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Protein

Protein KTI12 homolog

Gene

KTI12

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi8 – 15ATPSequence analysis8

GO - Molecular functioni

Keywordsi

LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein KTI12 homolog
Gene namesi
Name:KTI12
ORF Names:SBBI81
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000198841.3
HGNCiHGNC:25160 KTI12
neXtProtiNX_Q96EK9

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000198841
PharmGKBiPA142671571

Polymorphism and mutation databases

BioMutaiKTI12
DMDMi74751844

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002856861 – 354Protein KTI12 homologAdd BLAST354

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei184PhosphoserineCombined sources1
Modified residuei200PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ96EK9
MaxQBiQ96EK9
PaxDbiQ96EK9
PeptideAtlasiQ96EK9
PRIDEiQ96EK9

PTM databases

iPTMnetiQ96EK9
PhosphoSitePlusiQ96EK9

Expressioni

Gene expression databases

BgeeiENSG00000198841
CleanExiHS_KTI12
GenevisibleiQ96EK9 HS

Organism-specific databases

HPAiHPA031204
HPA031205

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
FHL3Q136433EBI-7951092,EBI-741101

Protein-protein interaction databases

BioGridi125220, 4 interactors
IntActiQ96EK9, 2 interactors
MINTiQ96EK9
STRINGi9606.ENSP00000360676

Structurei

3D structure databases

ProteinModelPortaliQ96EK9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the KTI12 family.Curated

Phylogenomic databases

eggNOGiKOG3062 Eukaryota
COG4088 LUCA
GeneTreeiENSGT00390000002443
HOGENOMiHOG000247843
HOVERGENiHBG056053
InParanoidiQ96EK9
KOiK15456
OMAiRYQLYCE
OrthoDBiEOG091G0CCR
PhylomeDBiQ96EK9
TreeFamiTF312974

Family and domain databases

InterProiView protein in InterPro
IPR013641 KTI12/PSTK
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF08433 KTI12, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit

Sequencei

Sequence statusi: Complete.

Q96EK9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLVVFCGLP YSGKSRRAEE LRVALAAEGR AVYVVDDAAV LGAEDPAVYG
60 70 80 90 100
DSAREKALRG ALRASVERRL SRHDVVILDS LNYIKGFRYE LYCLARAART
110 120 130 140 150
PLCLVYCVRP GGPIAGPQVA GANENPGRNV SVSWRPRAEE DGRAQAAGSS
160 170 180 190 200
VLRELHTADS VVNGSAQADV PKELEREESG AAESPALVTP DSEKSAKHGS
210 220 230 240 250
GAFYSPELLE ALTLRFEAPD SRNRWDRPLF TLVGLEEPLP LAGIRSALFE
260 270 280 290 300
NRAPPPHQST QSQPLASGSF LHQLDQVTSQ VLAGLMEAQK SAVPGDLLTL
310 320 330 340 350
PGTTEHLRFT RPLTMAELSR LRRQFISYTK MHPNNENLPQ LANMFLQYLS

QSLH
Length:354
Mass (Da):38,616
Last modified:December 1, 2001 - v1
Checksum:i877F297D28AF1E24
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_032046191D → E. Corresponds to variant dbSNP:rs2783175Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF327348 mRNA Translation: AAL56009.1
AL445685 Genomic DNA No translation available.
BC012173 mRNA Translation: AAH12173.1
CCDSiCCDS562.1
RefSeqiNP_612426.1, NM_138417.2
UniGeneiHs.476033

Genome annotation databases

EnsembliENST00000371614; ENSP00000360676; ENSG00000198841
GeneIDi112970
KEGGihsa:112970
UCSCiuc001ctj.2 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiKTI12_HUMAN
AccessioniPrimary (citable) accession number: Q96EK9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: December 1, 2001
Last modified: March 28, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

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