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Protein

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit

Gene

PPP2R5C

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.Curated

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunitCurated
Gene namesi
Name:PPP2R5C0 Publication
OrganismiHomo sapiens (Human)0 Publication
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000078304.19.
HGNCiHGNC:9311. PPP2R5C.

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000078304.

PTM / Processingi

Proteomic databases

MaxQBiQ96B13.

Expressioni

Gene expression databases

BgeeiENSG00000078304.

Structurei

3D structure databases

SMRiQ96B13.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphatase 2A regulatory subunit.Curated

Phylogenomic databases

eggNOGiKOG2085. Eukaryota.
ENOG410XQJW. LUCA.
GeneTreeiENSGT00550000074525.
HOGENOMiHOG000067326.
HOVERGENiHBG000009.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiView protein in InterPro
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR002554. PP2A_B56.
PANTHERiPTHR10257. PTHR10257. 1 hit.
PfamiView protein in Pfam
PF01603. B56. 1 hit.
PIRSFiPIRSF028043. PP2A_B56. 1 hit.
SUPFAMiSSF48371. SSF48371. 1 hit.

Sequencei

Sequence statusi: Complete.

Q96B13-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLTCNKAGSR MVVDAANSNG PFQPVVLLHI RDVPPADQEK LFIQKLRQCC
60 70 80 90 100
VLFDFVSDPL SDLKWKEVKR AALSEMVEYI THNRNVITEP IYPEVVHMFA
110 120 130 140 150
VNMFRTLPPS SNPTGAEFDP EEDEPTLEAA WPHLQLVYEF FLRFLESPDF
160 170 180 190 200
QPNIAKKYID QKFVLQLLEL FDSEDPRERD FLKTTLHRIY GKFLGLRAYI
210 220 230 240 250
RKQINNIFYR FIYETEHHNG IAELLEILGS IINGFALPLK EEHKIFLLKV
260 270 280 290 300
LLPLHKVKSL SVYHPQLAYC VVQFLEKDST LTEPVVMALL KYWPKTHSPK
310 320 330 340 350
EVMFLNELEE ILDVIEPSEF VKIMEPLFRQ LAKCVSSPHF QVAERALYYW
360 370 380
NNEYIMSLIS DNAAKILPIM FPSLYRNSKT HWNK
Length:384
Mass (Da):44,878
Last modified:December 1, 2001 - v1
Checksum:i262A18D7E909B7C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL118558 Genomic DNA. No translation available.
AL137779 Genomic DNA. No translation available.
KC877536 Genomic DNA. No translation available.
BC016183 mRNA. Translation: AAH16183.1.
UniGeneiHs.368264.

Genome annotation databases

EnsembliENST00000557095; ENSP00000451179; ENSG00000078304.
UCSCiuc059fjb.1. human.

Similar proteinsi

Entry informationi

Entry nameiQ96B13_HUMAN
AccessioniPrimary (citable) accession number: Q96B13
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: November 22, 2017
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationIEA:, Reference proteome0 Publication