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Protein

Leukocyte receptor cluster member 9

Gene

LENG9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri40 – 67C3H1-typePROSITE-ProRule annotationAdd BLAST28

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Leukocyte receptor cluster member 9
Gene namesi
Name:LENG9
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

HGNCiHGNC:16306. LENG9.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134975056.

Polymorphism and mutation databases

BioMutaiLENG9.
DMDMi296434565.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002636881 – 501Leukocyte receptor cluster member 9Add BLAST501

Proteomic databases

EPDiQ96B70.
MaxQBiQ96B70.
PaxDbiQ96B70.
PeptideAtlasiQ96B70.
PRIDEiQ96B70.

PTM databases

iPTMnetiQ96B70.
PhosphoSitePlusiQ96B70.

Expressioni

Gene expression databases

CleanExiHS_LENG9.

Organism-specific databases

HPAiHPA051671.
HPA053556.

Interactioni

Protein-protein interaction databases

BioGridi125106. 3 interactors.
IntActiQ96B70. 2 interactors.
MINTiMINT-7944902.
STRINGi9606.ENSP00000331647.

Structurei

3D structure databases

ProteinModelPortaliQ96B70.
SMRiQ96B70.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri40 – 67C3H1-typePROSITE-ProRule annotationAdd BLAST28

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG410IWVT. Eukaryota.
ENOG4111GEQ. LUCA.
HOGENOMiHOG000062983.
HOVERGENiHBG068924.
InParanoidiQ96B70.
OrthoDBiEOG091G07VD.
PhylomeDBiQ96B70.
TreeFamiTF329287.

Family and domain databases

Gene3Di3.90.1140.10. 1 hit.
4.10.1000.10. 1 hit.
InterProiView protein in InterPro
IPR009097. cNuc_Pdiesterase.
IPR019510. Kinase-A_anchor_nucl_local_sig.
IPR007547. UPF0248.
IPR000571. Znf_CCCH.
IPR036855. Znf_CCCH_sf.
PfamiView protein in Pfam
PF10469. AKAP7_NLS. 1 hit.
PF04457. DUF504. 1 hit.
SMARTiView protein in SMART
SM00356. ZnF_C3H1. 1 hit.
SUPFAMiSSF55144. SSF55144. 1 hit.
PROSITEiView protein in PROSITE
PS50103. ZF_C3H1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q96B70-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSRPPCGAT SSARRACQFP APMAAAREPE LPQEAPATEP APPPACRFFL
60 70 80 90 100
EGRCRFGARC RQPHPGAPAP PGREAQPEAG AKKPPLRTAA DVIQRIRWDP
110 120 130 140 150
RLDPADFSVG YVDRFLGVRE EPFSAFCWDQ PLAALGPGVL AVPQHRVRFF
160 170 180 190 200
RFHGRLVWDR ASRTDLVFGS GSAAGRGPTI LDAPNTEGAH GAEGAEWTLA
210 220 230 240 250
GTGQEAQAAP KRGSTRPLCT GHQEPGVEEP GELEAAQERA LGTAADLGTL
260 270 280 290 300
APRGRLAGVT EEALKPTAAT RTTLLGGKEA QALGVPGGSA ETTEAEWGPA
310 320 330 340 350
AWPEDKRARL SVAAPCQPRP THFVALMVTE PGLQAEVTKA QEYLVHVAPH
360 370 380 390 400
CANFLVPSQN LHLTLALLRL AGAGEEAAAI GALRRALLAP GLNAPPRLSF
410 420 430 440 450
RKLVLLGPHV LCAPPSPTLE SMAQVLSQRL EAEGLSTLQS PGQLHPHLTV
460 470 480 490 500
AKVPHGSQVH LPKLEFTLSQ EVGCQPLQTL WLCRIGRTGG PFQPLAEIRL

E
Length:501
Mass (Da):53,167
Last modified:May 18, 2010 - v2
Checksum:i6AF04904A6518554
GO

Sequence cautioni

The sequence AAH15921 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_029602153H → R. Corresponds to variant dbSNP:rs10406453Ensembl.1
Natural variantiVAR_029603499R → P. Corresponds to variant dbSNP:rs10423424Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008746 Genomic DNA. No translation available.
CU207370 Genomic DNA. No translation available.
CH471135 Genomic DNA. Translation: EAW72251.1.
BC015921 mRNA. Translation: AAH15921.1. Different initiation.
RefSeqiNP_945339.2. NM_198988.1.
UniGeneiHs.590976.

Genome annotation databases

EnsembliENST00000614111; ENSP00000483600; ENSG00000274495.
ENST00000622419; ENSP00000477636; ENSG00000273574.
GeneIDi94059.
KEGGihsa:94059.
UCSCiuc032jrx.2. human.

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiLENG9_HUMAN
AccessioniPrimary (citable) accession number: Q96B70
Secondary accession number(s): B2VAM3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: May 18, 2010
Last modified: October 25, 2017
This is version 113 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

It is uncertain whether Met-1 or Met-23 is the initiator.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations