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Protein

Ankyrin repeat domain-containing protein 9

Gene

ANKRD9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

BioCyciZFISH:ENSG00000156381-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ankyrin repeat domain-containing protein 9
Gene namesi
Name:ANKRD9
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

HGNCiHGNC:20096. ANKRD9.

Pathology & Biotechi

Organism-specific databases

DisGeNETi122416.
OpenTargetsiENSG00000156381.
PharmGKBiPA134971966.

Polymorphism and mutation databases

BioMutaiANKRD9.
DMDMi34582329.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000669031 – 317Ankyrin repeat domain-containing protein 9Add BLAST317

Proteomic databases

EPDiQ96BM1.
PaxDbiQ96BM1.
PeptideAtlasiQ96BM1.
PRIDEiQ96BM1.

PTM databases

iPTMnetiQ96BM1.
PhosphoSitePlusiQ96BM1.

Expressioni

Gene expression databases

BgeeiENSG00000156381.
CleanExiHS_ANKRD9.
ExpressionAtlasiQ96BM1. baseline and differential.
GenevisibleiQ96BM1. HS.

Organism-specific databases

HPAiHPA055985.

Interactioni

Protein-protein interaction databases

BioGridi125768. 2 interactors.
STRINGi9606.ENSP00000286918.

Structurei

3D structure databases

ProteinModelPortaliQ96BM1.
SMRiQ96BM1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati71 – 100ANK 1Add BLAST30
Repeati112 – 141ANK 2Add BLAST30
Repeati158 – 187ANK 3Add BLAST30

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi229 – 237Poly-Leu9

Sequence similaritiesi

Contains 3 ANK repeats.PROSITE-ProRule annotation

Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

eggNOGiKOG0504. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00390000018116.
HOGENOMiHOG000013128.
HOVERGENiHBG050505.
InParanoidiQ96BM1.
OMAiSAGFRCC.
OrthoDBiEOG091G0DYT.
PhylomeDBiQ96BM1.
TreeFamiTF331214.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q96BM1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPWDARRPGG GADGGPEASG AARSRAQKQC RKSSFAFYQA VRDLLPVWLL
60 70 80 90 100
EDMRASEAFH WDERGRAAAY SPSEALLYAL VHDHQAYAHY LLATFPRRAL
110 120 130 140 150
APPSAGFRCC AAPGPHVALA VRYNRVGILR RILRTLRDFP AEERARVLDR
160 170 180 190 200
RGCSRVEGGG TSLHVACELA RPECLFLLLG HGASPGLRDG GGLTPLELLL
210 220 230 240 250
RQLGRDAGAT PSAAGAPASA PGEPRQRRLL LLDLLALYTP VGAAGSARQE
260 270 280 290 300
LLGDRPRWQR LLGEDKFQWL AGLAPPSLFA RAMQVLVTAI SPGRFPEALD
310
ELPLPPFLQP LDLTGKG
Length:317
Mass (Da):34,295
Last modified:December 1, 2001 - v1
Checksum:i9667F8A9437BC790
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX161460 mRNA. Translation: CAD61921.1.
AK291868 mRNA. Translation: BAF84557.1.
AL136293 Genomic DNA. No translation available.
CH471061 Genomic DNA. Translation: EAW81792.1.
BC015422 mRNA. Translation: AAH15422.1.
BC027479 mRNA. Translation: AAH27479.1.
CCDSiCCDS9973.1.
RefSeqiNP_689539.1. NM_152326.2.
XP_005267367.1. XM_005267310.2.
XP_005267368.1. XM_005267311.3.
UniGeneiHs.432945.

Genome annotation databases

EnsembliENST00000286918; ENSP00000286918; ENSG00000156381.
ENST00000559651; ENSP00000454100; ENSG00000156381.
ENST00000560748; ENSP00000453650; ENSG00000156381.
GeneIDi122416.
KEGGihsa:122416.
UCSCiuc001ylx.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX161460 mRNA. Translation: CAD61921.1.
AK291868 mRNA. Translation: BAF84557.1.
AL136293 Genomic DNA. No translation available.
CH471061 Genomic DNA. Translation: EAW81792.1.
BC015422 mRNA. Translation: AAH15422.1.
BC027479 mRNA. Translation: AAH27479.1.
CCDSiCCDS9973.1.
RefSeqiNP_689539.1. NM_152326.2.
XP_005267367.1. XM_005267310.2.
XP_005267368.1. XM_005267311.3.
UniGeneiHs.432945.

3D structure databases

ProteinModelPortaliQ96BM1.
SMRiQ96BM1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi125768. 2 interactors.
STRINGi9606.ENSP00000286918.

PTM databases

iPTMnetiQ96BM1.
PhosphoSitePlusiQ96BM1.

Polymorphism and mutation databases

BioMutaiANKRD9.
DMDMi34582329.

Proteomic databases

EPDiQ96BM1.
PaxDbiQ96BM1.
PeptideAtlasiQ96BM1.
PRIDEiQ96BM1.

Protocols and materials databases

DNASUi122416.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000286918; ENSP00000286918; ENSG00000156381.
ENST00000559651; ENSP00000454100; ENSG00000156381.
ENST00000560748; ENSP00000453650; ENSG00000156381.
GeneIDi122416.
KEGGihsa:122416.
UCSCiuc001ylx.2. human.

Organism-specific databases

CTDi122416.
DisGeNETi122416.
GeneCardsiANKRD9.
HGNCiHGNC:20096. ANKRD9.
HPAiHPA055985.
neXtProtiNX_Q96BM1.
OpenTargetsiENSG00000156381.
PharmGKBiPA134971966.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0504. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00390000018116.
HOGENOMiHOG000013128.
HOVERGENiHBG050505.
InParanoidiQ96BM1.
OMAiSAGFRCC.
OrthoDBiEOG091G0DYT.
PhylomeDBiQ96BM1.
TreeFamiTF331214.

Enzyme and pathway databases

BioCyciZFISH:ENSG00000156381-MONOMER.

Miscellaneous databases

GenomeRNAii122416.
PROiQ96BM1.

Gene expression databases

BgeeiENSG00000156381.
CleanExiHS_ANKRD9.
ExpressionAtlasiQ96BM1. baseline and differential.
GenevisibleiQ96BM1. HS.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiANKR9_HUMAN
AccessioniPrimary (citable) accession number: Q96BM1
Secondary accession number(s): A8K753
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 9, 2003
Last sequence update: December 1, 2001
Last modified: November 2, 2016
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.