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Protein

Uncharacterized protein C11orf52

Gene

C11orf52

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C11orf52
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 11

Organism-specific databases

HGNCiHGNC:30531. C11orf52.

Subcellular locationi

GO - Cellular componenti

  1. extracellular vesicular exosome Source: UniProtKB
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA143485347.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 123123Uncharacterized protein C11orf52PRO_0000263609Add
BLAST

Proteomic databases

PaxDbiQ96A22.
PRIDEiQ96A22.

PTM databases

PhosphoSiteiQ96A22.

Expressioni

Gene expression databases

BgeeiQ96A22.
CleanExiHS_C11orf52.
ExpressionAtlasiQ96A22. baseline.
GenevestigatoriQ96A22.

Organism-specific databases

HPAiHPA038387.

Interactioni

Protein-protein interaction databases

BioGridi124891. 2 interactions.
IntActiQ96A22. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ96A22.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG41312.
GeneTreeiENSGT00390000015195.
HOGENOMiHOG000111731.
HOVERGENiHBG081214.
InParanoidiQ96A22.
OMAiHTYERVL.
PhylomeDBiQ96A22.
TreeFamiTF336887.

Family and domain databases

InterProiIPR028106. DUF4578.
[Graphical view]
PfamiPF15147. DUF4578. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q96A22-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGNRVCCGGS WSCPSTFQKK KKTGSQTRRT LKPQPQQLQQ NLPKGHETTG
60 70 80 90 100
HTYERVLQQQ GSQERSPGLM SEDSNLHYAD IQVCSRPHAR EVKHVHLENA
110 120
TEYATLRFPQ ATPRYDSKNG TLV
Length:123
Mass (Da):13,921
Last modified:December 4, 2007 - v2
Checksum:i481C3A554E64B33D
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti23 – 231T → R.2 Publications
Corresponds to variant rs7124407 [ dbSNP | Ensembl ].
VAR_029587

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK057948 mRNA. Translation: BAB71620.1.
AP000907 Genomic DNA. No translation available.
BC008501 mRNA. Translation: AAH08501.1.
BC110872 mRNA. Translation: AAI10873.1.
CCDSiCCDS8353.1.
RefSeqiNP_542390.2. NM_080659.2.
UniGeneiHs.97013.

Genome annotation databases

EnsembliENST00000278601; ENSP00000278601; ENSG00000149300.
GeneIDi91894.
KEGGihsa:91894.
UCSCiuc001pmh.3. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK057948 mRNA. Translation: BAB71620.1.
AP000907 Genomic DNA. No translation available.
BC008501 mRNA. Translation: AAH08501.1.
BC110872 mRNA. Translation: AAI10873.1.
CCDSiCCDS8353.1.
RefSeqiNP_542390.2. NM_080659.2.
UniGeneiHs.97013.

3D structure databases

ProteinModelPortaliQ96A22.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi124891. 2 interactions.
IntActiQ96A22. 1 interaction.

PTM databases

PhosphoSiteiQ96A22.

Proteomic databases

PaxDbiQ96A22.
PRIDEiQ96A22.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000278601; ENSP00000278601; ENSG00000149300.
GeneIDi91894.
KEGGihsa:91894.
UCSCiuc001pmh.3. human.

Organism-specific databases

CTDi91894.
GeneCardsiGC11P111789.
HGNCiHGNC:30531. C11orf52.
HPAiHPA038387.
neXtProtiNX_Q96A22.
PharmGKBiPA143485347.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG41312.
GeneTreeiENSGT00390000015195.
HOGENOMiHOG000111731.
HOVERGENiHBG081214.
InParanoidiQ96A22.
OMAiHTYERVL.
PhylomeDBiQ96A22.
TreeFamiTF336887.

Miscellaneous databases

GenomeRNAii91894.
NextBioi77515.

Gene expression databases

BgeeiQ96A22.
CleanExiHS_C11orf52.
ExpressionAtlasiQ96A22. baseline.
GenevestigatoriQ96A22.

Family and domain databases

InterProiIPR028106. DUF4578.
[Graphical view]
PfamiPF15147. DUF4578. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ARG-23.
    Tissue: Gastric mucosa.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ARG-23.
    Tissue: PNS and Prostate.

Entry informationi

Entry nameiCK052_HUMAN
AccessioniPrimary (citable) accession number: Q96A22
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: December 4, 2007
Last modified: January 7, 2015
This is version 86 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.