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Protein
Submitted name:

USP25 protein

Gene

USP25

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
USP25 proteinImported
Submitted name:
Ubiquitin carboxyl-terminal hydrolase 25Imported
Gene namesi
Name:USP25Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 21

Organism-specific databases

EuPathDBiHostDB:ENSG00000155313.15
HGNCiHGNC:12624 USP25

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000155313

Expressioni

Gene expression databases

BgeeiENSG00000155313

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini169 – 450USPInterPro annotationAdd BLAST282

Sequence similaritiesi

Belongs to the peptidase C19 family.SAAS annotation

Phylogenomic databases

eggNOGiKOG1863 Eukaryota
COG5077 LUCA
GeneTreeiENSGT00390000016082
HOGENOMiHOG000151245

Family and domain databases

InterProiView protein in InterPro
IPR001394 Peptidase_C19_UCH
IPR009060 UBA-like_sf
IPR003903 UIM_dom
IPR018200 USP_CS
IPR028889 USP_dom
PfamiView protein in Pfam
PF00443 UCH, 1 hit
PF02809 UIM, 2 hits
SMARTiView protein in SMART
SM00726 UIM, 1 hit
SUPFAMiSSF46934 SSF46934, 1 hit
PROSITEiView protein in PROSITE
PS50330 UIM, 1 hit
PS00972 USP_1, 1 hit
PS50235 USP_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q96B65-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVEQNVLQQ SAAQKHQQTF LNQLREITGI NDTQILQQAL KDSNGNLELA
60 70 80 90 100
VAFLTAKNAK TPQQEETTYY QTALPGNDRY ISVGSQADTN VIDLTGDDKD
110 120 130 140 150
DLQRAIALSL AESNRAFRET GITDEEQAIS RVLEASIAEN KACLKRTPTE
160 170 180 190 200
VWRDSRNPYD RKRQDKAPVG LKNVGNTCWF SAVIQSLFNL LEFRRLVLNY
210 220 230 240 250
KPPSNAQDLP RNQKEHRNLP FMRELRYLFA LLVGTKRKYV DPSRAVEILK
260 270 280 290 300
DAFKSNDSQQ EWHQDYRKFR ETTMYLIIGL ENFQRESYID SLLFLICAYQ
310 320 330 340 350
NNKELLSKGL YRGHDEELIS HYRRECLLKL NEQAAELFES GEDREVNNGL
360 370 380 390 400
IIMNEFIVPF LPLLLVDEME EKDILAVEDM RNRWCSYLGQ EMEPHLQEKL
410 420 430 440 450
TDFLPKLLDC SMEIKSFHEP PKLPSYSTHE LCERFARIML SLSRTPADGR
Length:450
Mass (Da):52,153
Last modified:December 1, 2001 - v1
Checksum:iDC63EB98F94CCC86
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ010597 Genomic DNA No translation available.
AJ010598 Genomic DNA No translation available.
BC015930 mRNA Translation: AAH15930.1
UniGeneiHs.743994

Genome annotation databases

EnsembliENST00000351097; ENSP00000299574; ENSG00000155313
UCSCiuc010gla.3 human

Similar proteinsi

Entry informationi

Entry nameiQ96B65_HUMAN
AccessioniPrimary (citable) accession number: Q96B65
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: March 28, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health