Skip Header

Contribute Send feedback
Read comments (0) or add your own

Unreviewed, UniProtKB/TrEMBL Q96D37 (Q96D37_HUMAN)

Last modified January 19, 2010. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information

Hide | Top

Names and origin

Protein namesSubmitted name:
    VAV1 protein EMBL AAH13361.2
Gene names
Name: VAV1 EMBL AAH13361.2
OrganismHomo sapiens (Human) EMBL AAH13361.2
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Hide | Top

Protein attributes

Sequence length790 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

Hide | Top

General annotation (Comments)

Sequence similarities

Contains 1 DH (DBL-homology) domain.

Contains 1 PH domain.

Contains 1 SH2 domain.

Contains 2 SH3 domains.

Hide | Top

Sequences

Sequence LengthMass (Da)Tools
Q96D37-1 [UniParc].

Last modified March 1, 2004. Version 2.
Checksum: 4A92899AAA3FDCF5

FASTA79091,991
        10         20         30         40         50         60 
MIVLPLYSRL DKRFLCLKNI RTFLSTCCEK FGLKRSELFE AFDLFDVQDF GKVIYTLSAL 

        70         80         90        100        110        120 
SWTPIAQNRG IMPFPTEEES VGDEDIYSGL SDQIDDTVEE DEDLYDCVEN EEAEGDEIYE 

       130        140        150        160        170        180 
DLMRSEPVSM PPKMTEYDKR CCCLREIQQT EEKYTDTLGS IQQHFLKPLQ RFLKPQDIEI 

       190        200        210        220        230        240 
IFINIEDLLR VHTHFLKEMK EALGTPGAAN LYQVFIKYKE RFLVYGRYCS QVESASKHLD 

       250        260        270        280        290        300 
RVAAAREDVQ MKLEECSQRA NNGRFTLRDL LMVPMQRVLK YHLLLQELVK HTQEAMEKEN 

       310        320        330        340        350        360 
LRLALDAMRD LAQCVNEVKR DNETLRQITN FQLSIENLDQ SLAHYGRPKI DGELKITSVE 

       370        380        390        400        410        420 
RRSKMDRYAF LLDKALLICK RRGDSYDLKD FVNLHSFQVR DDSSGDRDNK KWSHMFLLIE 

       430        440        450        460        470        480 
DQGAQGYELF FKTRELKKKW MEQFEMAISN IYPENATANG HDFQMFSFEE TTSCKACQML 

       490        500        510        520        530        540 
LRGTFYQGYR CHRCRASAHK ECLGRVPPCG RHGQDFPGTM KKDKLHRRAQ DKKRNELGLP 

       550        560        570        580        590        600 
KMEVFQEYYG LPPPPGAIGP FLRLNPGDIV ELTKAEAEQN WWEGRNTSTN EIGWFPCNRV 

       610        620        630        640        650        660 
KPYVHGPPQD LSVHLWYAGP MERAGAESIL ANRSDGTFLV RQRVKDAAEF AISIKYNVEV 

       670        680        690        700        710        720 
KHIKIMTAEG LYRITEKKAF RGLTELVEFY QQNSLKDCFK SLDTTLQFPF KEPEKRTISR 

       730        740        750        760        770        780 
PAVGSTKYFG TAKARYDFCA RDRSELSLKE GDIIKILNKK GQQGWWRGEI YGRVGWFPAN 

       790 
YVEEDYSEYC

« Hide

Hide | Top

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Placenta EMBL AAH13361.2.
+Additional computationally mapped references.

Hide | Top

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BC013361 mRNA. Translation: AAH13361.2.
IPIIPI00011696.
UniGeneHs.116237

3D structure databases

HSSPHSSP built from PDB template 1K1Z based on UniProtKB P27870.
SMRQ96D37. Positions 13-80, 134-510, 528-605, 574-725, 731-785.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ96D37.

Genome annotation databases

EnsemblENST00000304076; ENSP00000302269; ENSG00000141968; Homo sapiens. [Genome view]
UCSCuc002mfv.1. human.

Organism-specific databases

HGNCHGNC:12657. VAV1.
GenAtlasSearch...

Phylogenomic databases

HOVERGENQ96D37.

Gene expression databases

ArrayExpressQ96D37.
BgeeQ96D37.

Family and domain databases

InterProIPR016146. Calponin-homology.
IPR001715. Calponin_act_bd.
IPR000219. DH-domain.
IPR001331. GDS_CDC24_CS.
IPR001849. Pleckstrin_homology.
IPR002219. Prot_Kinase_C-like_PE/DAG_bd.
IPR000980. SH2.
IPR001452. SH3_domain.
IPR020473. SH3_region.
[Graphical view]
Gene3DG3DSA:1.10.418.10. Calponin-homology. 1 hit.
G3DSA:1.20.900.10. RhoGEF. 1 hit.
G3DSA:3.30.505.10. SH2. 1 hit.
PfamPF00130. C1_1. 1 hit.
PF00169. PH. 1 hit.
PF00621. RhoGEF. 1 hit.
PF00017. SH2. 1 hit.
PF00018. SH3_1. 2 hits.
[Graphical view]
PRINTSPR00401. SH2DOMAIN.
PR00452. SH3DOMAIN.
SMARTSM00109. C1. 1 hit.
SM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
SM00252. SH2. 1 hit.
SM00326. SH3. 2 hits.
[Graphical view]
PROSITEPS00741. DH_1. 1 hit.
PS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS50001. SH2. 1 hit.
PS50002. SH3. 2 hits.
PS00479. ZF_DAG_PE_1. 1 hit.
PS50081. ZF_DAG_PE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Hide | Top

Entry information

Entry nameQ96D37_HUMAN
AccessionPrimary (citable) accession number: Q96D37
Entry history
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: March 1, 2004
Last modified: January 19, 2010
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information