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Protein
Submitted name:

ACTN4 protein

Gene

ACTN4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
ACTN4 proteinImported
Gene namesi
Name:ACTN4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiQ96BG6.
PeptideAtlasiQ96BG6.
PRIDEiQ96BG6.

Expressioni

Gene expression databases

BgeeiENSG00000130402.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000252699.

Structurei

3D structure databases

ProteinModelPortaliQ96BG6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini488 – 52336EF-handInterPro annotationAdd
BLAST
Domaini529 – 56436EF-handInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili172 – 20635Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0035. Eukaryota.
COG5069. LUCA.
HOVERGENiHBG050453.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR029637. ACTN4.
IPR011992. EF-hand-dom_pair.
IPR014837. EF-hand_Ca_insen.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR018159. Spectrin/alpha-actinin.
IPR002017. Spectrin_repeat.
[Graphical view]
PANTHERiPTHR11915:SF271. PTHR11915:SF271. 1 hit.
PfamiPF08726. EFhand_Ca_insen. 1 hit.
PF00435. Spectrin. 4 hits.
[Graphical view]
SMARTiSM00054. EFh. 2 hits.
SM00150. SPEC. 4 hits.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiPS00018. EF_HAND_1. 1 hit.
PS50222. EF_HAND_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q96BG6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ANRICKVLAV NQENEHLMED YEKLASDLLE WIRRTIPWLE DRVPQKTIQE
60 70 80 90 100
MQQKLEDFRD YRRVHKPPKV QEKCQLEINF NTLQTKLRLS NRPAFMPSEG
110 120 130 140 150
KMVSDINNGW QHLEQAEKGY EEWLLNEIRR LERLDHLAEK FRQKASIHEA
160 170 180 190 200
WTDGKEAMLK HRDYETATLS DIKALIRKHE AFESDLAAHQ DRVEQIAAIA
210 220 230 240 250
QELNELDYYD SHNVNTRCQK ICDQWDALGS LTHSRREALE KTEKQLEAID
260 270 280 290 300
QLHLEYAKRA APFNNWMESA MEDLQDMFIV HTIEEIEGLI SAHDQFKSTL
310 320 330 340 350
PDADREREAI LAIHKEAQRI AESNHIKLSG SNPYTTVTPQ IINSKWEKVQ
360 370 380 390 400
QLVPKRDHAL LEEQSKQQSN EHLRRQFASQ ANVVGPWIQT KMEEIGRISI
410 420 430 440 450
EMNGTLEDQL SHLKQYERSI VDYKPNLDLL EQQHQLIQEA LIFDNKHTNY
460 470 480 490 500
TMEHIRVGWE QLLTTIARTI NEVENQILTR DAKGISQEQM QEFRASFNHF
510 520 530 540 550
DKDHGGALGP EEFKACLISL GYDVENDRQG EAEFNRIMSL VDPNHSGLVT
560 570 580 590 600
FQAFIDFMSR ETTDTDTADQ VIASFKVLAG DKNFITAEEL RRELPPDQAE
610 620 630
YCIARMAPYQ GPDAVPGALD YKSFSTALYG ESDL
Length:634
Mass (Da):73,620
Last modified:March 1, 2004 - v2
Checksum:i1A44454EA308BE36
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC015620 mRNA. Translation: AAH15620.2.
UniGeneiHs.270291.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC015620 mRNA. Translation: AAH15620.2.
UniGeneiHs.270291.

3D structure databases

ProteinModelPortaliQ96BG6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000252699.

Proteomic databases

PaxDbiQ96BG6.
PeptideAtlasiQ96BG6.
PRIDEiQ96BG6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0035. Eukaryota.
COG5069. LUCA.
HOVERGENiHBG050453.

Miscellaneous databases

ChiTaRSiACTN4. human.

Gene expression databases

BgeeiENSG00000130402.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR029637. ACTN4.
IPR011992. EF-hand-dom_pair.
IPR014837. EF-hand_Ca_insen.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR018159. Spectrin/alpha-actinin.
IPR002017. Spectrin_repeat.
[Graphical view]
PANTHERiPTHR11915:SF271. PTHR11915:SF271. 1 hit.
PfamiPF08726. EFhand_Ca_insen. 1 hit.
PF00435. Spectrin. 4 hits.
[Graphical view]
SMARTiSM00054. EFh. 2 hits.
SM00150. SPEC. 4 hits.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiPS00018. EF_HAND_1. 1 hit.
PS50222. EF_HAND_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ96BG6_HUMAN
AccessioniPrimary (citable) accession number: Q96BG6
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: March 1, 2004
Last modified: September 7, 2016
This is version 93 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.