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Protein
Submitted name:

SMURF2 protein

Gene

SMURF2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

TransferaseSAAS annotation

Keywords - Biological processi

Ubl conjugation pathwaySAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
SMURF2 proteinImported
Gene namesi
Name:SMURF2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134985524.

PTM / Processingi

Proteomic databases

PaxDbiQ96DE7.
PeptideAtlasiQ96DE7.
PRIDEiQ96DE7.

Expressioni

Gene expression databases

BgeeiENSG00000108854.
GenevisibleiQ96DE7. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000262435.

Structurei

3D structure databases

ProteinModelPortaliQ96DE7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 288HECT (E6AP-type E3 ubiquitin-protein ligase)InterPro annotationAdd BLAST288

Phylogenomic databases

eggNOGiKOG0940. Eukaryota.
COG5021. LUCA.
HOVERGENiHBG004134.
KOiK04678.
PhylomeDBiQ96DE7.

Family and domain databases

CDDicd00078. HECTc. 1 hit.
InterProiIPR000569. HECT_dom.
[Graphical view]
PfamiPF00632. HECT. 1 hit.
[Graphical view]
SMARTiSM00119. HECTc. 1 hit.
[Graphical view]
SUPFAMiSSF56204. SSF56204. 1 hit.
PROSITEiPS50237. HECT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q96DE7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
RDDIYTLQIN PDSAVNPEHL SYFHFVGRIM GMAVFHGHYI DGGFTLPFYK
60 70 80 90 100
QLLGKSITLD DMELVDPDLH NSLVWILEND ITGVLDHTFC VEHNAYGEII
110 120 130 140 150
QHELKPNGKS IPVNEENKKE YVRLYVNWRF LRGIEAQFLA LQKGFNEVIP
160 170 180 190 200
QHLLKTFDEK ELELIICGLG KIDVNDWKVN TRLKHCTPDS NIVKWFWKAV
210 220 230 240 250
EFFDEERRAR LLQFVTGSSR VPLQGFKALQ GAAGPRLFTI HQIDACTNNL
260 270 280
PKAHTCFNRI DIPPYESYEK LYEKLLTAIE ETCGFAVE
Length:288
Mass (Da):33,255
Last modified:December 1, 2001 - v1
Checksum:iFE2B43E300E66537
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC009527 mRNA. Translation: AAH09527.1.
RefSeqiNP_073576.1. NM_022739.3.
UniGeneiHs.515011.

Genome annotation databases

GeneIDi64750.
KEGGihsa:64750.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC009527 mRNA. Translation: AAH09527.1.
RefSeqiNP_073576.1. NM_022739.3.
UniGeneiHs.515011.

3D structure databases

ProteinModelPortaliQ96DE7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000262435.

Proteomic databases

PaxDbiQ96DE7.
PeptideAtlasiQ96DE7.
PRIDEiQ96DE7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi64750.
KEGGihsa:64750.

Organism-specific databases

CTDi64750.
PharmGKBiPA134985524.

Phylogenomic databases

eggNOGiKOG0940. Eukaryota.
COG5021. LUCA.
HOVERGENiHBG004134.
KOiK04678.
PhylomeDBiQ96DE7.

Miscellaneous databases

ChiTaRSiSMURF2. human.
GenomeRNAii64750.

Gene expression databases

BgeeiENSG00000108854.
GenevisibleiQ96DE7. HS.

Family and domain databases

CDDicd00078. HECTc. 1 hit.
InterProiIPR000569. HECT_dom.
[Graphical view]
PfamiPF00632. HECT. 1 hit.
[Graphical view]
SMARTiSM00119. HECTc. 1 hit.
[Graphical view]
SUPFAMiSSF56204. SSF56204. 1 hit.
PROSITEiPS50237. HECT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ96DE7_HUMAN
AccessioniPrimary (citable) accession number: Q96DE7
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: November 30, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.