Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q96CP2

- FWCH2_HUMAN

UniProt

Q96CP2 - FWCH2_HUMAN

Protein

FLYWCH family member 2

Gene

FLYWCH2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. poly(A) RNA binding Source: UniProtKB

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    FLYWCH family member 2
    Gene namesi
    Name:FLYWCH2
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 16

    Organism-specific databases

    HGNCiHGNC:25178. FLYWCH2.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA162388745.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 140140FLYWCH family member 2PRO_0000316523Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei21 – 211Phosphoserine2 Publications

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiQ96CP2.
    PaxDbiQ96CP2.
    PeptideAtlasiQ96CP2.
    PRIDEiQ96CP2.

    PTM databases

    PhosphoSiteiQ96CP2.

    Expressioni

    Gene expression databases

    ArrayExpressiQ96CP2.
    BgeeiQ96CP2.
    CleanExiHS_FLYWCH2.
    GenevestigatoriQ96CP2.

    Organism-specific databases

    HPAiHPA041354.

    Interactioni

    Protein-protein interaction databases

    BioGridi125404. 3 interactions.
    IntActiQ96CP2. 1 interaction.
    STRINGi9606.ENSP00000293981.

    Structurei

    3D structure databases

    ProteinModelPortaliQ96CP2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG45173.
    HOGENOMiHOG000112674.
    HOVERGENiHBG097174.
    InParanoidiQ96CP2.
    OMAiAGENFAP.
    OrthoDBiEOG7JT6VK.
    PhylomeDBiQ96CP2.
    TreeFamiTF338211.

    Family and domain databases

    InterProiIPR029279. FLYWCH_N.
    [Graphical view]
    PfamiPF15423. FLYWCH_N. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q96CP2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPLPEPSEQE GESVKASQEP SPKPGTEVIP AAPRKPRKFS KLVLLTASKD    50
    STKVAGAKRK GVHCVMSLGV PGPATLAKAL LQTHPEAQRA IEAAPQEPEQ 100
    KRSRQDPGTD RTEDSGLAAG PPEAAGENFA PCSVAPGKSL 140
    Length:140
    Mass (Da):14,564
    Last modified:December 1, 2001 - v1
    Checksum:i588F2C07C51B9A77
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH471112 Genomic DNA. Translation: EAW85455.1.
    BC014089 mRNA. Translation: AAH14089.1.
    CCDSiCCDS10482.1.
    RefSeqiNP_001135971.1. NM_001142499.1.
    NP_001135972.1. NM_001142500.1.
    NP_612448.1. NM_138439.2.
    XP_005255135.1. XM_005255078.2.
    UniGeneiHs.534525.

    Genome annotation databases

    EnsembliENST00000293981; ENSP00000293981; ENSG00000162076.
    ENST00000396958; ENSP00000380159; ENSG00000162076.
    GeneIDi114984.
    KEGGihsa:114984.
    UCSCiuc002csa.3. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH471112 Genomic DNA. Translation: EAW85455.1 .
    BC014089 mRNA. Translation: AAH14089.1 .
    CCDSi CCDS10482.1.
    RefSeqi NP_001135971.1. NM_001142499.1.
    NP_001135972.1. NM_001142500.1.
    NP_612448.1. NM_138439.2.
    XP_005255135.1. XM_005255078.2.
    UniGenei Hs.534525.

    3D structure databases

    ProteinModelPortali Q96CP2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 125404. 3 interactions.
    IntActi Q96CP2. 1 interaction.
    STRINGi 9606.ENSP00000293981.

    PTM databases

    PhosphoSitei Q96CP2.

    Proteomic databases

    MaxQBi Q96CP2.
    PaxDbi Q96CP2.
    PeptideAtlasi Q96CP2.
    PRIDEi Q96CP2.

    Protocols and materials databases

    DNASUi 114984.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000293981 ; ENSP00000293981 ; ENSG00000162076 .
    ENST00000396958 ; ENSP00000380159 ; ENSG00000162076 .
    GeneIDi 114984.
    KEGGi hsa:114984.
    UCSCi uc002csa.3. human.

    Organism-specific databases

    CTDi 114984.
    GeneCardsi GC16P002934.
    H-InvDB HIX0012743.
    HGNCi HGNC:25178. FLYWCH2.
    HPAi HPA041354.
    neXtProti NX_Q96CP2.
    PharmGKBi PA162388745.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG45173.
    HOGENOMi HOG000112674.
    HOVERGENi HBG097174.
    InParanoidi Q96CP2.
    OMAi AGENFAP.
    OrthoDBi EOG7JT6VK.
    PhylomeDBi Q96CP2.
    TreeFami TF338211.

    Miscellaneous databases

    GenomeRNAii 114984.
    NextBioi 79468.
    PROi Q96CP2.

    Gene expression databases

    ArrayExpressi Q96CP2.
    Bgeei Q96CP2.
    CleanExi HS_FLYWCH2.
    Genevestigatori Q96CP2.

    Family and domain databases

    InterProi IPR029279. FLYWCH_N.
    [Graphical view ]
    Pfami PF15423. FLYWCH_N. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Uterus.
    3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    4. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    5. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiFWCH2_HUMAN
    AccessioniPrimary (citable) accession number: Q96CP2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 5, 2008
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 16
      Human chromosome 16: entries, gene names and cross-references to MIM

    External Data

    Dasty 3