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Protein
Submitted name:

GPNMB protein

Gene

GPNMB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
GPNMB proteinImported
Submitted name:
Glycoprotein (Transmembrane) nmbImported
Submitted name:
Glycoprotein (Transmembrane) nmb, isoform CRA_aImported
Submitted name:
Transmembrane glycoprotein NMBImported
Submitted name:
Uncharacterized protein GPNMBImported
Gene namesi
Name:GPNMBImported
ORF Names:hCG_37976Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000136235.15.
HGNCiHGNC:4462. GPNMB.

Subcellular locationi

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000136235.
PharmGKBiPA28845.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501110439223 – 206Sequence analysisAdd BLAST184

Proteomic databases

MaxQBiQ96F58.

Expressioni

Gene expression databases

BgeeiENSG00000136235.

Family & Domainsi

Keywords - Domaini

SignalSequence analysis, TransmembraneImported

Phylogenomic databases

eggNOGiENOG410IE9P. Eukaryota.
ENOG4110Q2V. LUCA.
GeneTreeiENSGT00530000063573.
HOVERGENiHBG071366.

Sequencei

Sequence statusi: Complete.

Q96F58-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MECLYYFLGF LLLAARLPLD AAKRFHDVLG NERPSAYMRE HNQLNGWSSD
60 70 80 90 100
ENDWNEKLYP VWKRGDMRWK NSWKGGRVQA VLTSDSPALV GSNITFAVNL
110 120 130 140 150
IFPRCQKEDA NGNIVYEKNC RNEAGLSADP YVYNWTAWSE DSDGENGTGQ
160 170 180 190 200
SHHNVFPDGK PFPHHPGWRR WNFIYVFHTL GWLLQTPKLL LYLSLKFQPS

LFLLYN
Length:206
Mass (Da):23,945
Last modified:December 1, 2001 - v1
Checksum:i30CBDE6928D73FBD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC011595 mRNA. Translation: AAH11595.1.
AC005082 Genomic DNA. Translation: AAP22337.1.
BT007074 mRNA. Translation: AAP35737.1.
CH471073 Genomic DNA. Translation: EAW93781.1.
RefSeqiNP_002501.1. NM_002510.2.
UniGeneiHs.190495.

Genome annotation databases

EnsembliENST00000409458; ENSP00000386476; ENSG00000136235.
GeneIDi10457.
UCSCiuc003swa.3. human.

Similar proteinsi

Entry informationi

Entry nameiQ96F58_HUMAN
AccessioniPrimary (citable) accession number: Q96F58
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: November 22, 2017
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported