Unreviewed, UniProtKB/TrEMBL Q96EV4 (Q96EV4_HUMAN)

Names and origin

Protein names

Submitted name:
    PIK3R2 protein EMBL AAH11917.2

Gene names

Name:

PIK3R2 EMBL AAH11917.2

Organism

Homo sapiens (Human) EMBL AAH11917.2

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	388 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Biological process	negative regulation of anti-apoptosis Inferred from electronic annotation. Source: Compara
Cellular component	phosphoinositide 3-kinase complex Inferred from electronic annotation. Source: InterPro
Molecular function	1-phosphatidylinositol-3-kinase activity Inferred from electronic annotation. Source: Compara phosphoinositide 3-kinase regulator activity Inferred from electronic annotation. Source: InterPro protein binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAH11917.2

Sequences

	Sequence		Length	Mass (Da)
	Q96EV4-1 [UniParc]. Last modified March 1, 2004. Version 2. Checksum: FFB64582F73803AF	FASTA	388	45,297
	10 20 30 40 50 60 REKLRDTPDG TFLVRDASSK IQGEYTLTLR KGGNNKLIKV FHRDGHYGFS EPLTFCSVVD 70 80 90 100 110 120 LINHYRHESL AQYNAKLDTR LLYPVSKYQQ DQIVKEDSVE AVGAQLKVYH QQYQDKSREY 130 140 150 160 170 180 DQLYEEYTRT SQELQMKRTA IEAFNETIKI FEEQGQTQEK CSKEYLERFR REGNEKEMQR 190 200 210 220 230 240 ILLNSERLKS RIAEIHESRT KLEQQLRAQA SDNREIDKRM NSLKPDLMQL RKIRDQYLVW 250 260 270 280 290 300 LTQKGARQKK INEWLGIKNE TEDQYALMED EDDLPHHEER TWYVGKINRT QAEEMLSGKR 310 320 330 340 350 360 DGTFLIRESS QRGCYACSVV VDGDTKHCVI YRTATGFGFA EPYNLYGSLK ELVLHYQHAS 370 380 LVQHNDALTV TLAHPVRAPG PGPPPAAR

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Kidney EMBL AAH11917.2.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC011917 mRNA. Translation: AAH11917.2.
IPI	IPI00011736.
UniGene	Hs.371344
3D structure databases
HSSP	HSSP built from PDB template 1FU6 based on UniProtKB Q63787.
SMR	Q96EV4. Positions 2-96, 88-256, 274-378.
ModBase	Search...
Protein-protein interaction databases
STRING	Q96EV4.
Genome annotation databases
Ensembl	ENST00000222254; ENSP00000222254; ENSG00000105647; Homo sapiens. [Genome view]
Organism-specific databases
HGNC	HGNC:8980. PIK3R2.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q96EV4.
Gene expression databases
ArrayExpress	Q96EV4.
Bgee	Q96EV4.
Family and domain databases
InterPro	IPR001720. PI3kinase_P85. IPR000980. SH2. [Graphical view]
Gene3D	G3DSA:3.30.505.10. SH2. 2 hits.
PANTHER	PTHR10155. PI3kinase_P85. 1 hit.
Pfam	PF00017. SH2. 2 hits. [Graphical view]
PRINTS	PR00678. PI3KINASEP85. PR00401. SH2DOMAIN.
SMART	SM00252. SH2. 2 hits. [Graphical view]
PROSITE	PS50001. SH2. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q96EV4_HUMAN

Accession

Primary (citable) accession number: Q96EV4

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	March 1, 2004
Last modified:	January 19, 2010
This is version 44 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.