Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q96A35

- RM24_HUMAN

UniProt

Q96A35 - RM24_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

39S ribosomal protein L24, mitochondrial

Gene

MRPL24

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
39S ribosomal protein L24, mitochondrial
Short name:
L24mt
Short name:
MRP-L24
Gene namesi
Name:MRPL24
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 1

Organism-specific databases

HGNCiHGNC:14037. MRPL24.

Subcellular locationi

Mitochondrion By similarity

GO - Cellular componenti

  1. mitochondrion Source: UniProtKB-KW
  2. ribosome Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA30954.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 99MitochondrionBy similarity
Chaini10 – 21620739S ribosomal protein L24, mitochondrialPRO_0000270488Add
BLAST

Proteomic databases

MaxQBiQ96A35.
PaxDbiQ96A35.
PRIDEiQ96A35.

PTM databases

PhosphoSiteiQ96A35.

Expressioni

Gene expression databases

BgeeiQ96A35.
CleanExiHS_MRPL24.
ExpressionAtlasiQ96A35. baseline and differential.
GenevestigatoriQ96A35.

Organism-specific databases

HPAiHPA030295.

Interactioni

Protein-protein interaction databases

BioGridi122732. 35 interactions.
IntActiQ96A35. 2 interactions.
MINTiMINT-6942170.
STRINGi9606.ENSP00000354525.

Structurei

3D structure databases

ProteinModelPortaliQ96A35.
SMRiQ96A35. Positions 53-155.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini56 – 8934KOWAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi40 – 434Poly-Arg

Sequence similaritiesi

Belongs to the ribosomal protein L24P family.Curated
Contains 1 KOW domain.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiCOG0198.
GeneTreeiENSGT00390000014542.
HOVERGENiHBG093899.
InParanoidiQ96A35.
KOiK02895.
OMAiGIQETRR.
OrthoDBiEOG7JQBP1.
PhylomeDBiQ96A35.
TreeFamiTF105984.

Family and domain databases

Gene3Di2.30.30.30. 1 hit.
InterProiIPR005824. KOW.
IPR014722. Rib_L2_dom2.
IPR003256. Ribosomal_L24.
IPR005825. Ribosomal_L24/26_CS.
IPR008991. Translation_prot_SH3-like.
[Graphical view]
PANTHERiPTHR12903. PTHR12903. 1 hit.
PfamiPF00467. KOW. 1 hit.
[Graphical view]
SMARTiSM00739. KOW. 1 hit.
[Graphical view]
SUPFAMiSSF50104. SSF50104. 1 hit.
TIGRFAMsiTIGR01079. rplX_bact. 1 hit.
PROSITEiPS01108. RIBOSOMAL_L24. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q96A35-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRLSALLALA SKVTLPPHYR YGMSPPGSVA DKRKNPPWIR RRPVVVEPIS
60 70 80 90 100
DEDWYLFCGD TVEILEGKDA GKQGKVVQVI RQRNWVVVGG LNTHYRYIGK
110 120 130 140 150
TMDYRGTMIP SEAPLLHRQV KLVDPMDRKP TEIEWRFTEA GERVRVSTRS
160 170 180 190 200
GRIIPKPEFP RADGIVPETW IDGPKDTSVE DALERTYVPC LKTLQEEVME
210
AMGIKETRKY KKVYWY
Length:216
Mass (Da):24,915
Last modified:December 1, 2001 - v1
Checksum:i2A1F5C88001557D0
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti109 – 1091I → V in BAB14929. (PubMed:14702039)Curated
Sequence conflicti109 – 1091I → V in BAD96220. 1 PublicationCurated
Sequence conflicti119 – 1191Q → H in BAB14929. (PubMed:14702039)Curated
Sequence conflicti134 – 1341E → D in BAB14929. (PubMed:14702039)Curated
Sequence conflicti142 – 1421E → Q in BAB14929. (PubMed:14702039)Curated
Sequence conflicti208 – 2081R → Q in BAD96786. 1 PublicationCurated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK024570 mRNA. Translation: BAB14929.1.
CR457329 mRNA. Translation: CAG33610.1.
AK222500 mRNA. Translation: BAD96220.1.
AK223066 mRNA. Translation: BAD96786.1.
AL590666 Genomic DNA. Translation: CAI16343.1.
AL590666 Genomic DNA. Translation: CAI16344.1.
AL590666 Genomic DNA. Translation: CAI16345.1.
AL590666 Genomic DNA. Translation: CAI16346.1.
CH471121 Genomic DNA. Translation: EAW52913.1.
CH471121 Genomic DNA. Translation: EAW52914.1.
BC012440 mRNA. Translation: AAH12440.1.
BC016700 mRNA. Translation: AAH16700.1.
AB051341 Genomic DNA. Translation: BAB54931.2.
CCDSiCCDS1155.1.
RefSeqiNP_078816.2. NM_024540.3.
NP_663781.1. NM_145729.2.
UniGeneiHs.418233.

Genome annotation databases

EnsembliENST00000361531; ENSP00000354525; ENSG00000143314.
ENST00000368211; ENSP00000357194; ENSG00000143314.
GeneIDi79590.
KEGGihsa:79590.
UCSCiuc001fpw.1. human.

Polymorphism databases

DMDMi74751733.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK024570 mRNA. Translation: BAB14929.1 .
CR457329 mRNA. Translation: CAG33610.1 .
AK222500 mRNA. Translation: BAD96220.1 .
AK223066 mRNA. Translation: BAD96786.1 .
AL590666 Genomic DNA. Translation: CAI16343.1 .
AL590666 Genomic DNA. Translation: CAI16344.1 .
AL590666 Genomic DNA. Translation: CAI16345.1 .
AL590666 Genomic DNA. Translation: CAI16346.1 .
CH471121 Genomic DNA. Translation: EAW52913.1 .
CH471121 Genomic DNA. Translation: EAW52914.1 .
BC012440 mRNA. Translation: AAH12440.1 .
BC016700 mRNA. Translation: AAH16700.1 .
AB051341 Genomic DNA. Translation: BAB54931.2 .
CCDSi CCDS1155.1.
RefSeqi NP_078816.2. NM_024540.3.
NP_663781.1. NM_145729.2.
UniGenei Hs.418233.

3D structure databases

ProteinModelPortali Q96A35.
SMRi Q96A35. Positions 53-155.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 122732. 35 interactions.
IntActi Q96A35. 2 interactions.
MINTi MINT-6942170.
STRINGi 9606.ENSP00000354525.

PTM databases

PhosphoSitei Q96A35.

Polymorphism databases

DMDMi 74751733.

Proteomic databases

MaxQBi Q96A35.
PaxDbi Q96A35.
PRIDEi Q96A35.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000361531 ; ENSP00000354525 ; ENSG00000143314 .
ENST00000368211 ; ENSP00000357194 ; ENSG00000143314 .
GeneIDi 79590.
KEGGi hsa:79590.
UCSCi uc001fpw.1. human.

Organism-specific databases

CTDi 79590.
GeneCardsi GC01M156707.
HGNCi HGNC:14037. MRPL24.
HPAi HPA030295.
MIMi 611836. gene.
neXtProti NX_Q96A35.
PharmGKBi PA30954.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG0198.
GeneTreei ENSGT00390000014542.
HOVERGENi HBG093899.
InParanoidi Q96A35.
KOi K02895.
OMAi GIQETRR.
OrthoDBi EOG7JQBP1.
PhylomeDBi Q96A35.
TreeFami TF105984.

Miscellaneous databases

GeneWikii MRPL24.
GenomeRNAii 79590.
NextBioi 68600.
PROi Q96A35.
SOURCEi Search...

Gene expression databases

Bgeei Q96A35.
CleanExi HS_MRPL24.
ExpressionAtlasi Q96A35. baseline and differential.
Genevestigatori Q96A35.

Family and domain databases

Gene3Di 2.30.30.30. 1 hit.
InterProi IPR005824. KOW.
IPR014722. Rib_L2_dom2.
IPR003256. Ribosomal_L24.
IPR005825. Ribosomal_L24/26_CS.
IPR008991. Translation_prot_SH3-like.
[Graphical view ]
PANTHERi PTHR12903. PTHR12903. 1 hit.
Pfami PF00467. KOW. 1 hit.
[Graphical view ]
SMARTi SM00739. KOW. 1 hit.
[Graphical view ]
SUPFAMi SSF50104. SSF50104. 1 hit.
TIGRFAMsi TIGR01079. rplX_bact. 1 hit.
PROSITEi PS01108. RIBOSOMAL_L24. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Adipose tissue.
  2. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
    Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
    Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  3. Suzuki Y., Sugano S., Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S.
    Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Adipose tissue.
  4. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Bone marrow and Ovary.
  7. "The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders."
    Kenmochi N., Suzuki T., Uechi T., Magoori M., Kuniba M., Higa S., Watanabe K., Tanaka T.
    Genomics 77:65-70(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 129-216.
  8. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiRM24_HUMAN
AccessioniPrimary (citable) accession number: Q96A35
Secondary accession number(s): D3DVC8
, Q53G65, Q53HT0, Q5SYZ9, Q5SZ00, Q5SZ02, Q96Q70, Q9H7G3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: December 1, 2001
Last modified: October 29, 2014
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3