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Protein

Coiled-coil domain-containing protein 97

Gene

CCDC97

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Coiled-coil domain-containing protein 97
Gene namesi
Name:CCDC97
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000142039.3.
HGNCiHGNC:28289. CCDC97.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

DisGeNETi90324.
OpenTargetsiENSG00000142039.
PharmGKBiPA144596464.

Polymorphism and mutation databases

BioMutaiCCDC97.
DMDMi74731660.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002860961 – 343Coiled-coil domain-containing protein 97Add BLAST343

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineCombined sources1
Modified residuei47PhosphothreonineCombined sources1
Modified residuei275PhosphoserineCombined sources1
Modified residuei337PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ96F63.
MaxQBiQ96F63.
PaxDbiQ96F63.
PeptideAtlasiQ96F63.
PRIDEiQ96F63.

PTM databases

iPTMnetiQ96F63.
PhosphoSitePlusiQ96F63.

Expressioni

Gene expression databases

BgeeiENSG00000142039.
CleanExiHS_CCDC97.
ExpressionAtlasiQ96F63. baseline and differential.
GenevisibleiQ96F63. HS.

Organism-specific databases

HPAiHPA043320.
HPA043572.

Interactioni

Protein-protein interaction databases

BioGridi124693. 26 interactors.
IntActiQ96F63. 4 interactors.
STRINGi9606.ENSP00000269967.

Structurei

3D structure databases

ProteinModelPortaliQ96F63.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili224 – 262Sequence analysisAdd BLAST39

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG3044. Eukaryota.
ENOG4111QQ2. LUCA.
GeneTreeiENSGT00390000015495.
HOGENOMiHOG000246995.
HOVERGENiHBG059629.
InParanoidiQ96F63.
OMAiMMQRAPD.
OrthoDBiEOG091G0MCZ.
PhylomeDBiQ96F63.
TreeFamiTF316152.

Family and domain databases

InterProiView protein in InterPro
IPR018613. DUF2052_coiled-coil.
PfamiView protein in Pfam
PF09747. DUF2052. 1 hit.

Sequencei

Sequence statusi: Complete.

Q96F63-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEAVATATAA KEPDKGCIEP GPGHWGELSR TPVPSKPQDK VEAAEATPVA
60 70 80 90 100
LDSDTSGAEN AAVSAMLHAV AASRLPVCSQ QQGEPDLTEH EKVAILAQLY
110 120 130 140 150
HEKPLVFLER FRTGLREEHL ACFGHVRGDH RADFYCAEVA RQGTARPRTL
160 170 180 190 200
RTRLRNRRYA ALRELIQGGE YFSDEQMRFR APLLYEQYIG QYLTQEELSA
210 220 230 240 250
RTPTHQPPKP GSPGRPACPL SNLLLQSYEE RELQQRLLQQ QEEEEACLEE
260 270 280 290 300
EEEEEDSDEE DQRSGKDSEA WVPDSEERLI LREEFTSRMH QRFLDGKDGD
310 320 330 340
FDYSTVDDNP DFDNLDIVAR DEEERYFDEE EPEDAPSPEL DGD
Length:343
Mass (Da):38,947
Last modified:December 1, 2001 - v1
Checksum:i5153E473FF0D2069
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC007575 mRNA. Translation: AAH07575.1.
BC011577 mRNA. Translation: AAH11577.1.
AL833726 mRNA. Translation: CAH56251.1.
CCDSiCCDS12578.1.
RefSeqiNP_443080.1. NM_052848.2.
UniGeneiHs.437497.

Genome annotation databases

EnsembliENST00000269967; ENSP00000269967; ENSG00000142039.
GeneIDi90324.
KEGGihsa:90324.
UCSCiuc002oqg.3. human.

Similar proteinsi

Entry informationi

Entry nameiCCD97_HUMAN
AccessioniPrimary (citable) accession number: Q96F63
Secondary accession number(s): Q658N6, Q96IF3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: December 1, 2001
Last modified: September 27, 2017
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM