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Protein

Zinc finger protein 428

Gene

ZNF428

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri161 – 183C2H2-typePROSITE-ProRule annotationAdd BLAST23

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 428
Alternative name(s):
Enzyme-like protein PIT13
Gene namesi
Name:ZNF428
Synonyms:C19orf37
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000131116.11
HGNCiHGNC:20804 ZNF428
neXtProtiNX_Q96B54

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000131116
PharmGKBiPA142672216

Polymorphism and mutation databases

BioMutaiZNF428
DMDMi74760720

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003123461 – 188Zinc finger protein 428Add BLAST188

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei108PhosphothreonineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ96B54
MaxQBiQ96B54
PaxDbiQ96B54
PeptideAtlasiQ96B54
PRIDEiQ96B54

PTM databases

iPTMnetiQ96B54
PhosphoSitePlusiQ96B54

Expressioni

Gene expression databases

BgeeiENSG00000131116
CleanExiHS_ZNF428
ExpressionAtlasiQ96B54 baseline and differential
GenevisibleiQ96B54 HS

Organism-specific databases

HPAiHPA042596
HPA048072

Interactioni

Protein-protein interaction databases

BioGridi125976, 17 interactors
IntActiQ96B54, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliQ96B54
SMRiQ96B54
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi3 – 167Glu-richAdd BLAST165

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri161 – 183C2H2-typePROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG410J37N Eukaryota
ENOG4111CN2 LUCA
GeneTreeiENSGT00390000006595
HOGENOMiHOG000155795
HOVERGENiHBG069038
InParanoidiQ96B54
PhylomeDBiQ96B54
TreeFamiTF337528

Family and domain databases

InterProiView protein in InterPro
IPR038977 ZNF428
IPR013087 Znf_C2H2_type
PANTHERiPTHR36862 PTHR36862, 1 hit
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 1 hit
PS50157 ZINC_FINGER_C2H2_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q96B54-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTETREPAET GGYASLEEDD EDLSPGPEHS SDSEYTLSEP DSEEEEDEEE
60 70 80 90 100
EEEETTDDPE YDPGYKVKQR LGGGRGGPSR RAPRAAQPPA QPCQLCGRSP
110 120 130 140 150
LGEAPPGTPP CRLCCPATAP QEAPAPEGRA LGEEEEEPPR AGEGRPAGRE
160 170 180
EEEEEEEEGT YHCTECEDSF DNLGELHGHF MLHARGEV
Length:188
Mass (Da):20,481
Last modified:March 1, 2004 - v2
Checksum:i31681A8EFE3876F2
GO

Sequence cautioni

The sequence AAC99795 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAP87382 differs from that shown. Intron retention at the C-terminus.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006276 Genomic DNA Translation: AAC99795.1 Sequence problems.
CH471126 Genomic DNA Translation: EAW57210.1
BC015950 mRNA Translation: AAH15950.2
AY257197 mRNA Translation: AAP87382.1 Sequence problems.
CCDSiCCDS12626.1
RefSeqiNP_872304.2, NM_182498.3
UniGeneiHs.99093

Genome annotation databases

EnsembliENST00000300811; ENSP00000300811; ENSG00000131116
GeneIDi126299
KEGGihsa:126299
UCSCiuc002oxa.4 human

Similar proteinsi

Entry informationi

Entry nameiZN428_HUMAN
AccessioniPrimary (citable) accession number: Q96B54
Secondary accession number(s): O95054, Q6X3Y3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: March 1, 2004
Last modified: May 23, 2018
This is version 121 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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