Q969S9 (RRF2M_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosome-releasing factor 2, mitochondrial
Short name=RRF2mt

Alternative name(s):
Elongation factor G 2, mitochondrial
Short name=EF-G2mt
Short name=mEF-G 2
Elongation factor G2
Short name=hEFG2

Gene names

Name:	GFM2
Synonyms:	EFG2
ORF Names:	MSTP027

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	779 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation. Ref.7
Subcellular location	Mitochondrion By similarity.
Tissue specificity	Widely expressed. Ref.1
Sequence similarities	Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Mitochondrion
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Transit peptide
Ligand	GTP-binding Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	mitochondrial translation Inferred from direct assay Ref.7. Source: UniProtKB ribosome disassembly Inferred from direct assay Ref.7. Source: UniProtKB
Cellular_component	mitochondrion Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	GTP binding Inferred from electronic annotation. Source: UniProtKB-KW GTPase activity Inferred from direct assay Ref.7. Source: UniProtKB
Complete GO annotation...

Alternative products

This entry describes 5 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q969S9-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q969S9-2)

The sequence of this isoform differs from the canonical sequence as follows:
     361-407: Missing.

Note: No experimental confirmation available.

Isoform 3 (identifier: Q969S9-3)

The sequence of this isoform differs from the canonical sequence as follows:
     608-609: Missing.

Note: No experimental confirmation available.

Isoform 4 (identifier: Q969S9-4)

The sequence of this isoform differs from the canonical sequence as follows:
     530-531: TV → IP
     532-709: Missing.

Note: No experimental confirmation available.

Isoform 5 (identifier: Q969S9-5)

