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Protein

BLOC-1-related complex subunit 7

Gene

BORCS7

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor.1 Publication

Miscellaneous

Diaskedin is from the ancient Greek diaskedazo, meaning to disperse.1 Publication

Names & Taxonomyi

Protein namesi
Recommended name:
BLOC-1-related complex subunit 7Curated
Alternative name(s):
Diaskedin1 Publication
Gene namesi
Name:BORCS7Imported
Synonyms:C10orf32Imported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

HGNCiHGNC:23516. BORCS7.

Subcellular locationi

GO - Cellular componenti

  • BORC complex Source: UniProtKB
  • lysosomal membrane Source: UniProtKB-SubCell

Keywords - Cellular componenti

Lysosome, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134928831.

Polymorphism and mutation databases

BioMutaiC10orf32.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000897871 – 105BLOC-1-related complex subunit 7Add BLAST105

Proteomic databases

EPDiQ96B45.
MaxQBiQ96B45.
PaxDbiQ96B45.
PeptideAtlasiQ96B45.
PRIDEiQ96B45.

PTM databases

iPTMnetiQ96B45.
PhosphoSitePlusiQ96B45.

Expressioni

Gene expression databases

BgeeiENSG00000166275.
GenevisibleiQ96B45. HS.

Organism-specific databases

HPAiHPA037648.

Interactioni

Subunit structurei

Component of the BLOC-one-related complex (BORC) which is composed of BLOC1S1, BLOC1S2, BORCS5, BORCS6, BORCS7, BORCS8, KXD1 and SNAPIN.1 Publication

Protein-protein interaction databases

BioGridi125633. 19 interactors.
IntActiQ96B45. 1 interactor.
STRINGi9606.ENSP00000299353.

Family & Domainsi

Sequence similaritiesi

Belongs to the BORCS7 family.Curated

Phylogenomic databases

eggNOGiENOG410IY48. Eukaryota.
ENOG410XVXJ. LUCA.
HOGENOMiHOG000293245.
HOVERGENiHBG054930.
InParanoidiQ96B45.
KOiK20821.
OMAiIQEDAIL.
OrthoDBiEOG091G11TK.
PhylomeDBiQ96B45.
TreeFamiTF314767.

Family and domain databases

InterProiView protein in InterPro
IPR032143. BORCS7.
PfamiView protein in Pfam
PF16088. BORCS7. 1 hit.

Sequencei

Sequence statusi: Complete.

Q96B45-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATGTPESQA RFGQSVKGLL TEKVTTCGTD VIALTKQVLK GSRSSELLGQ
60 70 80 90 100
AARNMVLQED AILHSEDSLR KMAIITTHLQ YQQEAIQKNV EQSSDLQDQL

NHLLK
Length:105
Mass (Da):11,564
Last modified:December 1, 2001 - v1
Checksum:iF123B34D1F10765A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK098071 mRNA. Translation: BAG53576.1.
AK311742 mRNA. Translation: BAG34685.1.
AL832477 mRNA. Translation: CAI46115.1.
AL358790 Genomic DNA. No translation available.
BC015994 mRNA. Translation: AAH15994.1.
RefSeqiNP_001129672.1. NM_001136200.1.
NP_653192.2. NM_144591.3.
UniGeneiHs.34492.

Genome annotation databases

EnsembliENST00000339834; ENSP00000342331; ENSG00000166275.
ENST00000369883; ENSP00000358899; ENSG00000166275.
GeneIDi119032.
KEGGihsa:119032.
UCSCiuc001kwh.3. human.

Similar proteinsi

Entry informationi

Entry nameiBORC7_HUMAN
AccessioniPrimary (citable) accession number: Q96B45
Secondary accession number(s): B2R488, B3KUW4, C9K0X3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: December 1, 2001
Last modified: August 30, 2017
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
  4. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries