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Protein

60S ribosomal protein L39-like

Gene

RPL39L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • spermatogenesis Source: UniProtKB
  • translation Source: GO_Central
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L39-like
Alternative name(s):
60S ribosomal protein L39-2
Gene namesi
Name:RPL39L
Synonyms:RPL39L1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

HGNCiHGNC:17094. RPL39L.

Subcellular locationi

GO - Cellular componenti

  • cytosolic large ribosomal subunit Source: UniProtKB
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA34744.

Polymorphism and mutation databases

BioMutaiRPL39L.
DMDMi29427944.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 515160S ribosomal protein L39-likePRO_0000127027Add
BLAST

Proteomic databases

PaxDbiQ96EH5.
PRIDEiQ96EH5.
TopDownProteomicsiQ96EH5.

Expressioni

Tissue specificityi

Testis specific.

Gene expression databases

BgeeiQ96EH5.
CleanExiHS_RPL39L.
GenevisibleiQ96EH5. HS.

Organism-specific databases

HPAiCAB004658.
HPA047105.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CCNDBP1O952733EBI-6658607,EBI-748961

Protein-protein interaction databases

BioGridi125530. 2 interactions.
IntActiQ96EH5. 3 interactions.
STRINGi9606.ENSP00000296277.

Structurei

3D structure databases

ProteinModelPortaliQ96EH5.
SMRiQ96EH5. Positions 1-37.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L39e family.Curated

Phylogenomic databases

eggNOGiKOG0002. Eukaryota.
COG2167. LUCA.
GeneTreeiENSGT00390000014814.
HOGENOMiHOG000230627.
HOVERGENiHBG001245.
InParanoidiQ96EH5.
OMAiKYSSKRH.
OrthoDBiEOG789CF5.
PhylomeDBiQ96EH5.
TreeFamiTF300223.

Family and domain databases

Gene3Di1.10.1620.10. 1 hit.
HAMAPiMF_00629. Ribosomal_L39e.
InterProiIPR000077. Ribosomal_L39.
IPR020083. Ribosomal_L39_CS.
IPR023626. Ribosomal_L39e_dom.
[Graphical view]
PANTHERiPTHR19970. PTHR19970. 1 hit.
PfamiPF00832. Ribosomal_L39. 1 hit.
[Graphical view]
SUPFAMiSSF48662. SSF48662. 1 hit.
PROSITEiPS00051. RIBOSOMAL_L39E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q96EH5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSHKTFTIK RFLAKKQKQN RPIPQWIQMK PGSKIRYNSK RRHWRRTKLG

L
Length:51
Mass (Da):6,293
Last modified:January 23, 2007 - v3
Checksum:i7010DF584034CB2E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L05096 mRNA. Translation: AAC15859.1.
AF548529 mRNA. Translation: AAN52397.1.
AB063607 Genomic DNA. Translation: BAC19834.1.
AB063610 mRNA. Translation: BAC19837.1.
BC012328 mRNA. Translation: AAH12328.1.
CCDSiCCDS3286.1.
RefSeqiNP_443201.1. NM_052969.1.
UniGeneiHs.647900.

Genome annotation databases

EnsembliENST00000296277; ENSP00000296277; ENSG00000163923.
ENST00000433055; ENSP00000389356; ENSG00000163923.
ENST00000455270; ENSP00000397240; ENSG00000163923.
GeneIDi116832.
KEGGihsa:116832.
UCSCiuc003fre.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L05096 mRNA. Translation: AAC15859.1.
AF548529 mRNA. Translation: AAN52397.1.
AB063607 Genomic DNA. Translation: BAC19834.1.
AB063610 mRNA. Translation: BAC19837.1.
BC012328 mRNA. Translation: AAH12328.1.
CCDSiCCDS3286.1.
RefSeqiNP_443201.1. NM_052969.1.
UniGeneiHs.647900.

3D structure databases

ProteinModelPortaliQ96EH5.
SMRiQ96EH5. Positions 1-37.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi125530. 2 interactions.
IntActiQ96EH5. 3 interactions.
STRINGi9606.ENSP00000296277.

Polymorphism and mutation databases

BioMutaiRPL39L.
DMDMi29427944.

Proteomic databases

PaxDbiQ96EH5.
PRIDEiQ96EH5.
TopDownProteomicsiQ96EH5.

Protocols and materials databases

DNASUi116832.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000296277; ENSP00000296277; ENSG00000163923.
ENST00000433055; ENSP00000389356; ENSG00000163923.
ENST00000455270; ENSP00000397240; ENSG00000163923.
GeneIDi116832.
KEGGihsa:116832.
UCSCiuc003fre.2. human.

Organism-specific databases

CTDi116832.
GeneCardsiRPL39L.
HGNCiHGNC:17094. RPL39L.
HPAiCAB004658.
HPA047105.
MIMi607547. gene.
neXtProtiNX_Q96EH5.
PharmGKBiPA34744.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0002. Eukaryota.
COG2167. LUCA.
GeneTreeiENSGT00390000014814.
HOGENOMiHOG000230627.
HOVERGENiHBG001245.
InParanoidiQ96EH5.
OMAiKYSSKRH.
OrthoDBiEOG789CF5.
PhylomeDBiQ96EH5.
TreeFamiTF300223.

Miscellaneous databases

GenomeRNAii116832.
PROiQ96EH5.
SOURCEiSearch...

Gene expression databases

BgeeiQ96EH5.
CleanExiHS_RPL39L.
GenevisibleiQ96EH5. HS.

Family and domain databases

Gene3Di1.10.1620.10. 1 hit.
HAMAPiMF_00629. Ribosomal_L39e.
InterProiIPR000077. Ribosomal_L39.
IPR020083. Ribosomal_L39_CS.
IPR023626. Ribosomal_L39e_dom.
[Graphical view]
PANTHERiPTHR19970. PTHR19970. 1 hit.
PfamiPF00832. Ribosomal_L39. 1 hit.
[Graphical view]
SUPFAMiSSF48662. SSF48662. 1 hit.
PROSITEiPS00051. RIBOSOMAL_L39E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Expressed sequence tags from a human cell line."
    Bhat K.S.
    Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "A human gene encoding a protein homologous to ribosomal protein L39 is normally expressed in the testis and derepressed in multiple cancer cells."
    Nadano D., Notsu T., Matsuda T., Sato T.-A.
    Biochim. Biophys. Acta 1577:430-436(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  3. "Functional second genes generated by retrotransposition of the X-linked ribosomal protein genes."
    Uechi T., Maeda N., Tanaka T., Kenmochi N.
    Nucleic Acids Res. 30:5369-5375(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Uterus.

Entry informationi

Entry nameiRL39L_HUMAN
AccessioniPrimary (citable) accession number: Q96EH5
Secondary accession number(s): Q8IUD0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 28, 2003
Last sequence update: January 23, 2007
Last modified: June 8, 2016
This is version 114 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.