The sequence of this isoform differs from the canonical sequence as follows:
     504-513: DLEHALKCLQ → GINGLSVSTN
     514-779: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – ?		Mitochondrion Potential
	Chain	? – 779		Ribosome-releasing factor 2, mitochondrial		PRO_0000007450
Regions
	Nucleotide binding	77 – 84	8	GTP By similarity
	Nucleotide binding	141 – 145	5	GTP By similarity
	Nucleotide binding	195 – 198	4	GTP By similarity
Natural variations
	Alternative sequence	361 – 407	47	Missing in isoform 2.		VSP_001363
	Alternative sequence	504 – 513	10	DLEHALKCLQ → GINGLSVSTN in isoform 5.		VSP_038190
	Alternative sequence	514 – 779	266	Missing in isoform 5.		VSP_038191
	Alternative sequence	530 – 531	2	TV → IP in isoform 4.		VSP_038192
	Alternative sequence	532 – 709	178	Missing in isoform 4.		VSP_038193
	Alternative sequence	608 – 609	2	Missing in isoform 3.		VSP_038194
	Natural variant	64	1	N → S. Corresponds to variant rs957680 [ dbSNP | Ensembl ].		VAR_053983
	Natural variant	300	1	S → C. Corresponds to variant rs16872235 [ dbSNP | Ensembl ].		VAR_053984
	Natural variant	425	1	P → H. Ref.6 Corresponds to variant rs17852780 [ dbSNP | Ensembl ].		VAR_060200
	Natural variant	594	1	E → G. Ref.6 Corresponds to variant rs17856872 [ dbSNP | Ensembl ].		VAR_060201
	Natural variant	735	1	E → G. Ref.6 Corresponds to variant rs17856871 [ dbSNP | Ensembl ].		VAR_060202
	Natural variant	774	1	R → Q. Corresponds to variant rs1048167 [ dbSNP | Ensembl ].		VAR_053985
Experimental info
	Sequence conflict	59	1	L → I in AAH30612. Ref.6
	Sequence conflict	201	1	G → V in AAS49035. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 856B4E26FD9DD94E	FASTA	779	86,601
	10 20 30 40 50 60 MLTNLRIFAM SHQTIPSVYI NNICCYKIRA SLKRLKPHVP LGRNCSSLPG LIGNDIKSLH 70 80 90 100 110 120 SIINPPIAKI RNIGIMAHID AGKTTTTERI LYYSGYTRSL GDVDDGDTVT DFMAQERERG 130 140 150 160 170 180 ITIQSAAVTF DWKGYRVNLI DTPGHVDFTL EVERCLRVLD GAVAVFDASA GVEAQTLTVW 190 200 210 220 230 240 RQADKHNIPR ICFLNKMDKT GASFKYAVES IREKLKAKPL LLQLPIGEAK TFKGVVDVVM 250 260 270 280 290 300 KEKLLWNCNS NDGKDFERKP LLEMNDPELL KETTEARNAL IEQVADLDDE FADLVLEEFS 310 320 330 340 350 360 ENFDLLPAEK LQTAIHRVTL AQTAVPVLCG SALKNKGIQP LLDAVTMYLP SPEERNYEFL 370 380 390 400 410 420 QWYKDDLCAL AFKVLHDKQR GPLVFMRIYS GTIKPQLAIH NINGNCTERI SRLLLPFADQ 430 440 450 460 470 480 HVEIPSLTAG NIALTVGLKH TATGDTIVSS KSSALAAARR AEREGEKKHR QNNEAERLLL 490 500 510 520 530 540 AGVEIPEPVF FCTIEPPSLS KQPDLEHALK CLQREDPSLK VRLDPDSGQT VLCGMGELHI 550 560 570 580 590 600 EIIHDRIKRE YGLETYLGPL QVAYRETILN SVRATDTLDR TLGDKRHLVT VEVEARPIET 610 620 630 640 650 660 SSVMPVIEFE YAESINEGLL KVSQEAIENG IHSACLQGPL LGSPIQDVAI TLHSLTIHPG 670 680 690 700 710 720 TSTTMISACV SRCVQKALKK ADKQVLEPLM NLEVTVARDY LSPVLADLAQ RRGNIQEIQT 730 740 750 760 770 RQDNKVVIGF VPLAEIMGYS TVLRTLTSGS ATFALELSTY QAMNPQDQNT LLNRRSGLT
	Isoform 2 [UniParc]. Checksum: 15869E090CB0848A	FASTA	732	81,200
	10 20 30 40 50 60 MLTNLRIFAM SHQTIPSVYI NNICCYKIRA SLKRLKPHVP LGRNCSSLPG LIGNDIKSLH 70 80 90 100 110 120 SIINPPIAKI RNIGIMAHID AGKTTTTERI LYYSGYTRSL GDVDDGDTVT DFMAQERERG 130 140 150 160 170 180 ITIQSAAVTF DWKGYRVNLI DTPGHVDFTL EVERCLRVLD GAVAVFDASA GVEAQTLTVW 190 200 210 220 230 240 RQADKHNIPR ICFLNKMDKT GASFKYAVES IREKLKAKPL LLQLPIGEAK TFKGVVDVVM 250 260 270 280 290 300 KEKLLWNCNS NDGKDFERKP LLEMNDPELL KETTEARNAL IEQVADLDDE FADLVLEEFS 310 320 330 340 350 360 ENFDLLPAEK LQTAIHRVTL AQTAVPVLCG SALKNKGIQP LLDAVTMYLP SPEERNYEFL 370 380 390 400 410 420 ERISRLLLPF ADQHVEIPSL TAGNIALTVG LKHTATGDTI VSSKSSALAA ARRAEREGEK 430 440 450 460 470 480 KHRQNNEAER LLLAGVEIPE PVFFCTIEPP SLSKQPDLEH ALKCLQREDP SLKVRLDPDS 490 500 510 520 530 540 GQTVLCGMGE LHIEIIHDRI KREYGLETYL GPLQVAYRET ILNSVRATDT LDRTLGDKRH 550 560 570 580 590 600 LVTVEVEARP IETSSVMPVI EFEYAESINE GLLKVSQEAI ENGIHSACLQ GPLLGSPIQD 610 620 630 640 650 660 VAITLHSLTI HPGTSTTMIS ACVSRCVQKA LKKADKQVLE PLMNLEVTVA RDYLSPVLAD 670 680 690 700 710 720 LAQRRGNIQE IQTRQDNKVV IGFVPLAEIM GYSTVLRTLT SGSATFALEL STYQAMNPQD 730 QNTLLNRRSG LT
	Isoform 3 [UniParc]. Checksum: 539970B070FB4904	FASTA	777	86,324
	10 20 30 40 50 60 MLTNLRIFAM SHQTIPSVYI NNICCYKIRA SLKRLKPHVP LGRNCSSLPG LIGNDIKSLH 70 80 90 100 110 120 SIINPPIAKI RNIGIMAHID AGKTTTTERI LYYSGYTRSL GDVDDGDTVT DFMAQERERG 130 140 150 160 170 180 ITIQSAAVTF DWKGYRVNLI DTPGHVDFTL EVERCLRVLD GAVAVFDASA GVEAQTLTVW 190 200 210 220 230 240 RQADKHNIPR ICFLNKMDKT GASFKYAVES IREKLKAKPL LLQLPIGEAK TFKGVVDVVM 250 260 270 280 290 300 KEKLLWNCNS NDGKDFERKP LLEMNDPELL KETTEARNAL IEQVADLDDE FADLVLEEFS 310 320 330 340 350 360 ENFDLLPAEK LQTAIHRVTL AQTAVPVLCG SALKNKGIQP LLDAVTMYLP SPEERNYEFL 370 380 390 400 410 420 QWYKDDLCAL AFKVLHDKQR GPLVFMRIYS GTIKPQLAIH NINGNCTERI SRLLLPFADQ 430 440 450 460 470 480 HVEIPSLTAG NIALTVGLKH TATGDTIVSS KSSALAAARR AEREGEKKHR QNNEAERLLL 490 500 510 520 530 540 AGVEIPEPVF FCTIEPPSLS KQPDLEHALK CLQREDPSLK VRLDPDSGQT VLCGMGELHI 550 560 570 580 590 600 EIIHDRIKRE YGLETYLGPL QVAYRETILN SVRATDTLDR TLGDKRHLVT VEVEARPIET 610 620 630 640 650 660 SSVMPVIEYA ESINEGLLKV SQEAIENGIH SACLQGPLLG SPIQDVAITL HSLTIHPGTS 670 680 690 700 710 720 TTMISACVSR CVQKALKKAD KQVLEPLMNL EVTVARDYLS PVLADLAQRR GNIQEIQTRQ 730 740 750 760 770 DNKVVIGFVP LAEIMGYSTV LRTLTSGSAT FALELSTYQA MNPQDQNTLL NRRSGLT
	Isoform 4 [UniParc]. Checksum: C712D5773F21E83E	FASTA	601	67,068
	10 20 30 40 50 60 MLTNLRIFAM SHQTIPSVYI NNICCYKIRA SLKRLKPHVP LGRNCSSLPG LIGNDIKSLH 70 80 90 100 110 120 SIINPPIAKI RNIGIMAHID AGKTTTTERI LYYSGYTRSL GDVDDGDTVT DFMAQERERG 130 140 150 160 170 180 ITIQSAAVTF DWKGYRVNLI DTPGHVDFTL EVERCLRVLD GAVAVFDASA GVEAQTLTVW 190 200 210 220 230 240 RQADKHNIPR ICFLNKMDKT GASFKYAVES IREKLKAKPL LLQLPIGEAK TFKGVVDVVM 250 260 270 280 290 300 KEKLLWNCNS NDGKDFERKP LLEMNDPELL KETTEARNAL IEQVADLDDE FADLVLEEFS 310 320 330 340 350 360 ENFDLLPAEK LQTAIHRVTL AQTAVPVLCG SALKNKGIQP LLDAVTMYLP SPEERNYEFL 370 380 390 400 410 420 QWYKDDLCAL AFKVLHDKQR GPLVFMRIYS GTIKPQLAIH NINGNCTERI SRLLLPFADQ 430 440 450 460 470 480 HVEIPSLTAG NIALTVGLKH TATGDTIVSS KSSALAAARR AEREGEKKHR QNNEAERLLL 490 500 510 520 530 540 AGVEIPEPVF FCTIEPPSLS KQPDLEHALK CLQREDPSLK VRLDPDSGQI PQRRGNIQEI 550 560 570 580 590 600 QTRQDNKVVI GFVPLAEIMG YSTVLRTLTS GSATFALELS TYQAMNPQDQ NTLLNRRSGL T
	Isoform 5 [UniParc]. Checksum: 81B3AF2019E9D71F	FASTA	513	57,060
	10 20 30 40 50 60 MLTNLRIFAM SHQTIPSVYI NNICCYKIRA SLKRLKPHVP LGRNCSSLPG LIGNDIKSLH 70 80 90 100 110 120 SIINPPIAKI RNIGIMAHID AGKTTTTERI LYYSGYTRSL GDVDDGDTVT DFMAQERERG 130 140 150 160 170 180 ITIQSAAVTF DWKGYRVNLI DTPGHVDFTL EVERCLRVLD GAVAVFDASA GVEAQTLTVW 190 200 210 220 230 240 RQADKHNIPR ICFLNKMDKT GASFKYAVES IREKLKAKPL LLQLPIGEAK TFKGVVDVVM 250 260 270 280 290 300 KEKLLWNCNS NDGKDFERKP LLEMNDPELL KETTEARNAL IEQVADLDDE FADLVLEEFS 310 320 330 340 350 360 ENFDLLPAEK LQTAIHRVTL AQTAVPVLCG SALKNKGIQP LLDAVTMYLP SPEERNYEFL 370 380 390 400 410 420 QWYKDDLCAL AFKVLHDKQR GPLVFMRIYS GTIKPQLAIH NINGNCTERI SRLLLPFADQ 430 440 450 460 470 480 HVEIPSLTAG NIALTVGLKH TATGDTIVSS KSSALAAARR AEREGEKKHR QNNEAERLLL 490 500 510 AGVEIPEPVF FCTIEPPSLS KQPGINGLSV STN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification and characterization of two novel human mitochondrial elongation factor genes, hEFG2 and hEFG1, phylogenetically conserved through evolution." Hammarsund M., Wilson W., Corcoran M., Merup M., Einhorn S., Grander D., Sangfelt O. Hum. Genet. 109:542-550(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY.
[2]	"Cloning of elongation factor G isoform." Zheng M., Xie Y., Mao Y. Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4).
