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Q969Q0 (RL36L_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 98. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (6) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
60S ribosomal protein L36a-like
Gene names
Name:RPL36AL
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length106 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Cytoplasm Probable.

Tissue specificity

Ubiquitously expressed. Ref.2

Miscellaneous

This gene has no introns in its coding regions, and therefore, was most likely produced by retrotransposition of the original X-linked gene during evolution.

Sequence similarities

Belongs to the ribosomal protein L44e family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Coding sequence diversityPolymorphism
   Molecular functionRibonucleoprotein
Ribosomal protein
   PTMMethylation
   Technical termComplete proteome
Direct protein sequencing
Reference proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentribosome

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionstructural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 10610660S ribosomal protein L36a-like
PRO_0000149118

Amino acid modifications

Modified residue531N6-methyllysine Ref.6

Natural variations

Natural variant661I → V.
Corresponds to variant rs3088024 [ dbSNP | Ensembl ].
VAR_051809

Sequences

Sequence LengthMass (Da)Tools
Q969Q0 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 9C0E08264A578D31

FASTA10612,469
        10         20         30         40         50         60 
MVNVPKTRRT FCKKCGKHQP HKVTQYKKGK DSLYAQGRRR YDRKQSGYGG QTKPIFRKKA 

        70         80         90        100 
KTTKKIVLRL ECVEPNCRSK RMLAIKRCKH FELGGDKKRK GQVIQF 

« Hide

References

« Hide 'large scale' references
[1]"Characterisation of an mRNA encoding a human ribosomal protein homologous to the yeast L44 ribosomal protein."
Davies M.S., Henney A., Ward W.H.J., Craig R.K.
Gene 45:183-191(1986) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Functional second genes generated by retrotransposition of the X-linked ribosomal protein genes."
Uechi T., Maeda N., Tanaka T., Kenmochi N.
Nucleic Acids Res. 30:5369-5375(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY.
[3]"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Halleck A., Ebert L., Mkoundinya M., Schick M., Eisenstein S., Neubert P., Kstrang K., Schatten R., Shen B., Henze S., Mar W., Korn B., Zuo D., Hu Y., LaBaer J.
Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[4]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Kidney and Skeletal muscle.
[5]Bienvenut W.V., Vousden K.H., Lukashchuk N.
Submitted (MAR-2008) to UniProtKB
Cited for: PROTEIN SEQUENCE OF 29-38 AND 100-106, IDENTIFICATION BY MASS SPECTROMETRY.
Tissue: Lung carcinoma.
[6]Bienvenut W.V., Waridel P., Quadroni M.
Submitted (MAR-2009) to UniProtKB
Cited for: PROTEIN SEQUENCE OF 45-57; 70-78 AND 100-106, METHYLATION AT LYS-53, IDENTIFICATION BY MASS SPECTROMETRY.
Tissue: Cervix carcinoma.
[7]"Initial characterization of the human central proteome."
Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M15661 mRNA. Translation: AAA36589.1.
AB063609 mRNA. Translation: BAC19836.1.
CR542166 mRNA. Translation: CAG46963.1.
BC000741 mRNA. Translation: AAH00741.1.
BC003145 mRNA. Translation: AAH03145.1.
BC070207 mRNA. Translation: AAH70207.1.
BC107716 mRNA. Translation: AAI07717.1.
PIRR6HU36. A25560.
RefSeqNP_000992.1. NM_001001.4.
UniGeneHs.444749.
Hs.745129.

3D structure databases

ProteinModelPortalQ969Q0.
SMRQ969Q0. Positions 2-106.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid112085. 13 interactions.
IntActQ969Q0. 8 interactions.
MINTMINT-4829931.
STRING9606.ENSP00000346012.

PTM databases

PhosphoSiteQ969Q0.

Polymorphism databases

DMDM57013007.

Proteomic databases

PaxDbQ969Q0.
PRIDEQ969Q0.

Protocols and materials databases

DNASU6166.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000298289; ENSP00000346012; ENSG00000165502.
GeneID6166.
KEGGhsa:6166.
UCSCuc001wwq.2. human.

Organism-specific databases

CTD6166.
GeneCardsGC14M050086.
HGNCHGNC:10346. RPL36AL.
MIM180469. gene.
neXtProtNX_Q969Q0.
PharmGKBPA34732.
GenAtlasSearch...

Phylogenomic databases

eggNOGCOG1631.
HOGENOMHOG000224989.
HOVERGENHBG056127.
InParanoidQ969Q0.
KOK02929.
OMAHTIHKVE.
OrthoDBEOG7D59R2.
PhylomeDBQ969Q0.
TreeFamTF300213.

Gene expression databases

BgeeQ969Q0.
CleanExHS_RPL36AL.
GenevestigatorQ969Q0.

Family and domain databases

Gene3D3.10.450.80. 1 hit.
InterProIPR000552. Ribosomal_L44e.
IPR011332. Ribosomal_zn-bd.
[Graphical view]
PANTHERPTHR10369. PTHR10369. 1 hit.
PfamPF00935. Ribosomal_L44. 1 hit.
[Graphical view]
ProDomPD002841. Ribosomal_L44e. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF57829. SSF57829. 1 hit.
PROSITEPS01172. RIBOSOMAL_L44E. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi6166.
NextBio23953.
PROQ969Q0.
SOURCESearch...

Entry information

Entry nameRL36L_HUMAN
AccessionPrimary (citable) accession number: Q969Q0
Secondary accession number(s): Q3B7A5
Entry history
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: January 23, 2007
Last modified: April 16, 2014
This is version 98 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 14

Human chromosome 14: entries, gene names and cross-references to MIM