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Q96CP2 (FWCH2_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
FLYWCH family member 2
Gene names
Name:FLYWCH2
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length140 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Ontologies

Keywords
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionpoly(A) RNA binding

Inferred from direct assay PubMed 22658674. Source: UniProtKB

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 140140FLYWCH family member 2
PRO_0000316523

Amino acid modifications

Modified residue211Phosphoserine Ref.3 Ref.4

Sequences

Sequence LengthMass (Da)Tools
Q96CP2 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 588F2C07C51B9A77

FASTA14014,564
        10         20         30         40         50         60 
MPLPEPSEQE GESVKASQEP SPKPGTEVIP AAPRKPRKFS KLVLLTASKD STKVAGAKRK 

        70         80         90        100        110        120 
GVHCVMSLGV PGPATLAKAL LQTHPEAQRA IEAAPQEPEQ KRSRQDPGTD RTEDSGLAAG 

       130        140 
PPEAAGENFA PCSVAPGKSL 

« Hide

References

[1]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Uterus.
[3]"A quantitative atlas of mitotic phosphorylation."
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[4]"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[5]"Initial characterization of the human central proteome."
Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH471112 Genomic DNA. Translation: EAW85455.1.
BC014089 mRNA. Translation: AAH14089.1.
CCDSCCDS10482.1.
RefSeqNP_001135971.1. NM_001142499.1.
NP_001135972.1. NM_001142500.1.
NP_612448.1. NM_138439.2.
XP_005255135.1. XM_005255078.2.
UniGeneHs.534525.

3D structure databases

ProteinModelPortalQ96CP2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid125404. 3 interactions.
STRING9606.ENSP00000293981.

PTM databases

PhosphoSiteQ96CP2.

Proteomic databases

MaxQBQ96CP2.
PaxDbQ96CP2.
PeptideAtlasQ96CP2.
PRIDEQ96CP2.

Protocols and materials databases

DNASU114984.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000293981; ENSP00000293981; ENSG00000162076.
ENST00000396958; ENSP00000380159; ENSG00000162076.
GeneID114984.
KEGGhsa:114984.
UCSCuc002csa.3. human.

Organism-specific databases

CTD114984.
GeneCardsGC16P002934.
H-InvDBHIX0012743.
HGNCHGNC:25178. FLYWCH2.
HPAHPA041354.
neXtProtNX_Q96CP2.
PharmGKBPA162388745.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG45173.
HOGENOMHOG000112674.
HOVERGENHBG097174.
InParanoidQ96CP2.
OMAAGENFAP.
OrthoDBEOG7JT6VK.
PhylomeDBQ96CP2.
TreeFamTF338211.

Gene expression databases

ArrayExpressQ96CP2.
BgeeQ96CP2.
CleanExHS_FLYWCH2.
GenevestigatorQ96CP2.

Family and domain databases

InterProIPR029279. FLYWCH_N.
[Graphical view]
PfamPF15423. FLYWCH_N. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi114984.
NextBio79468.
PROQ96CP2.

Entry information

Entry nameFWCH2_HUMAN
AccessionPrimary (citable) accession number: Q96CP2
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: December 1, 2001
Last modified: July 9, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 16

Human chromosome 16: entries, gene names and cross-references to MIM