[3]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5). Tissue: Colon.
[4]	Xu Y.Y., Sun L.Z., Wu Q.Y., Liu Y.Q., Liu B., Zhao B., Wang X.Y., Song L., Ye J., Sheng H., Gao Y., Zhang C.L., Zhang J., Wei Y.J., Sun Y.H., Jiang Y.X., Zhao X.W., Liu S. , Liu L.S., Ding J.F., Gao R.L., Qiang B.Q., Yuan J.G., Liew C.C., Zhao M.S., Hui R.T. Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2). Tissue: Aorta.
[5]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[6]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3), VARIANTS HIS-425; GLY-594 AND GLY-735. Tissue: Brain and Skin.
[7]	"EF-G2mt is an exclusive recycling factor in mammalian mitochondrial protein synthesis." Tsuboi M., Morita H., Nozaki Y., Akama K., Ueda T., Ito K., Nierhaus K.H., Takeuchi N. Mol. Cell 35:502-510(2009) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION.
[8]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF367997 mRNA. Translation: AAK53401.1. AY453587 mRNA. Translation: AAS49035.1. AK025314 mRNA. Translation: BAB15109.1. AF111808 mRNA. Translation: AAL39010.1. CH471084 Genomic DNA. Translation: EAW95744.1. BC015712 mRNA. Translation: AAH15712.1. BC030612 mRNA. Translation: AAH30612.1.
IPI	IPI00071703. IPI00172648. IPI00216419. IPI00945410. IPI00946969.
RefSeq	NP_115756.2. NM_032380.3. NP_733781.1. NM_170681.1. NP_733792.1. NM_170691.1.
UniGene	Hs.277154.
3D structure databases
ProteinModelPortal	Q969S9.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q969S9. 2 interactions.
STRING	9606.ENSP00000296805.
PTM databases
PhosphoSite	Q969S9.
Polymorphism databases
DMDM	28201798.
Proteomic databases
PaxDb	Q969S9.
PRIDE	Q969S9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000296805; ENSP00000296805; ENSG00000164347. ENST00000345239; ENSP00000296804; ENSG00000164347. ENST00000427854; ENSP00000405808; ENSG00000164347. ENST00000509430; ENSP00000427004; ENSG00000164347.
GeneID	84340.
KEGG	hsa:84340.
UCSC	uc003kdh.1. human. uc003kdi.1. human. uc003kdj.1. human.
Organism-specific databases
CTD	84340.
GeneCards	GC05M074052.
HGNC	HGNC:29682. GFM2.
HPA	HPA036863.
MIM	606544. gene.
neXtProt	NX_Q969S9.
PharmGKB	PA134949527.
GenAtlas	Search...
Phylogenomic databases
eggNOG	COG0480.
HOGENOM	HOG000231585.
InParanoid	Q969S9.
KO	K02355.
OMA	RKATINM.
OrthoDB	EOG4NKBV3.
PhylomeDB	Q969S9.
Gene expression databases
ArrayExpress	Q969S9.
Bgee	Q969S9.
CleanEx	HS_GFM2.
Genevestigator	Q969S9.
GermOnline	ENSG00000164347. Homo sapiens.
Family and domain databases
Gene3D	3.30.230.10. 1 hit. 3.30.70.240. 1 hit.
InterPro	IPR000795. EF_GTP-bd_dom. IPR009022. EFG_III-V. IPR000640. EFG_V. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR005225. Small_GTP-bd_dom. IPR005517. Transl_elong_EFG/EF2_IV. IPR004161. Transl_elong_EFTu/EF1A_2. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
Pfam	PF00679. EFG_C. 1 hit. PF03764. EFG_IV. 1 hit. PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
SMART	SM00838. EFG_C. 1 hit. SM00889. EFG_IV. 1 hit. [Graphical view]
SUPFAM	SSF54980. EFG_III_V. 2 hits. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit. SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR00231. small_GTP. 1 hit.
PROSITE	PS00301. EFACTOR_GTP. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	GFM2. human.
GenomeRNAi	84340.
NextBio	74121.
SOURCE	Search...

Entry information

Entry name

RRF2M_HUMAN

Accession

Primary (citable) accession number: Q969S9
Secondary accession number(s): A0AR28 , Q8N6D8, Q8WYI0, Q9H6Z1

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 2003
Last sequence update:	December 1, 2001
Last modified:	May 1, 2013
This is version 105 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.