Q96CP2 (FWCH2_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
FLYWCH family member 2

Gene names

Name:

FLYWCH2

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	140 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 140	140	FLYWCH family member 2		PRO_0000316523
Amino acid modifications
	Modified residue	21	1	Phosphoserine Ref.3 Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Q96CP2 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 588F2C07C51B9A77	FASTA	140	14,564
	10 20 30 40 50 60 MPLPEPSEQE GESVKASQEP SPKPGTEVIP AAPRKPRKFS KLVLLTASKD STKVAGAKRK 70 80 90 100 110 120 GVHCVMSLGV PGPATLAKAL LQTHPEAQRA IEAAPQEPEQ KRSRQDPGTD RTEDSGLAAG 130 140 PPEAAGENFA PCSVAPGKSL

References

[1]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Uterus.
[3]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[4]	"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis." Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M. Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[5]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH471112 Genomic DNA. Translation: EAW85455.1. BC014089 mRNA. Translation: AAH14089.1.
IPI	IPI00060521.
RefSeq	NP_001135971.1. NM_001142499.1. NP_001135972.1. NM_001142500.1. NP_612448.1. NM_138439.2.
UniGene	Hs.534525.
3D structure databases
ProteinModelPortal	Q96CP2.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000293981.
PTM databases
PhosphoSite	Q96CP2.
Proteomic databases
PaxDb	Q96CP2.
PeptideAtlas	Q96CP2.
PRIDE	Q96CP2.
Protocols and materials databases
DNASU	114984.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000293981; ENSP00000293981; ENSG00000162076. ENST00000396958; ENSP00000380159; ENSG00000162076.
GeneID	114984.
KEGG	hsa:114984.
UCSC	uc002csa.3. human.
Organism-specific databases
CTD	114984.
GeneCards	GC16P002934.
H-InvDB	HIX0012743.
HGNC	HGNC:25178. FLYWCH2.
HPA	HPA041354.
neXtProt	NX_Q96CP2.
PharmGKB	PA162388745.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG45173.
HOGENOM	HOG000112674.
HOVERGEN	HBG097174.
InParanoid	Q96CP2.
OMA	ENSAPCS.
OrthoDB	EOG4RXZ1J.
PhylomeDB	Q96CP2.
Gene expression databases
ArrayExpress	Q96CP2.
Bgee	Q96CP2.
CleanEx	HS_FLYWCH2.
Genevestigator	Q96CP2.
Family and domain databases
ProtoNet	Search...
Other
GenomeRNAi	114984.
NextBio	79468.

Entry information

Entry name

FWCH2_HUMAN

Accession

Primary (citable) accession number: Q96CP2

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	December 1, 2001
Last modified:	April 3, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.