Q96AQ3 (Q96AQ3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
ATF4 protein EMBL CAG30270.1

Submitted name:
Activating transcription factor 4 (Tax-responsive enhancer element B67) EMBL AAH16855.1
Submitted name:
Activating transcription factor 4 (Tax-responsive enhancer element B67), isoform CRA_a EMBL EAW60341.1

Gene names

Name:	ATF4 EMBL AAH16855.1
ORF Names:	hCG_41721 EMBL EAW60341.1

Organism

Homo sapiens (Human) EMBL AAH16855.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	351 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the bZIP family. RuleBase RU000470

Ontologies

Keywords
Cellular component	Nucleus RuleBase RU000470
Ligand	DNA-binding RuleBase RU000470
Gene Ontology (GO)
Molecular function	protein dimerization activity Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q96AQ3 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 3BBB7379DC3B0D07	FASTA	351	38,590
	10 20 30 40 50 60 MTEMSFLSSE VLVGDLMSPF DQSGLGAEES LGLLDDYLEV AKHFKPHGFS SDKAKAGSSE 70 80 90 100 110 120 WLAVDGLVSP SNNSKEDAFS GTDWMLEKMD LKEFDLDALL GIDDLETMPD DLLTTLDDTC 130 140 150 160 170 180 DLFAPLVQET NKQPPQTVNP IGHLPESLTK PDQVAPFTFL QPLPLSPGVL SSTPDHSFSL 190 200 210 220 230 240 ELGSEVDITE GDRKPDYTAY VAMIPQCIKE EDTPSDNDSG ICMSPESYLG SPQHSPSTRG 250 260 270 280 290 300 SPNRSLPSPG VLCGSARPKP YDPPGEKMVA AKVKGEKLDK KLKKMEQNKT AATRYRQKKR 310 320 330 340 350 AEQEALTGEC KELEKKNEAL KERADSLAKE IQYLKDLIEE VRKARGKKRV P

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A genome annotation-driven approach to cloning the human ORFeome." Collins J.E., Wright C.L., Edwards C.A., Davis M.P., Grinham J.A., Cole C.G., Goward M.E., Aguado B., Mallya M., Mokrab Y., Huckle E.J., Beare D.M., Dunham I. Genome Biol. 5:R84-R84(2004) Cited for: NUCLEOTIDE SEQUENCE.
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Bladder EMBL AAH44895.1, Colon EMBL AAH16855.1 and Ovary EMBL AAH22088.1.
[3]	Collins J.E., Wright C.L., Edwards C.A., Davis M.P., Grinham J.A., Cole C.G., Goward M.E., Aguado B., Mallya M., Mokrab Y., Huckle E.J., Beare D.M., Dunham I. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[4]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC016855 mRNA. Translation: AAH16855.1. BC022088 mRNA. Translation: AAH22088.1. BC044895 mRNA. Translation: AAH44895.1. BC073754 mRNA. Translation: AAH73754.1. CR456384 mRNA. Translation: CAG30270.1. CH471095 Genomic DNA. Translation: EAW60341.1.
IPI	IPI00002503.
RefSeq	NP_001666.2. NM_001675.2. NP_877962.1. NM_182810.1.
UniGene	Hs.496487.
3D structure databases
HSSP	HSSP built from PDB template 1CI6 based on UniProtKB P18848.
ProteinModelPortal	Q96AQ3.
SMR	Q96AQ3. Positions 286-341.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q96AQ3. 5 interactions.
MINT	MINT-1440344.
STRING	Q96AQ3.
Proteomic databases
PRIDE	Q96AQ3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	468.
KEGG	hsa:468.
Organism-specific databases
CTD	468.
Phylogenomic databases
GeneTree	ENSGT00530000063801.
HOVERGEN	HBG004301.
OMA	YLGSPQH.
PhylomeDB	Q96AQ3.
Gene expression databases
ArrayExpress	Q96AQ3.
Bgee	Q96AQ3.
Family and domain databases
InterPro	IPR004827. bZIP. IPR011616. bZIP_1. [Graphical view]
KO	K04374.
Pfam	PF00170. bZIP_1. 1 hit. [Graphical view]
SMART	SM00338. BRLZ. 1 hit. [Graphical view]
PROSITE	PS50217. BZIP. 1 hit. PS00036. BZIP_BASIC. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	1935.

Entry information

Entry name

Q96AQ3_HUMAN

Accession

Primary (citable) accession number: Q96AQ3

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	December 14, 2011
This is version 81 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.