Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

FLYWCH family member 2

Gene

FLYWCH2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. poly(A) RNA binding Source: UniProtKB
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
FLYWCH family member 2
Gene namesi
Name:FLYWCH2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 16

Organism-specific databases

HGNCiHGNC:25178. FLYWCH2.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162388745.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 140140FLYWCH family member 2PRO_0000316523Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei21 – 211Phosphoserine2 Publications

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ96CP2.
PaxDbiQ96CP2.
PeptideAtlasiQ96CP2.
PRIDEiQ96CP2.

PTM databases

PhosphoSiteiQ96CP2.

Expressioni

Gene expression databases

BgeeiQ96CP2.
CleanExiHS_FLYWCH2.
ExpressionAtlasiQ96CP2. baseline and differential.
GenevestigatoriQ96CP2.

Organism-specific databases

HPAiHPA041354.

Interactioni

Protein-protein interaction databases

BioGridi125404. 14 interactions.
IntActiQ96CP2. 1 interaction.
STRINGi9606.ENSP00000293981.

Structurei

3D structure databases

ProteinModelPortaliQ96CP2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG45173.
GeneTreeiENSGT00530000064166.
HOGENOMiHOG000112674.
HOVERGENiHBG097174.
InParanoidiQ96CP2.
OMAiAGENFAP.
OrthoDBiEOG7JT6VK.
PhylomeDBiQ96CP2.
TreeFamiTF338211.

Family and domain databases

InterProiIPR029279. FLYWCH_N.
[Graphical view]
PfamiPF15423. FLYWCH_N. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q96CP2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLPEPSEQE GESVKASQEP SPKPGTEVIP AAPRKPRKFS KLVLLTASKD
60 70 80 90 100
STKVAGAKRK GVHCVMSLGV PGPATLAKAL LQTHPEAQRA IEAAPQEPEQ
110 120 130 140
KRSRQDPGTD RTEDSGLAAG PPEAAGENFA PCSVAPGKSL
Length:140
Mass (Da):14,564
Last modified:December 1, 2001 - v1
Checksum:i588F2C07C51B9A77
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471112 Genomic DNA. Translation: EAW85455.1.
BC014089 mRNA. Translation: AAH14089.1.
CCDSiCCDS10482.1.
RefSeqiNP_001135971.1. NM_001142499.1.
NP_001135972.1. NM_001142500.1.
NP_612448.1. NM_138439.2.
XP_005255135.1. XM_005255078.2.
UniGeneiHs.534525.

Genome annotation databases

EnsembliENST00000293981; ENSP00000293981; ENSG00000162076.
ENST00000396958; ENSP00000380159; ENSG00000162076.
GeneIDi114984.
KEGGihsa:114984.
UCSCiuc002csa.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471112 Genomic DNA. Translation: EAW85455.1.
BC014089 mRNA. Translation: AAH14089.1.
CCDSiCCDS10482.1.
RefSeqiNP_001135971.1. NM_001142499.1.
NP_001135972.1. NM_001142500.1.
NP_612448.1. NM_138439.2.
XP_005255135.1. XM_005255078.2.
UniGeneiHs.534525.

3D structure databases

ProteinModelPortaliQ96CP2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi125404. 14 interactions.
IntActiQ96CP2. 1 interaction.
STRINGi9606.ENSP00000293981.

PTM databases

PhosphoSiteiQ96CP2.

Proteomic databases

MaxQBiQ96CP2.
PaxDbiQ96CP2.
PeptideAtlasiQ96CP2.
PRIDEiQ96CP2.

Protocols and materials databases

DNASUi114984.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000293981; ENSP00000293981; ENSG00000162076.
ENST00000396958; ENSP00000380159; ENSG00000162076.
GeneIDi114984.
KEGGihsa:114984.
UCSCiuc002csa.3. human.

Organism-specific databases

CTDi114984.
GeneCardsiGC16P002934.
H-InvDBHIX0012743.
HGNCiHGNC:25178. FLYWCH2.
HPAiHPA041354.
neXtProtiNX_Q96CP2.
PharmGKBiPA162388745.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG45173.
GeneTreeiENSGT00530000064166.
HOGENOMiHOG000112674.
HOVERGENiHBG097174.
InParanoidiQ96CP2.
OMAiAGENFAP.
OrthoDBiEOG7JT6VK.
PhylomeDBiQ96CP2.
TreeFamiTF338211.

Miscellaneous databases

GenomeRNAii114984.
NextBioi79468.
PROiQ96CP2.

Gene expression databases

BgeeiQ96CP2.
CleanExiHS_FLYWCH2.
ExpressionAtlasiQ96CP2. baseline and differential.
GenevestigatoriQ96CP2.

Family and domain databases

InterProiIPR029279. FLYWCH_N.
[Graphical view]
PfamiPF15423. FLYWCH_N. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Uterus.
  3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  4. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  5. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiFWCH2_HUMAN
AccessioniPrimary (citable) accession number: Q96CP2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: December 1, 2001
Last modified: January 7, 2015
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.