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Protein

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit

Gene

PPP2R5C

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.UniRule annotation

GO - Molecular functioni

  • peptidase activity Source: MGI
  • protein phosphatase regulator activity Source: UniProtKB-UniRule

GO - Biological processi

  • protein processing Source: MGI
  • signal transduction Source: InterPro

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunitUniRule annotation
Gene namesi
Name:PPP2R5CImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000078304.19
HGNCiHGNC:9311 PPP2R5C

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000078304

PTM / Processingi

Proteomic databases

MaxQBiQ96B13
PRIDEiQ96B13

Expressioni

Gene expression databases

BgeeiENSG00000078304
ExpressionAtlasiQ96B13 baseline and differential

Structurei

3D structure databases

SMRiQ96B13
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphatase 2A regulatory subunit.UniRule annotation

Phylogenomic databases

eggNOGiKOG2085 Eukaryota
ENOG410XQJW LUCA
GeneTreeiENSGT00550000074525
HOGENOMiHOG000067326
HOVERGENiHBG000009

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002554 PP2A_B56
PANTHERiPTHR10257 PTHR10257, 1 hit
PfamiView protein in Pfam
PF01603 B56, 1 hit
PIRSFiPIRSF028043 PP2A_B56, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

Sequencei

Sequence statusi: Complete.

Q96B13-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLTCNKAGSR MVVDAANSNG PFQPVVLLHI RDVPPADQEK LFIQKLRQCC
60 70 80 90 100
VLFDFVSDPL SDLKWKEVKR AALSEMVEYI THNRNVITEP IYPEVVHMFA
110 120 130 140 150
VNMFRTLPPS SNPTGAEFDP EEDEPTLEAA WPHLQLVYEF FLRFLESPDF
160 170 180 190 200
QPNIAKKYID QKFVLQLLEL FDSEDPRERD FLKTTLHRIY GKFLGLRAYI
210 220 230 240 250
RKQINNIFYR FIYETEHHNG IAELLEILGS IINGFALPLK EEHKIFLLKV
260 270 280 290 300
LLPLHKVKSL SVYHPQLAYC VVQFLEKDST LTEPVVMALL KYWPKTHSPK
310 320 330 340 350
EVMFLNELEE ILDVIEPSEF VKIMEPLFRQ LAKCVSSPHF QVAERALYYW
360 370 380
NNEYIMSLIS DNAAKILPIM FPSLYRNSKT HWNK
Length:384
Mass (Da):44,878
Last modified:December 1, 2001 - v1
Checksum:i262A18D7E909B7C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL118558 Genomic DNA No translation available.
AL137779 Genomic DNA No translation available.
KC877536 Genomic DNA No translation available.
BC016183 mRNA Translation: AAH16183.1
UniGeneiHs.368264

Genome annotation databases

EnsembliENST00000557095; ENSP00000451179; ENSG00000078304
UCSCiuc059fjb.1 human

Similar proteinsi

Entry informationi

Entry nameiQ96B13_HUMAN
AccessioniPrimary (citable) accession number: Q96B13
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: May 23, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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