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Protein
Submitted name:

FHL3 protein

Gene

FHL3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
FHL3 proteinImported
Gene namesi
Name:FHL3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiQ96C98.
PeptideAtlasiQ96C98.
PRIDEiQ96C98.

Expressioni

Gene expression databases

BgeeiENSG00000183386.
GenevisibleiQ96C98. HS.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
FAM90A1Q86YD73EBI-10229248,EBI-6658203
PLEKHF2Q9H8W43EBI-10229248,EBI-742388
PPIGQ134273EBI-10229248,EBI-396072
TRAF3IP2O437343EBI-10229248,EBI-744798
TRIM27P143733EBI-10229248,EBI-719493
UBE2IQ7KZS03EBI-10229248,EBI-10180829

Protein-protein interaction databases

IntActiQ96C98. 6 interactions.
STRINGi9606.ENSP00000362107.

Structurei

3D structure databases

ProteinModelPortaliQ96C98.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 5151LIM zinc-bindingInterPro annotationAdd
BLAST
Domaini52 – 11160LIM zinc-bindingInterPro annotationAdd
BLAST
Domaini112 – 17261LIM zinc-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 3 LIM zinc-binding domains.UniRule annotation

Keywords - Domaini

LIM domainUniRule annotation

Phylogenomic databases

eggNOGiKOG1704. Eukaryota.
ENOG410XP0W. LUCA.
HOVERGENiHBG074526.

Family and domain databases

Gene3Di2.10.110.10. 3 hits.
InterProiIPR001781. Znf_LIM.
[Graphical view]
PfamiPF00412. LIM. 3 hits.
[Graphical view]
SMARTiSM00132. LIM. 3 hits.
[Graphical view]
PROSITEiPS00478. LIM_DOMAIN_1. 2 hits.
PS50023. LIM_DOMAIN_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q96C98-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGSRKLEYG GQTWHEHCFL CSGCEQPLGS RSFVPDKGAH YCVPCYENKF
60 70 80 90 100
APRCARCSKT LTQGGVTYRD QPWHRECLVC TGCQTPLAGQ QFTSRDEDPY
110 120 130 140 150
CVACFGELFA PKCSSCKRPI VGLGGGKYVS FEDRHWHHNC FSCARCSTSL
160 170
VGQGFVPDGD QVLCQGCSQA GP
Length:172
Mass (Da):18,918
Last modified:December 1, 2001 - v1
Checksum:i5918FF5E8C015BE6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC014501 mRNA. Translation: AAH14501.1.
RefSeqiNP_001230807.1. NM_001243878.1.
UniGeneiHs.57687.

Genome annotation databases

GeneIDi2275.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC014501 mRNA. Translation: AAH14501.1.
RefSeqiNP_001230807.1. NM_001243878.1.
UniGeneiHs.57687.

3D structure databases

ProteinModelPortaliQ96C98.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ96C98. 6 interactions.
STRINGi9606.ENSP00000362107.

Proteomic databases

PaxDbiQ96C98.
PeptideAtlasiQ96C98.
PRIDEiQ96C98.

Protocols and materials databases

DNASUi2275.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2275.

Organism-specific databases

CTDi2275.

Phylogenomic databases

eggNOGiKOG1704. Eukaryota.
ENOG410XP0W. LUCA.
HOVERGENiHBG074526.

Miscellaneous databases

ChiTaRSiFHL3. human.
GenomeRNAii2275.

Gene expression databases

BgeeiENSG00000183386.
GenevisibleiQ96C98. HS.

Family and domain databases

Gene3Di2.10.110.10. 3 hits.
InterProiIPR001781. Znf_LIM.
[Graphical view]
PfamiPF00412. LIM. 3 hits.
[Graphical view]
SMARTiSM00132. LIM. 3 hits.
[Graphical view]
PROSITEiPS00478. LIM_DOMAIN_1. 2 hits.
PS50023. LIM_DOMAIN_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ96C98_HUMAN
AccessioniPrimary (citable) accession number: Q96C98
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: September 7, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.