 100
GADKELLPKM VNTLLNVKLS ETENGKHVSI LDLPGNILII PQATLGGRLK
110 120 130 140 150
GRNMQYHSNS GKEEGFELYS QFVTLCEKEV AANSKCAEAR VVVEHGTYGN
160
RQVLKLDTNG PFTHLIEF
Length:168
Mass (Da):18,660
Last modified:December 1, 2001 - v1
Checksum:iF74D05F238C8D0A9
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_0288026R → W. Corresponds to variant dbSNP:rs17097904Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL139353 Genomic DNA. No translation available.
AL163973 Genomic DNA. No translation available.
CH471078 Genomic DNA. Translation: EAW65944.1.
CH471078 Genomic DNA. Translation: EAW65945.1.
BC010618 mRNA. Translation: AAH10618.1.
CCDSiCCDS9643.1.
RefSeqiNP_542395.1. NM_080664.2.
UniGeneiHs.116014.

Genome annotation databases

EnsembliENST00000310850; ENSP00000312224; ENSG00000129480.
ENST00000356180; ENSP00000348503; ENSG00000129480.
GeneIDi112487.
KEGGihsa:112487.
UCSCiuc001wrj.5. human.

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiDTD2_HUMAN
AccessioniPrimary (citable) accession number: Q96FN9
Secondary accession number(s): D3DS87
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: December 1, 2001
Last modified: February 28, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome