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Q96DU3

- SLAF6_HUMAN

UniProt

Q96DU3 - SLAF6_HUMAN

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Protein
SLAM family member 6
Gene
SLAMF6, KALI, UNQ6123/PRO20080
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors.1 Publication

GO - Molecular functioni

  1. receptor activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Receptor

Names & Taxonomyi

Protein namesi
Recommended name:
SLAM family member 6
Alternative name(s):
Activating NK receptor
NK-T-B-antigen
Short name:
NTB-A
CD_antigen: CD352
Gene namesi
Name:SLAMF6
Synonyms:KALI
ORF Names:UNQ6123/PRO20080
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 1

Organism-specific databases

HGNCiHGNC:21392. SLAMF6.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini22 – 226205Extracellular Reviewed prediction
Add
BLAST
Transmembranei227 – 24721Helical; Reviewed prediction
Add
BLAST
Topological domaini248 – 33184Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. extracellular vesicular exosome Source: UniProt
  2. integral component of membrane Source: UniProtKB-KW
  3. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi108 – 1081R → A: Inhibits dimerization. 1 Publication
Mutagenesisi110 – 1101Q → A: Inhibits dimerization. 1 Publication
Mutagenesisi112 – 1121S → A: Inhibits dimerization. 1 Publication

Organism-specific databases

PharmGKBiPA134959277.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 21211 Publication
Add
BLAST
Chaini22 – 332311SLAM family member 6
PRO_0000014961Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi58 – 581N-linked (GlcNAc...) Reviewed prediction
Glycosylationi87 – 871N-linked (GlcNAc...) Reviewed prediction
Glycosylationi137 – 1371N-linked (GlcNAc...) Reviewed prediction
Glycosylationi144 – 1441N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi147 ↔ 2141 Publication
Disulfide bondi153 ↔ 1951 Publication
Glycosylationi161 – 1611N-linked (GlcNAc...) Reviewed prediction
Glycosylationi171 – 1711N-linked (GlcNAc...); atypical1 Publication
Glycosylationi178 – 1781N-linked (GlcNAc...)1 Publication
Glycosylationi203 – 2031N-linked (GlcNAc...) Reviewed prediction
Modified residuei274 – 2741Phosphotyrosine1 Publication
Modified residuei278 – 2781Phosphoserine1 Publication
Modified residuei309 – 3091Phosphotyrosine1 Publication

Keywords - PTMi

Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

MaxQBiQ96DU3.
PaxDbiQ96DU3.
PRIDEiQ96DU3.

PTM databases

PhosphoSiteiQ96DU3.

Expressioni

Tissue specificityi

Expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes.1 Publication

Gene expression databases

BgeeiQ96DU3.
CleanExiHS_SLAMF6.
GenevestigatoriQ96DU3.

Organism-specific databases

HPAiHPA051363.
HPA051903.

Interactioni

Subunit structurei

Homodimer. Interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP.2 Publications

Protein-protein interaction databases

BioGridi125378. 3 interactions.
STRINGi9606.ENSP00000357038.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi28 – 336
Beta strandi38 – 403
Beta strandi52 – 576
Beta strandi60 – 667
Beta strandi69 – 713
Beta strandi74 – 774
Helixi80 – 834
Beta strandi86 – 883
Beta strandi94 – 963
Helixi101 – 1033
Beta strandi105 – 1128
Beta strandi117 – 12711
Beta strandi131 – 1377
Beta strandi145 – 15713
Beta strandi163 – 1686
Beta strandi171 – 18313
Turni185 – 1873
Beta strandi192 – 1998
Beta strandi202 – 2098
Helixi210 – 2134

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2IF7X-ray3.00A/B/C/D24-215[»]
ProteinModelPortaliQ96DU3.
SMRiQ96DU3. Positions 24-215.

Miscellaneous databases

EvolutionaryTraceiQ96DU3.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini35 – 12086Ig-like V-type
Add
BLAST
Domaini132 – 20978Ig-like C2-type
Add
BLAST

Sequence similaritiesi

Keywords - Domaini

Immunoglobulin domain, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG45125.
HOGENOMiHOG000059581.
HOVERGENiHBG055054.
InParanoidiQ96DU3.
KOiK16852.
OMAiEIHLTCS.
OrthoDBiEOG77HDFC.
PhylomeDBiQ96DU3.
TreeFamiTF334964.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
IPR015631. SLAM_fam_rcpts.
[Graphical view]
PANTHERiPTHR12080. PTHR12080. 1 hit.
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q96DU3-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MLWLFQSLLF VFCFGPGNVV SQSSLTPLMV NGILGESVTL PLEFPAGEKV    50
NFITWLFNET SLAFIVPHET KSPEIHVTNP KQGKRLNFTQ SYSLQLSNLK 100
MEDTGSYRAQ ISTKTSAKLS SYTLRILRQL RNIQVTNHSQ LFQNMTCELH 150
LTCSVEDADD NVSFRWEALG NTLSSQPNLT VSWDPRISSE QDYTCIAENA 200
VSNLSFSVSA QKLCEDVKIQ YTDTKMILFM VSGICIVFGF IILLLLVLRK 250
RRDSLSLSTQ RTQGPAESAR NLEYVSVSPT NNTVYASVTH SNRETEIWTP 300
RENDTITIYS TINHSKESKP TFSRATALDN VV 332
Length:332
Mass (Da):37,345
Last modified:July 22, 2008 - v3
Checksum:i46D8141A0D198091
GO
Isoform 2 (identifier: Q96DU3-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     266-266: Missing.

Show »
Length:331
Mass (Da):37,274
Checksum:i16E2727CEF8306F4
GO
Isoform 3 (identifier: Q96DU3-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     18-128: Missing.

Note: No experimental confirmation available.

Show »
Length:221
Mass (Da):24,976
Checksum:i71CACAED7B8FDDEC
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei18 – 128111Missing in isoform 3.
VSP_043230Add
BLAST
Alternative sequencei266 – 2661Missing in isoform 2.
VSP_034620

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ277141 mRNA. Translation: CAC59749.1.
AJ306388 mRNA. Translation: CAC59750.1.
AY358159 mRNA. Translation: AAQ88526.1.
AL832854 mRNA. Translation: CAI46161.1.
AK125624 mRNA. Translation: BAG54223.1.
AK301026 mRNA. Translation: BAG62642.1.
AK313549 mRNA. Translation: BAG36325.1.
AL138930 Genomic DNA. Translation: CAI15155.1.
AL138930 Genomic DNA. Translation: CAI15156.1.
AL138930 Genomic DNA. Translation: CAI15157.1.
CH471121 Genomic DNA. Translation: EAW52713.1.
CH471121 Genomic DNA. Translation: EAW52715.1.
BC113893 mRNA. Translation: AAI13894.1.
BC114495 mRNA. Translation: AAI14496.1.
CCDSiCCDS1205.1. [Q96DU3-2]
CCDS53393.1. [Q96DU3-3]
CCDS53394.1. [Q96DU3-1]
RefSeqiNP_001171643.1. NM_001184714.1. [Q96DU3-1]
NP_001171644.1. NM_001184715.1.
NP_001171645.1. NM_001184716.1. [Q96DU3-3]
NP_443163.1. NM_052931.4. [Q96DU3-2]
UniGeneiHs.492348.

Genome annotation databases

EnsembliENST00000368055; ENSP00000357034; ENSG00000162739. [Q96DU3-3]
ENST00000368057; ENSP00000357036; ENSG00000162739. [Q96DU3-1]
ENST00000368059; ENSP00000357038; ENSG00000162739. [Q96DU3-2]
GeneIDi114836.
KEGGihsa:114836.
UCSCiuc001fwd.2. human. [Q96DU3-2]
uc001fwe.2. human. [Q96DU3-1]
uc010pji.2. human. [Q96DU3-3]

Polymorphism databases

DMDMi205830927.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ277141 mRNA. Translation: CAC59749.1 .
AJ306388 mRNA. Translation: CAC59750.1 .
AY358159 mRNA. Translation: AAQ88526.1 .
AL832854 mRNA. Translation: CAI46161.1 .
AK125624 mRNA. Translation: BAG54223.1 .
AK301026 mRNA. Translation: BAG62642.1 .
AK313549 mRNA. Translation: BAG36325.1 .
AL138930 Genomic DNA. Translation: CAI15155.1 .
AL138930 Genomic DNA. Translation: CAI15156.1 .
AL138930 Genomic DNA. Translation: CAI15157.1 .
CH471121 Genomic DNA. Translation: EAW52713.1 .
CH471121 Genomic DNA. Translation: EAW52715.1 .
BC113893 mRNA. Translation: AAI13894.1 .
BC114495 mRNA. Translation: AAI14496.1 .
CCDSi CCDS1205.1. [Q96DU3-2 ]
CCDS53393.1. [Q96DU3-3 ]
CCDS53394.1. [Q96DU3-1 ]
RefSeqi NP_001171643.1. NM_001184714.1. [Q96DU3-1 ]
NP_001171644.1. NM_001184715.1.
NP_001171645.1. NM_001184716.1. [Q96DU3-3 ]
NP_443163.1. NM_052931.4. [Q96DU3-2 ]
UniGenei Hs.492348.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2IF7 X-ray 3.00 A/B/C/D 24-215 [» ]
ProteinModelPortali Q96DU3.
SMRi Q96DU3. Positions 24-215.
ModBasei Search...

