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Protein

Protein FAM131C

Gene

FAM131C

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM131C
Gene namesi
Name:FAM131C
Synonyms:C1orf117
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000185519.8
HGNCiHGNC:26717 FAM131C
neXtProtiNX_Q96AQ9

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000185519
PharmGKBiPA162386082

Polymorphism and mutation databases

BioMutaiFAM131C
DMDMi134035394

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002804011 – 280Protein FAM131CAdd BLAST280

Proteomic databases

PaxDbiQ96AQ9
PeptideAtlasiQ96AQ9
PRIDEiQ96AQ9
ProteomicsDBi75995

PTM databases

iPTMnetiQ96AQ9
PhosphoSitePlusiQ96AQ9

Expressioni

Gene expression databases

BgeeiENSG00000185519
CleanExiHS_FAM131C
GenevisibleiQ96AQ9 HS

Organism-specific databases

HPAiHPA031046

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi131523, 11 interactors
IntActiQ96AQ9, 7 interactors
STRINGi9606.ENSP00000364814

Structurei

3D structure databases

ProteinModelPortaliQ96AQ9
SMRiQ96AQ9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi214 – 264Pro-richAdd BLAST51

Sequence similaritiesi

Belongs to the FAM131 family.Curated

Phylogenomic databases

eggNOGiENOG410IKD9 Eukaryota
ENOG41120RD LUCA
GeneTreeiENSGT00390000015421
HOGENOMiHOG000231296
HOVERGENiHBG080216
InParanoidiQ96AQ9
OMAiEDEHYCC
OrthoDBiEOG091G0LKD
PhylomeDBiQ96AQ9
TreeFamiTF331537

Family and domain databases

InterProiView protein in InterPro
IPR026782 FAM131
PANTHERiPTHR15736 PTHR15736, 1 hit
PfamiView protein in Pfam
PF15010 FAM131, 1 hit

Sequencei

Sequence statusi: Complete.

Q96AQ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSCVSRDLF TSAHKNCPMP QGADPLNPDL PSGRTPTVAP DCVIGKDKQM
60 70 80 90 100
DFCWDPWQRC FQTTNGYLSD SRSRPGNYNV AALATSSLVG VVQSIKDHIT
110 120 130 140 150
KPTAMARGRV AHLIEWKGWS AQPAGWELSP AEDEHYCCLP DELREARFAA
160 170 180 190 200
GVAEQFAITE ATLSAWSSLD EEELHPENSP QGIVQLQDLE SIYLQDSLPS
210 220 230 240 250
GPSQDDSLQA FSSPSPSPDS CPSPEEPPST AGIPQPPSPE LQHRRRLPGA
260 270 280
QGPEGGTHPP GSLPSMDSGS LWEEDEVFYN
Length:280
Mass (Da):30,351
Last modified:March 20, 2007 - v2
Checksum:i674631222FA8095C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti19M → I in BAC04282 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_03113048K → E2 PublicationsCorresponds to variant dbSNP:rs2863458Ensembl.1
Natural variantiVAR_031131107R → Q1 PublicationCorresponds to variant dbSNP:rs71510977Ensembl.1
Natural variantiVAR_031132123P → R2 PublicationsCorresponds to variant dbSNP:rs11576236Ensembl.1
Natural variantiVAR_031133215S → I. Corresponds to variant dbSNP:rs1832151Ensembl.1
Natural variantiVAR_031134226E → D1 PublicationCorresponds to variant dbSNP:rs17853749Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK094085 mRNA Translation: BAC04282.1
AL355994 Genomic DNA No translation available.
BC016848 mRNA Translation: AAH16848.1
BC037394 mRNA Translation: AAH37394.1
CCDSiCCDS41270.1
RefSeqiNP_872429.2, NM_182623.2
UniGeneiHs.126825

Genome annotation databases

EnsembliENST00000375662; ENSP00000364814; ENSG00000185519
GeneIDi348487
KEGGihsa:348487
UCSCiuc001axz.5 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiF131C_HUMAN
AccessioniPrimary (citable) accession number: Q96AQ9
Secondary accession number(s): Q5T5Q5, Q8N3X3, Q8N9P9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: March 20, 2007
Last modified: June 20, 2018
This is version 100 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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