Reviewed,
UniProtKB/Swiss-Prot Q96DM3 (MIC1_HUMAN)
Last modified
June 16, 2009.
Version 51.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Uncharacterized protein C18orf8 Alternative name(s): Colon cancer-associated protein Mic1 Short name=Mic-1 | ||||
| Gene names |
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| Organism | Homo sapiens (Human) | ||||
| Taxonomic identifier | 9606 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Protein attributes
| Sequence length | 657 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 657 | 657 | Uncharacterized protein C18orf8 | PRO_0000096481 | |||||
Regions | |||||||||
| Domain | 471 – 637 | 167 | Mic1 | ||||||
Amino acid modifications | |||||||||
| Modified residue | 233 | 1 | Phosphothreonine Ref.4 | ||||||
| Modified residue | 234 | 1 | Phosphoserine Ref.4 | ||||||
Experimental info | |||||||||
| Sequence conflict | 163 | 1 | S → R in BAB71377. Ref.1 | ||||||
| Sequence conflict | 178 | 1 | Q → L in AAD33909. Ref.3 | ||||||
| Sequence conflict | 470 | 1 | E → DFFLYGVFKHYRQ in AAD33909. Ref.3 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.  Sugano S.Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Synovium. |
| [2] | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Lung. |
| [3] | "Identification of colon-cancer associated sequences by SSH." Linnebacher M., Meuer S.C., Rudy W. Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 35-657. Tissue: Colon carcinoma. |
| [4] | "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M. Cell 127:635-648(2006) [PubMed: 17081983] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-233 AND SER-234, MASS SPECTROMETRY. Tissue: Epithelium. |
Cross-references
Sequence databases | |
|---|---|
| AK057192 mRNA. Translation: BAB71377.1. BC002950 mRNA. Translation: AAH02950.2. BC008305 mRNA. Translation: AAH08305.2. AF143536 mRNA. Translation: AAD33909.1. Different initiation. | |
| IPI | IPI00149964. |
| RefSeq | NP_037458.3. |
| UniGene | Hs.529006 |
3D structure databases | |
| ModBase | Search... |
Proteomic databases | |
| PRIDE | Q96DM3. |
Genome annotation databases | |
| Ensembl | ENSG00000141452. Homo sapiens. [Contig view] |
| GeneID | 29919. |
| KEGG | hsa:29919. |
Organism-specific databases | |
| GeneCards | GC18P019337. |
| HGNC | HGNC:24326. C18orf8. |
| PharmGKB | PA134862561. |
| GenAtlas | Search... |
Phylogenomic databases | |
| HOGENOM | Q96DM3. |
| HOVERGEN | Q96DM3. |
| OMA | Q96DM3. IRSLNQF. |
Gene expression databases | |
| Bgee | Q96DM3. |
| CleanEx | HS_C18orf8. |
| GermOnline | ENSG00000141452. Homo sapiens. |
Family and domain databases | |
| InterPro | IPR009755. Mic1. [Graphical view] |
| Pfam | PF07035. Mic1. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 52516. |
Entry information
| Entry name | MIC1_HUMAN | ||||||||
| Accession | Primary (citable) accession number: Q96DM3 Secondary accession number(s): Q9BU17, Q9Y5M0 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HPI (Human Proteome Initiative) | ||||||||
Relevant documents
| Human chromosome 18 Human chromosome 18: entries, gene names and cross-references to MIM |
| SIMILARITY comments Index of protein domains and families |