Protein-protein interaction databases

BioGridi 125378. 3 interactions.
STRINGi 9606.ENSP00000357038.

PTM databases

PhosphoSitei Q96DU3.

Polymorphism databases

DMDMi 205830927.

Proteomic databases

MaxQBi Q96DU3.
PaxDbi Q96DU3.
PRIDEi Q96DU3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000368055 ; ENSP00000357034 ; ENSG00000162739 . [Q96DU3-3 ]
ENST00000368057 ; ENSP00000357036 ; ENSG00000162739 . [Q96DU3-1 ]
ENST00000368059 ; ENSP00000357038 ; ENSG00000162739 . [Q96DU3-2 ]
GeneIDi 114836.
KEGGi hsa:114836.
UCSCi uc001fwd.2. human. [Q96DU3-2 ]
uc001fwe.2. human. [Q96DU3-1 ]
uc010pji.2. human. [Q96DU3-3 ]

Organism-specific databases

CTDi 114836.
GeneCardsi GC01M160454.
HGNCi HGNC:21392. SLAMF6.
HPAi HPA051363.
HPA051903.
MIMi 606446. gene.
neXtProti NX_Q96DU3.
PharmGKBi PA134959277.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG45125.
HOGENOMi HOG000059581.
HOVERGENi HBG055054.
InParanoidi Q96DU3.
KOi K16852.
OMAi EIHLTCS.
OrthoDBi EOG77HDFC.
PhylomeDBi Q96DU3.
TreeFami TF334964.

Miscellaneous databases

EvolutionaryTracei Q96DU3.
GeneWikii SLAMF6.
GenomeRNAii 114836.
NextBioi 79337.
PROi Q96DU3.
SOURCEi Search...

Gene expression databases

Bgeei Q96DU3.
CleanExi HS_SLAMF6.
Genevestigatori Q96DU3.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
IPR015631. SLAM_fam_rcpts.
[Graphical view ]
PANTHERi PTHR12080. PTHR12080. 1 hit.
Pfami PF07686. V-set. 1 hit.
[Graphical view ]
SMARTi SM00409. IG. 1 hit.
[Graphical view ]
PROSITEi PS50835. IG_LIKE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "NTB-A, a novel SH2D1A-associated surface molecule contributing to the inability of natural killer cells to kill Epstein-Barr virus-infected B cells in X-linked Lymphoproliferative disease."
    Bottino C., Falco M., Parolini S., Marcenaro E., Augugliaro R., Sivori S., Landi E., Biassoni R., Notarangelo L.D., Moretta L., Moretta A.
    J. Exp. Med. 194:235-246(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), FUNCTION, PHOSPHORYLATION, TISSUE SPECIFICITY, INTERACTION WITH SH2D1A; PTN6 AND PTN11.
    Tissue: Lymphoid tissue.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3).
    Tissue: Spleen.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Lymph node.
  5. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
  8. "Signal peptide prediction based on analysis of experimentally verified cleavage sites."
    Zhang Z., Henzel W.J.
    Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 22-36.
  9. "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
    Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M., Schiess R., Aebersold R., Watts J.D.
    Nat. Biotechnol. 27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-171 AND ASN-178.
    Tissue: Leukemic T-cell.
  10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-274; SER-278 AND TYR-309, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  11. "NTB-A receptor crystal structure: insights into homophilic interactions in the signaling lymphocytic activation molecule receptor family."
    Cao E., Ramagopal U.A., Fedorov A., Fedorov E., Yan Q., Lary J.W., Cole J.L., Nathenson S.G., Almo S.C.
    Immunity 25:559-570(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 24-215, SUBUNIT, DISULFIDE BONDS, MUTAGENESIS OF ARG-108; GLN-110 AND SER-112.

Entry informationi

Entry nameiSLAF6_HUMAN
AccessioniPrimary (citable) accession number: Q96DU3
Secondary accession number(s): A6NMW2
, B2R8X8, Q14CF0, Q5TAS4, Q5TAS6, Q5TAT3, Q96DV0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: July 22, 2008
Last modified: September 3, 2014
This is version 118 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human cell differentiation molecules
    CD nomenclature of surface proteins of human leucocytes and list of entries
  2. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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